ChemicalBook > CAS DataBase List > 5-Chloro-2-nitroaniline
5-Chloro-2-nitroaniline
Description Preparation- Product Name
- 5-Chloro-2-nitroaniline
- CAS No.
- 1635-61-6
- Chemical Name
- 5-Chloro-2-nitroaniline
- Synonyms
- 5-CHLORO-2-NITROBENZENAMINE;oro-2-nitroaniL;TIMTEC-BB SBB003828;5-Chlor-2-nitroanilin;5-CHLORO-2-NITROANILINE;2-NITRO-5-CHLOROANILINE;5-Chloro-2-nitroamiline;Atorvastatin Impurity 146;Aniline, 5-chloro-2-nitro-;5-Chloro-2-nitrophenylamine
- CBNumber
- CB0141336
- Molecular Formula
- C6H5ClN2O2
- Formula Weight
- 172.57
- MOL File
- 1635-61-6.mol
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5-Chloro-2-nitroaniline Property
- Melting point:
- 125-129 °C (dec.)(lit.)
- Boiling point:
- 200°C (rough estimate)
- Density
- 1.5610 (rough estimate)
- refractive index
- 1.5870 (estimate)
- storage temp.
- Keep in dark place,Inert atmosphere,Room temperature
- solubility
- soluble in Chloroform, Methanol
- form
- Liquid
- pka
- -1.46±0.25(Predicted)
- color
- Clear colorless to light yellow
- BRN
- 2210201
- InChIKey
- ZCWXYZBQDNFULS-UHFFFAOYSA-N
- CAS DataBase Reference
- 1635-61-6(CAS DataBase Reference)
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Safety
- Hazard Codes
- T+,N,T
- Risk Statements
- 26/27/28-33-51/53
- Safety Statements
- 28-36/37-45-61-28A
- RIDADR
- UN 2237 6.1/PG 3
- WGK Germany
- 3
- F
- 9-23
- Hazard Note
- Irritant
- HazardClass
- 6.1
- PackingGroup
- III
- HS Code
- 29214210
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Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Danger
- Hazard statements
-
H373May cause damage to organs through prolonged or repeated exposure
H411Toxic to aquatic life with long lasting effects
- Precautionary statements
-
P262Do not get in eyes, on skin, or on clothing.
P273Avoid release to the environment.
P280Wear protective gloves/protective clothing/eye protection/face protection.
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N-Bromosuccinimide Price
Sigma-Aldrich
- Product number
- 269050
- Product name
- 5-Chloro-2-nitroaniline
- Purity
- 97%
- Packaging
- 25g
- Price
- $93.7
- Updated
- 2024/03/01
Sigma-Aldrich
- Product number
- 269050
- Product name
- 5-Chloro-2-nitroaniline
- Purity
- 97%
- Packaging
- 5g
- Price
- $55.6
- Updated
- 2023/06/20
TCI Chemical
- Product number
- C1139
- Product name
- 5-Chloro-2-nitroaniline
- Purity
- >99.0%(GC)
- Packaging
- 25g
- Price
- $49
- Updated
- 2024/03/01
TCI Chemical
- Product number
- C1139
- Product name
- 5-Chloro-2-nitroaniline
- Purity
- >99.0%(GC)
- Packaging
- 250g
- Price
- $236
- Updated
- 2024/03/01
Alfa Aesar
- Product number
- A11241
- Product name
- 5-Chloro-2-nitroaniline, 97%
- Packaging
- 25g
- Price
- $84.65
- Updated
- 2024/03/01
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5-Chloro-2-nitroaniline Chemical Properties,Usage,Production
Description
2-Nitro-5-chloroaniline is an important pharmaceutical and veterinary drug intermediate. It has been applied in the upgraded product of veterinary drug albendazole-fenbendazole, and has a broad market prospect.
Preparation
Add 2.46mol of 2,4-dichloronitrobenzene, 7.72mol of toluene to a 3L autoclave, seal the autoclave, replace the air with nitrogen, then pass in 14.1mol of liquid ammonia, increase the temperature to 160℃, continue the reaction for 8h, and then lower the temperature to 40℃, drain the excess ammonia gas, open the kettle, add the obtained solid-liquid mixture to 800mL of water, continue to cool to 10℃, filter, add the resulting filter cake to the water, continue beating and filtering, the obtained solid is crystallized with methanol to obtain 388g , yield 91.2%, the purity of the liquid phase external standard is 99.5%.
Chemical Properties
yellow to orange powder
Uses
5-Chloro-2-nitroaniline is a useful synthetic intermediate. It can be used as a reagent to synthesize benzamide derivatives as histone deacetylase inhibitors. It is an intermediate used to synthesize 1-Nitro Febantel a Febantel impurity.
Uses
5-Chloro-2-nitroaniline was used in the synthesis of 5-(4-substituted piperazin-1-yl)-2-nitroanilines and 5-(4-substituted piperazin-1-yl)benzimidazole-2-carbamates.
Application
5-Chloro-2-nitroaniline was used in the synthesis of 5-(4-substituted piperazin-1-yl)-2-nitroanilines and 5-(4-substituted piperazin-1-yl)benzimidazole-2-carbamates.
The coupling of divinylbenzene cross-linked polystyrene with 5-chloro-2-nitroaniline followed by oxidative decyanation afforded benzophenone.
General Description
The coupling of divinylbenzene cross-linked polystyrene with 5-chloro-2-nitroaniline followed by oxidative decyanation afforded benzophenone.
5-Chloro-2-nitroaniline Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from 5-Chloro-2-nitroaniline manufacturers
Henan Fengda Chemical Co., Ltd
- Product
- 5-Chloro-2-nitroaniline 1635-61-6
- Price
- US $100.00-1.00/KG
- Min. Order
- 1KG
- Purity
- 99%
- Supply Ability
- g-kg-tons, free sample is available
- Release date
- 2023-12-24
Nanjing Fred Technology Co., Ltd
- Product
- 5-Chloro-2-nitroaniline 1635-61-6
- Price
- US $0.00-0.00/kg
- Min. Order
- 1kg
- Purity
- 98%
- Supply Ability
- 1 ton
- Release date
- 2023-12-28
WUHAN FORTUNA CHEMICAL CO., LTD
- Product
- 5-Chloro-2-nitroaniline 1635-61-6
- Price
- US $0.00/KG
- Min. Order
- 1KG
- Purity
- 98%min
- Supply Ability
- 30tons/month
- Release date
- 2023-02-24
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