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DESTRUXIN A

Product Name
DESTRUXIN A
CAS No.
6686-70-0
Chemical Name
DESTRUXIN A
Synonyms
DESTRUXIN A;destruxin A from metarhizium anisopliae;Destruxin A from Metarrhizium anisopliae;Destruxin A, 98%, from Metarhizium anisopliae;Destruxin A from Metarrhizium anisopliae;Destruxin A from Metarrhizium anisopliae >=98% (HPLC);3-Ethenylcyclo(D-Lac-L-Pro-L-Ile-N-methyl-L-Val-N-methyl-L-Ala-βAla-);Cyclo[N-methyl-L-alanyl-β-alanyl-(2R)-2-hydroxy-4-pentenoyl-L-prolyl-L-isoleucyl-N-methyl-L-valyl];N-[N-[(R)-2-Hydroxy-1-oxo-4-pentenyl]-L-Pro-L-Ile-N-methyl-L-Val-N-methyl-L-Ala-]-β-alanine lactone;N-[N-[(2R)-1-Oxo-2-hydroxy-4-pentenyl]-L-Pro-L-Ile-N-methyl-L-Val-N-methyl-L-Ala-]-β-alanine lactone
CBNumber
CB0148047
Molecular Formula
C29H47N5O7
Formula Weight
577.71
MOL File
6686-70-0.mol
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DESTRUXIN A Property

Melting point:
188-189 °C
Boiling point:
875.6±65.0 °C(Predicted)
Density 
1.18±0.1 g/cm3(Predicted)
storage temp. 
-20°C
solubility 
Acetonitrile: Soluble; DMF: Soluble; DMSO: Soluble
form 
A powder
pka
13.53±0.70(Predicted)
color 
White to off-white
biological source
Metarrhizium anisopliae
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Safety

Hazard Codes 
Xn
Risk Statements 
20/21/22-36/37/38-48
Safety Statements 
26-36-45
WGK Germany 
3
RTECS 
HH1500000
HS Code 
2933790090
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
D4921
Product name
Destruxin A from Metarrhizium anisopliae
Purity
≥98% (HPLC)
Packaging
1mg
Price
$960
Updated
2025/07/31
Cayman Chemical
Product number
20428
Product name
Destruxin A
Purity
≥96%
Packaging
1mg
Price
$536
Updated
2024/03/01
Apolloscientific
Product number
BID1011
Product name
DestruxinAfromMetarhiziumanisopliae
Packaging
100ug
Price
$102
Updated
2021/12/16
American Custom Chemicals Corporation
Product number
TOX0000067
Product name
DESTRUXIN A
Purity
95.00%
Packaging
5MG
Price
$500.09
Updated
2021/12/16
Apolloscientific
Product number
BID1011
Product name
DestruxinAfromMetarhiziumanisopliae
Packaging
1mg
Price
$537
Updated
2021/12/16
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DESTRUXIN A Chemical Properties,Usage,Production

Uses

Destruxin A from Metarrhizium anisopliae has been used for immersion and inoculation bioassay in Rhipicephalus (Boophilus) microplus. It has been used as a transport inhibitor in Drosophila melanogaster.

Biochem/physiol Actions

Destruxin A is a cyclic hexadepsipeptide produced by fungus causing paralysis and death in insects. May suppress the insect immune response. Possesses an inhibitory activity on leukemic cell proliferation, decreasing the number of cells in G2/M phase. It is virustatic against arboviruses.

in vivo

Destruxin A (injection; 86 μM; single dose) can specifically inhibit the humoral immune response of Drosophila melanogaster, making the flies more susceptible to bacterial infections[3].

DESTRUXIN A Preparation Products And Raw materials

Raw materials

Preparation Products

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DESTRUXIN A Suppliers

China 39 Switzerland 1 United Kingdom 2 United States 5 Global 47
Carbosynth
Tel
--
Fax
--
Email
sales@carbosynth.com
Country
United Kingdom
ProdList
6005
Advantage
58
Apollo Scientific Ltd.
Tel
--
Fax
--
Email
sales@apolloscientific.co.uk
Country
United Kingdom
ProdList
6084
Advantage
88

6686-70-0, DESTRUXIN ARelated Search:

DESTRUXIN A

  • 3-Ethenylcyclo(D-Lac-L-Pro-L-Ile-N-methyl-L-Val-N-methyl-L-Ala-βAla-)
  • N-[N-[(2R)-1-Oxo-2-hydroxy-4-pentenyl]-L-Pro-L-Ile-N-methyl-L-Val-N-methyl-L-Ala-]-β-alanine lactone
  • N-[N-[(R)-2-Hydroxy-1-oxo-4-pentenyl]-L-Pro-L-Ile-N-methyl-L-Val-N-methyl-L-Ala-]-β-alanine lactone
  • Destruxin A from Metarrhizium anisopliae
  • Destruxin A, 98%, from Metarhizium anisopliae
  • DESTRUXIN A
  • destruxin A from metarhizium anisopliae
  • Cyclo[N-methyl-L-alanyl-β-alanyl-(2R)-2-hydroxy-4-pentenoyl-L-prolyl-L-isoleucyl-N-methyl-L-valyl]
  • Destruxin A from Metarrhizium anisopliae >=98% (HPLC)
  • Destruxin A from <i>Metarrhizium anisopliae</i>
  • 6686-70-0
  • C29H47N5O7
  • Apoptosis and Cell Cycle
  • BioChemical
  • Cell Biology
  • Cell Signaling and Neuroscience
  • Cell Cycle
  • Cell Cycle Regulators
  • Apoptosis and Cell Cycle
  • Cell Cycle
  • Cell Cycle Regulators