ChemicalBook > CAS DataBase List > 6-[2-(3,4-diethoxyphenyl)-1,3-thiazol-4-yl]pyridine-2-carboxylic acid
6-[2-(3,4-diethoxyphenyl)-1,3-thiazol-4-yl]pyridine-2-carboxylic acid
- Product Name
- 6-[2-(3,4-diethoxyphenyl)-1,3-thiazol-4-yl]pyridine-2-carboxylic acid
- CAS No.
- 145739-56-6
- Chemical Name
- 6-[2-(3,4-diethoxyphenyl)-1,3-thiazol-4-yl]pyridine-2-carboxylic acid
- Synonyms
- OPC-6535;TETOMILAST;-(4-hydroxyphenyl)acrylaldehyde;Tetomilast (Synonyms: OPC-6535);6-(2-(3,4-diethoxyphenyl)thiazol-4-yl)picolinic acid;6-[2-(3,4-diethoxyphenyl)-thiazole-4-yl]pyridine-2-carboxylic acid;2-Pyridinecarboxylic acid, 6-[2-(3,4-diethoxyphenyl)-4-thiazolyl]-;6-[2-(3,4-Diethoxy-phenyl)-thiazol-4-yl]-pyridine-2-carboxylic acid;6-[2-(3,4-diethoxyphenyl)-1,3-thiazol-4-yl]pyridine-2-carboxylic acid
- CBNumber
- CB01258549
- Molecular Formula
- C19H18N2O4S
- Formula Weight
- 370.42
- MOL File
- 145739-56-6.mol
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6-[2-(3,4-diethoxyphenyl)-1,3-thiazol-4-yl]pyridine-2-carboxylic acid Property
- Boiling point:
- 598.6±60.0 °C(Predicted)
- Density
- 1.279±0.06 g/cm3(Predicted)
- storage temp.
- Sealed in dry,Room Temperature
- pka
- 3.28±0.10(Predicted)
- form
- Solid
- color
- White to off-white
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Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H302Harmful if swallowed
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
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N-Bromosuccinimide Price
American Custom Chemicals Corporation
- Product number
- CHM1014659
- Product name
- 6-[2-(3,4-DIETHOXYPHENYL)-1,3-THIAZOL-4-YL]PYRIDINE-2-CARBOXYLIC ACID
- Purity
- 95.00%
- Packaging
- 5MG
- Price
- $505.42
- Updated
- 2021/12/16
Chemenu
- Product number
- CM177913
- Product name
- 6-(2-(3,4-diethoxyphenyl)thiazol-4-yl)picolinicacid
- Purity
- 95%
- Packaging
- 1g
- Price
- $1222
- Updated
- 2021/12/16
Crysdot
- Product number
- CD11253526
- Product name
- 6-(2-(3,4-Diethoxyphenyl)thiazol-4-yl)picolinicacid
- Purity
- 95+%
- Packaging
- 1g
- Price
- $1297
- Updated
- 2021/12/16
Crysdot
- Product number
- CD11253526
- Product name
- 6-(2-(3,4-Diethoxyphenyl)thiazol-4-yl)picolinicacid
- Purity
- 95+%
- Packaging
- 5g
- Price
- $3120
- Updated
- 2021/12/16
Crysdot
- Product number
- CD11253526
- Product name
- 6-(2-(3,4-Diethoxyphenyl)thiazol-4-yl)picolinicacid
- Purity
- 95+%
- Packaging
- 10g
- Price
- $4683
- Updated
- 2021/12/16
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6-[2-(3,4-diethoxyphenyl)-1,3-thiazol-4-yl]pyridine-2-carboxylic acid Chemical Properties,Usage,Production
Uses
Tetomilast (OPC-6535) is a PDE4 inhibitor with potential for the research of inflammatory bowel disease (IBD) and chronic obstructive pulmonary disease (COPD).
IC 50
PDE4
References
[1] Ichikawa H, Okamoto S, Kamada N, et al. Tetomilast suppressed production of proinflammatory cytokines from human monocytes and ameliorated chronic colitis in IL-10-deficient mice. Inflamm Bowel Dis. 2008;14(11):1483-1490. DOI:10.1002/ibd.20524
6-[2-(3,4-diethoxyphenyl)-1,3-thiazol-4-yl]pyridine-2-carboxylic acid Preparation Products And Raw materials
Raw materials
Preparation Products
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6-[2-(3,4-diethoxyphenyl)-1,3-thiazol-4-yl]pyridine-2-carboxylic acid Suppliers
- Tel
- --
- Fax
- --
- sales@honestjoy.cn
- Country
- United States
- ProdList
- 6675
- Advantage
- 54
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View Lastest Price from 6-[2-(3,4-diethoxyphenyl)-1,3-thiazol-4-yl]pyridine-2-carboxylic acid manufacturers
Career Henan Chemical Co
- Product
- TETOMILAST 145739-56-6
- Price
- US $2.00/KG
- Min. Order
- 1KG
- Purity
- 98%min
- Supply Ability
- ask
- Release date
- 2019-12-19