Cbz-D-Valine
- Product Name
- Cbz-D-Valine
- CAS No.
- 1685-33-2
- Chemical Name
- Cbz-D-Valine
- Synonyms
- Z-D-Val;CBZ-D-VAL;Z-D-VAL-OH;Z-D-VALINE;CBZ-D-VALINE;CBZ-D-VAL-OH;Z-D-valine99%;N-CBZ-D-VAL-OH;N-CBZ-D-VALINE;Z-D-VALINE extrapure
- CBNumber
- CB0143789
- Molecular Formula
- C13H17NO4
- Formula Weight
- 251.28
- MOL File
- 1685-33-2.mol
Cbz-D-Valine Property
- Melting point:
- 58-60°C
- Boiling point:
- 432.6±38.0 °C(Predicted)
- Density
- 1.182±0.06 g/cm3(Predicted)
- refractive index
- 4 ° (C=2, AcOH)
- storage temp.
- Sealed in dry,2-8°C
- solubility
- Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc.
- form
- powder to crystal
- pka
- 4.00±0.10(Predicted)
- color
- White to Almost white
- BRN
- 2056616
- InChI
- InChI=1S/C13H17NO4/c1-9(2)11(12(15)16)14-13(17)18-8-10-6-4-3-5-7-10/h3-7,9,11H,8H2,1-2H3,(H,14,17)(H,15,16)/t11-/m1/s1
- InChIKey
- CANZBRDGRHNSGZ-LLVKDONJSA-N
- SMILES
- C(O)(=O)[C@@H](C(C)C)NC(OCC1=CC=CC=C1)=O
- CAS DataBase Reference
- 1685-33-2(CAS DataBase Reference)
Safety
- Safety Statements
- 22-24/25
- HS Code
- 29225090
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H302Harmful if swallowed
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.
P302+P352IF ON SKIN: wash with plenty of soap and water.
P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- C2139
- Product name
- N-Carbobenzoxy-D-valine
- Purity
- >98.0%(T)
- Packaging
- 5g
- Price
- $26
- Updated
- 2025/07/31
- Product number
- C2139
- Product name
- N-Carbobenzoxy-D-valine
- Purity
- >98.0%(T)
- Packaging
- 25g
- Price
- $101
- Updated
- 2025/07/31
- Product number
- C227780
- Product name
- N-Cbz-D-valine
- Packaging
- 25g
- Price
- $365
- Updated
- 2021/12/16
- Product number
- 242694
- Product name
- Z-D-valine 99+%
- Packaging
- 1g
- Price
- $156
- Updated
- 2021/12/16
- Product number
- C227780
- Product name
- N-Cbz-D-valine
- Packaging
- 5g
- Price
- $120
- Updated
- 2021/12/16
Cbz-D-Valine Chemical Properties,Usage,Production
Uses
N-Cbz-D-valine is the N-Cbz-protected form of D-Valine (V094200). D-Valine (an isomer of the essential amino acid L-Valine [V094205])exhibited inhibitory effects on fibroblasts that contaminated mammalian kidney cultures, allowing for selective growth epithelial cells. D-Valine is also known for its presence in the structure of Actinomycin D, an antitumour drug. D-Valine is naturally synthesized by Streptomyces antibioticus.
Synthesis
At 0??C, 10 mmol of D-valine was dissolved in 50 ml of a saturated solution of sodium bicarbonate (NaHCO3) at this temperature to obtain the dissolved solution, and the reaction was carried out with 11 mmol of benzyl chloroformate added dropwise to the dissolved solution at a rate of 1 drop/10 s while stirring, dropwise Finished, placed at 30 ??, stirring reaction 15 hours, do thin layer detection, measured that the solution is completely reacted, and then washed with 50 ml / times of ether 3 times, discard the ether, get the aqueous phase, the aqueous phase with a mass concentration of 30% of the concentrated hydrochloric acid adjusted PH to 3, the emergence of milky white solids, on the emergence of milky white solids after the liquid was extracted with 50 ml / time of ethyl acetate for 3 times, merged, and combined the liquid in turn, the combined solution was extracted with 50 ml / time of ethyl acetate, the combined liquid with 50 ml / time of ethyl acetate, the combined liquid with 50 ml The combined solution was sequentially extracted with 50 ml/time of ethyl acetate. The combined solution was washed twice with 50 ml/time of distilled water and once with 50 ml of saturated saline, then dried with anhydrous magnesium sulfate for 7 hours, filtered, and the filtrate was concentrated under reduced pressure to obtain a light yellow oil, which was purified by chromatography column using mixed solvent of ethyl acetate and petroleum ether with the ratio of 1:3 by volume as the mobile phase, and was obtained as N-Cbz-D-valine, which was a colorless, light-white solid. -Valine, as colorless transparent oil, the yield was 68.7%.
Cbz-D-Valine Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from Cbz-D-Valine manufacturers
- Product
- Cbz-D-Valine 1685-33-2
- Price
- US $2.00/kg
- Min. Order
- 1kg
- Purity
- 0.99
- Supply Ability
- 10000
- Release date
- 2024-08-14
- Product
- Cbz-D-Valine 1685-33-2
- Price
- US $9.90/KG
- Min. Order
- 1KG
- Purity
- 99%
- Supply Ability
- 10 mt
- Release date
- 2024-11-29
- Product
- Cbz-D-Val-OH 1685-33-2
- Price
- US $0.00-0.00/kg
- Min. Order
- 1kg
- Purity
- 98%
- Supply Ability
- 1T
- Release date
- 2023-12-18