Alibendol

ChemicalBook > CAS DataBase List > Alibendol

Product Name: Alibendol
CAS No.: 26750-81-2
Chemical Name: Alibendol
Synonyms: fc54;PC-54;H-3774;Cebera;EB 1856;Ailbendol;ALIBENDOL;Alibendol powder;Alibendol USP/EP/BP;5-allyl-2-hydroxy-n-(2-hydroxyethyl)-m-anisamid
CBNumber: CB0108681
Molecular Formula: C13H17NO4
Formula Weight: 251.28
MOL File: 26750-81-2.mol

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Alibendol Property

Melting point:: 97-99°C
Boiling point:: 402.4±45.0 °C(Predicted)
Density: 1.192±0.06 g/cm3(Predicted)
storage temp.: Sealed in dry,Room Temperature
solubility: DMSO, Methanol
form: Solid
pka: 8.59±0.48(Predicted)
color: White
λmax: 316nm(EtOH)(lit.)
Merck: 14,244
CAS DataBase Reference: 26750-81-2(CAS DataBase Reference)

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Safety

RTECS: CU8730000
HS Code: 2924.29.7790
Toxicity: LD50 in Swiss male mice (mg/kg): >3000 orally; >2000 s.c.; 209 i.p.; 217 i.v. (Clémence)

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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

TCI Chemical

Product number: A2965
Product name: Alibendol
Purity: >98.0%(GC)
Packaging: 1g
Price: $16
Updated: 2024/03/01

TCI Chemical

Product number: A2965
Product name: Alibendol
Purity: >98.0%(GC)
Packaging: 5g
Price: $41
Updated: 2024/03/01

TRC

Product number: A535930
Product name: Alibendol
Packaging: 50mg
Price: $60
Updated: 2021/12/16

Biosynth Carbosynth

Product number: FA17279
Product name: Alibendol
Packaging: 100mg
Price: $100.5
Updated: 2021/12/16

Chem-Impex

Product number: 37614
Product name: Alibendol,98%(GC)
Purity: 98%(GC)
Packaging: 5G
Price: $143.36
Updated: 2021/12/16

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Alibendol Chemical Properties,Usage,Production

Chemical Properties

White Solid

Originator

Cebera ,Bouchara ,France ,1981

Uses

An amide analog of Eugenol, and is used therapeutically as an antispasmodic.

Uses

Alibendol is an antispasmodic,choleretic, and cholekinetic.

Definition

ChEBI: Alibendol is a member of salicylamides.

Manufacturing Process

36 g of ethyl ester of 2-hydroxy-3-methoxy-5-allyl-benzoic acid [obtained by the process described by Pearl, et al., J. Amer. Chem. Soc., Vol. 71, 1067- 1068 (1949)] and 61 g of ethanolamine were admixed and left to stand for 1 hour at ambient temperature after which it was heated for 1 hour at 120°C. The mixture was extracted with chloroform and the organic phases were washed with half diluted hydrochloric acid, then with water, and the chloroform evaporated off. The residue, after recrystallization from benzene, was a 78% yield of 2-hydroxy-3-methoxy-5-allyl-N-(β-hydroxyethyl)- benzamide having a melting point of 95°C. The product appeared in the form of colorless crystals which were insoluble in water and soluble in dilute sodium hydroxide.

Therapeutic Function

Choleretic, Spasmolytic

Alibendol Preparation Products And Raw materials

Raw materials

Monoethanolamine 4-propylbenzoic acid Ethyl benzoate

Preparation Products

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View Lastest Price from Alibendol manufacturers

Shaanxi Dideu Medichem Co. Ltd

Product: Alibendol 26750-81-2
Price: US $1.00-1.00/Kg/Bag
Min. Order: 1g
Purity: 99%
Supply Ability: 50tons
Release date: 2020-04-30

Hebei Shengyuan Jinlong Import and Export Co. LTD

Product: Alibendol 26750-81-2
Price: US $10.00-5.00/kg
Min. Order: 1kg
Purity: 99
Supply Ability: 500ton/month
Release date: 2022-10-27

Shanxi Naipu Import and Export Co.,Ltd

Product: Alibendol 26750-81-2
Price: US $10.00/KG
Min. Order: 1KG
Purity: 99%
Supply Ability: 500ton/month
Release date: 2020-12-29

26750-81-2, AlibendolRelated Search:

CHLOROPHOSPHONAZO III 3-Diethylaminophenol 2-(METHYLSULFONYL)ETHANOL Methoxydiethylborane p-(2-Methoxyethyl) phenol Benzamide Chlorantraniliprole 2-Methoxyethanol FTIBAMZONE Sulfamic acid 5-Methylsalicylamide 5-ALLYL-2-HYDROXY-3-METHOXYBENZALDEHYDE RADICININ FROM ALTERNARIA CHRYSANTHEMI N-(2-HYDROXYETHYL)SALICYLAMIDE, 98 Alibendol Aliskiren Methoxy

hydroxy-2methoxy-3allyl-5n-(beta-hydroxyethyl)benzamide

Alibendol ,2-hydroxy-3-methoxy-5-allyl-N-(C-hydroxyethyl)-benzamide

5-Allyl-2-hydroxy-N-(2-hydroxyethyl)-3-methoxybenzamide

5-Allyl-N-(2-hydroxyethyl)-3-methoxysalicylamide

Cebera

H-3774

PC-54

2-hydroxy-N-(2-hydroxyethyl)-3-methoxy-5-prop-2-enylbenzamide

2-hydroxy-N-(2-hydroxyethyl)-3-methoxy-5-prop-2-enyl-benzamide

2-Hydroxy-N-(2-hydroxyethyl)-3-Methoxy-5-(2-propen-1-yl)benzaMide

5-Allyl-2-hydroxy-N-(2-hydroxyethyl)-M-anisaMide

EB 1856

5-allyl-2-hydroxy-n-(2-hydroxyethyl)-3-methoxy-benzamid

5-allyl-2-hydroxy-n-(2-hydroxyethyl)-m-anisamid

Ailbendol

fc54

ALIBENDOL

2-hydroxy-n-(2-hydroxyethyl)-3-methoxy-5-(2-propenyl)benzamide

2-hydroxy-n-(2-hydroxyethyl)-3-methoxy-5-(2-propenyl)-benzamid

5,6-bis(2-hydroxyethylthio)-1H-benzimidazole-4,7-dione

Benzamide,2-hydroxy-N-(2-hydroxyethyl)-3-methoxy-5-(2-propen-1-yl)

Alibendol USP/EP/BP

Alibendol powder

2-hydroxy-N-(2-hydroxyethyl)-3-methoxy-5-(prop-2-en-1-yl)benzamide

26750-81-2

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