6-[2-(3,4-diethoxyphenyl)-1,3-thiazol-4-yl]pyridine-2-carboxylic acid

Product Name: 6-[2-(3,4-diethoxyphenyl)-1,3-thiazol-4-yl]pyridine-2-carboxylic acid
CAS No.: 145739-56-6
Chemical Name: 6-[2-(3,4-diethoxyphenyl)-1,3-thiazol-4-yl]pyridine-2-carboxylic acid
Synonyms: OPC-6535;TETOMILAST;-(4-hydroxyphenyl)acrylaldehyde;Tetomilast (Synonyms: OPC-6535);6-(2-(3,4-diethoxyphenyl)thiazol-4-yl)picolinic acid;6-[2-(3,4-diethoxyphenyl)-thiazole-4-yl]pyridine-2-carboxylic acid;2-Pyridinecarboxylic acid, 6-[2-(3,4-diethoxyphenyl)-4-thiazolyl]-;6-[2-(3,4-Diethoxy-phenyl)-thiazol-4-yl]-pyridine-2-carboxylic acid;6-[2-(3,4-diethoxyphenyl)-1,3-thiazol-4-yl]pyridine-2-carboxylic acid
CBNumber: CB01258549
Molecular Formula: C19H18N2O4S
Formula Weight: 370.42
MOL File: 145739-56-6.mol

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6-[2-(3,4-diethoxyphenyl)-1,3-thiazol-4-yl]pyridine-2-carboxylic acid Property

Boiling point:: 598.6±60.0 °C(Predicted)
Density: 1.279±0.06 g/cm3(Predicted)
storage temp.: Sealed in dry,Room Temperature
pka: 3.28±0.10(Predicted)
form: Solid
color: White to off-white

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

American Custom Chemicals Corporation

Product number: CHM1014659
Product name: 6-[2-(3,4-DIETHOXYPHENYL)-1,3-THIAZOL-4-YL]PYRIDINE-2-CARBOXYLIC ACID
Purity: 95.00%
Packaging: 5MG
Price: $505.42
Updated: 2021/12/16

Chemenu

Product number: CM177913
Product name: 6-(2-(3,4-diethoxyphenyl)thiazol-4-yl)picolinicacid
Purity: 95%
Packaging: 1g
Price: $1222
Updated: 2021/12/16

Crysdot

Product number: CD11253526
Product name: 6-(2-(3,4-Diethoxyphenyl)thiazol-4-yl)picolinicacid
Purity: 95+%
Packaging: 1g
Price: $1297
Updated: 2021/12/16

Crysdot

Product number: CD11253526
Product name: 6-(2-(3,4-Diethoxyphenyl)thiazol-4-yl)picolinicacid
Purity: 95+%
Packaging: 5g
Price: $3120
Updated: 2021/12/16

Crysdot

Product number: CD11253526
Product name: 6-(2-(3,4-Diethoxyphenyl)thiazol-4-yl)picolinicacid
Purity: 95+%
Packaging: 10g
Price: $4683
Updated: 2021/12/16

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6-[2-(3,4-diethoxyphenyl)-1,3-thiazol-4-yl]pyridine-2-carboxylic acid Chemical Properties,Usage,Production

Uses

Tetomilast (OPC-6535) is a PDE4 inhibitor with potential for the research of inflammatory bowel disease (IBD) and chronic obstructive pulmonary disease (COPD).

IC 50

PDE4

References

[1] Ichikawa H, Okamoto S, Kamada N, et al. Tetomilast suppressed production of proinflammatory cytokines from human monocytes and ameliorated chronic colitis in IL-10-deficient mice. Inflamm Bowel Dis. 2008;14(11):1483-1490. DOI:10.1002/ibd.20524

6-[2-(3,4-diethoxyphenyl)-1,3-thiazol-4-yl]pyridine-2-carboxylic acid Preparation Products And Raw materials

Raw materials

Preparation Products

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6-[2-(3,4-diethoxyphenyl)-1,3-thiazol-4-yl]pyridine-2-carboxylic acid Suppliers

China 26 United States 1 Global 27

Shanghai Boyle Chemical Co., Ltd.

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Chembest Research Laboratories Limited

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Heterochem

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Hangzhou Sage Chemical Co., Ltd.

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Lanzhou Angeli Biochemical Technology Co., Ltd.

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Shanghai YuanYe Biotechnology Co., Ltd.

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Shanghai Rechem science Co., Ltd.

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Shanghai Biopharmaleader Co., Ltd.

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View Lastest Price from 6-[2-(3,4-diethoxyphenyl)-1,3-thiazol-4-yl]pyridine-2-carboxylic acid manufacturers

Career Henan Chemical Co

Product: TETOMILAST 145739-56-6
Price: US $2.00/KG
Min. Order: 1KG
Purity: 98%min
Supply Ability: ask
Release date: 2019-12-19

145739-56-6, 6-[2-(3,4-diethoxyphenyl)-1,3-thiazol-4-yl]pyridine-2-carboxylic acidRelated Search:

-(4-hydroxyphenyl)acrylaldehyde

6-[2-(3,4-diethoxyphenyl)-1,3-thiazol-4-yl]pyridine-2-carboxylic acid

6-(2-(3,4-diethoxyphenyl)thiazol-4-yl)picolinic acid

6-[2-(3,4-Diethoxy-phenyl)-thiazol-4-yl]-pyridine-2-carboxylic acid

TETOMILAST

2-Pyridinecarboxylic acid, 6-[2-(3,4-diethoxyphenyl)-4-thiazolyl]-

6-[2-(3,4-diethoxyphenyl)-thiazole-4-yl]pyridine-2-carboxylic acid

Tetomilast (Synonyms: OPC-6535)

OPC-6535

145739-56-6