6-CHLOROQUINOLINE-2-CARBOXYLIC ACID

Product Name: 6-CHLOROQUINOLINE-2-CARBOXYLIC ACID
CAS No.: 59394-30-8
Chemical Name: 6-CHLOROQUINOLINE-2-CARBOXYLIC ACID
Synonyms: AKOS A0602-0951;6-CHLOROQUINOLINE-2-CARBOXYLIC ACID;6-Chloro-2-quinolinecarboxylic acid;2-Quinolinecarboxylic acid, 6-chloro-
CBNumber: CB02451013
Molecular Formula: C10H6ClNO2
Formula Weight: 207.61
MOL File: 59394-30-8.mol

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6-CHLOROQUINOLINE-2-CARBOXYLIC ACID Property

Melting point:: 228 °C
Boiling point:: 382.1±27.0 °C(Predicted)
Density: 1.469±0.06 g/cm3(Predicted)
storage temp.: 2-8°C
pka: 4.45±0.43(Predicted)
Appearance: White to yellow Solid

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

AstaTech

Product number: 50648
Product name: 6-CHLOROQUINOLINE-2-CARBOXYLIC ACID
Purity: 97%
Packaging: 0.25G
Price: $89
Updated: 2026/04/30

AstaTech

Product number: 50648
Product name: 6-CHLOROQUINOLINE-2-CARBOXYLIC ACID
Purity: 97%
Packaging: 1G
Price: $223
Updated: 2026/04/30

AstaTech

Product number: 50648
Product name: 6-CHLOROQUINOLINE-2-CARBOXYLIC ACID
Purity: 97%
Packaging: 5G
Price: $774
Updated: 2026/04/30

Matrix Scientific

Product number: 223359
Product name: 6-Chloroquinoline-2-carboxylic acid
Packaging: 100.00mg
Price: $90
Updated: 2026/05/18

Matrix Scientific

Product number: 223359
Product name: 6-Chloroquinoline-2-carboxylic acid
Packaging: 250.00mg
Price: $154
Updated: 2026/05/18

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6-CHLOROQUINOLINE-2-CARBOXYLIC ACID Chemical Properties,Usage,Production

Synthesis

59394-26-2

59394-30-8

General procedure for the synthesis of 6-chloro-2-quinoline carboxylic acid from 6-chloro-2-quinoline carboxaldehyde: A solution of sodium chlorite (2.4 g) and sodium dihydrogen phosphate (2.4 g) in water (24 ml) was added slowly and dropwise over a period of 5 min to a solution of 6-chloroquinoline-2-carboxaldehyde (536 mg; 2.8 mmol) dissolved in a tert-butanol (56 ml) and 2-methyl-2-butene (14 ml) mixed solution. The reaction mixture was stirred at room temperature for 4 hours. After completion of the reaction, the organic solvent was removed by distillation under reduced pressure. Water (30 ml) was added to the residue and a white precipitate was precipitated. The precipitate was collected by filtration, washed with water and dried under vacuum in the presence of phosphorus pentoxide to afford 6-chloroquinoline-2-carboxylic acid in white powder form (505 mg; yield = 87%). Mass spectrometry/liquid chromatography analysis: m/z=208.01 (M+H), retention time=8.55 min (condition 1). NMR hydrogen spectrum (DMSO-d6,400MHz) δ: 8.41-8.39 (m, 1H, aromatic H); 8.20-8.11 (m, 3H, aromatic H); 7.82-7.79 (m, 1H, aromatic H).

References

[1] Patent: US2005/154039, 2005, A1. Location in patent: Page/Page column 11
[2] Tetrahedron, 2013, vol. 69, # 38, p. 8209 - 8215

6-CHLOROQUINOLINE-2-CARBOXYLIC ACID Preparation Products And Raw materials

Raw materials

Preparation Products

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6-CHLOROQUINOLINE-2-CARBOXYLIC ACID Suppliers

China 28 India 1 United States 3 Global 32

Nantong Bosu Pharmaceutical Technology Co., Ltd.

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Career Henan Chemica Co

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6-CHLOROQUINOLINE-2-CARBOXYLIC ACID

AKOS A0602-0951

6-Chloro-2-quinolinecarboxylic acid

2-Quinolinecarboxylic acid, 6-chloro-

59394-30-8