ChemicalBook > CAS DataBase List > (S)-(-)-2-Azetidinecarboxylic acid

(S)-(-)-2-Azetidinecarboxylic acid

Product Name
(S)-(-)-2-Azetidinecarboxylic acid
CAS No.
2133-34-8
Chemical Name
(S)-(-)-2-Azetidinecarboxylic acid
Synonyms
(S)-AZETIDINE-2-CARBOXYLIC ACID;H-AZE-OH;L-AZETIDINE-2-CARBOXYLIC ACID;L-H-Aze-OH;H-AZE(2)-OH;(S)-(-)-2-Azetidinec;N,3-Methylene-L-alanine;L-AZETIDINECARBOXYLIC ACID;l-2-azetidinecarboxylicaci;azetidyl-2-carboxylic acid
CBNumber
CB0128117
Molecular Formula
C4H7NO2
Formula Weight
101.1
MOL File
2133-34-8.mol
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(S)-(-)-2-Azetidinecarboxylic acid Property

Melting point:
~215 °C (dec.)
alpha 
-125 º (c=1, water 25 ºC)
Boiling point:
189.47°C (rough estimate)
Density 
1.2245 (rough estimate)
refractive index 
-122 ° (C=4, H2O)
storage temp. 
Keep in dark place,Inert atmosphere,Room temperature
solubility 
Aqueous Base (Slightly), Methanol (Slightly), Water (Slightly)
pka
2.35±0.20(Predicted)
form 
Crystalline Powder or Crystals
color 
White to light beige
Water Solubility 
5 g/100 mL
Merck 
14,908
BRN 
80678
InChIKey
IADUEWIQBXOCDZ-VKHMYHEASA-N
CAS DataBase Reference
2133-34-8(CAS DataBase Reference)
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Safety

Hazard Codes 
Xi
Risk Statements 
36/37/38
Safety Statements 
24/25-36-26
WGK Germany 
3
RTECS 
CM4310500
Hazard Note 
Irritant
HS Code 
29339900
Hazardous Substances Data
2133-34-8(Hazardous Substances Data)
Toxicity
LD50 scu-mus: 1000 mg/kg 85GDA2 8(1),101,82
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
A0760
Product name
L-Azetidine-2-carboxylic acid
Purity
≥99%
Packaging
50mg
Price
$85.9
Updated
2024/03/01
Sigma-Aldrich
Product number
A0760
Product name
L-Azetidine-2-carboxylic acid
Purity
≥99%
Packaging
1g
Price
$711
Updated
2024/03/01
TCI Chemical
Product number
A1043
Product name
L-Azetidine-2-carboxylic Acid [Antagonist of L-Proline]
Purity
>98.0%(T)
Packaging
1g
Price
$279
Updated
2024/03/01
TCI Chemical
Product number
A1043
Product name
L-Azetidine-2-carboxylic Acid [Antagonist of L-Proline]
Purity
>98.0%(T)
Packaging
100mg
Price
$49
Updated
2024/03/01
Alfa Aesar
Product number
L09668
Product name
(S)-(-)-Azetidine-2-carboxylic acid, 98%
Packaging
250mg
Price
$120.65
Updated
2024/03/01
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(S)-(-)-2-Azetidinecarboxylic acid Chemical Properties,Usage,Production

Chemical Properties

white to light yellow crystal powder

Uses

Specific proline antagonist. Used in synthesis of abnormally high molecular weight polypeptides.

Uses

L-Azetidine-2-carboxylic acid has been used as a:

  • collagen synthesis inhibitor
  • protein folding antagonist
  • as a standard in liquid chromatography-mass spectrometry

Uses

(S)-(-)-2-Azetidinecarboxylic acid is a four-membered ring analog of L-Proline, It is a useful intermediate in the synthesis of polypeptides,Used in synthesis of abnormally high molecular weight polypeptides.

Definition

ChEBI: The (S)-enantiomer of azetidine-2-carboxylic acid.

General Description

L-Azetidine-2-carboxylic acid is a non-protein amino acid and teratogenic agent. It is toxic in nature.

Biochem/physiol Actions

Azetidine-2-carboxylic acid (AZC) triggers protein aggregation or upregulates the expression of an aggregation-prone mutant protein, upon interference with nascent protein folding.

Safety Profile

Moderately toxic by subcutaneousroute. An experimental teratogen. Other experimentalreproductive effects. When heated to decomposition itemits toxic fumes of NOx.

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View Lastest Price from (S)-(-)-2-Azetidinecarboxylic acid manufacturers

Honest Joy Holdings Limited
Product
(S)-L-Azetidine-2-carboxylic acid 2133-34-8
Price
US $0.00/KG
Min. Order
1KG
Purity
98.0%
Supply Ability
100 tons
Release date
2022-01-26
Zhuozhou Wenxi import and Export Co., Ltd
Product
(S)-(-)-2-Azetidinecarboxylic acid 2133-34-8
Price
US $15.00-10.00/KG
Min. Order
1KG
Purity
99%+ HPLC
Supply Ability
Monthly supply of 1 ton
Release date
2021-08-10
Zhuozhou Wenxi import and Export Co., Ltd
Product
L-Azetidine-2-carboxylic Acid [Antagonist of L-Proline] 2133-34-8
Price
US $15.00-10.00/KG
Min. Order
1KG
Purity
99%+ HPLC
Supply Ability
Monthly supply of 1 ton
Release date
2021-06-27

2133-34-8, (S)-(-)-2-Azetidinecarboxylic acidRelated Search:


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  • Chiral Building Blocks
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  • Simple 4-Membered Ring Compounds
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  • Cell Biology
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  • BioChemical
  • Cell Signaling and Neuroscience
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  • Peptide Synthesis
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  • Amino Acids 13C, 2H, 15N
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