ChemicalBook > CAS DataBase List > N-[4-[4-(2,3-DICHLOROPHENYL)-1-PIPERAZINYL]BUTYL]-9H-FLUORENE-2-CARBOXAMIDE HYDROCHLORIDE
N-[4-[4-(2,3-DICHLOROPHENYL)-1-PIPERAZINYL]BUTYL]-9H-FLUORENE-2-CARBOXAMIDE HYDROCHLORIDE
- Product Name
- N-[4-[4-(2,3-DICHLOROPHENYL)-1-PIPERAZINYL]BUTYL]-9H-FLUORENE-2-CARBOXAMIDE HYDROCHLORIDE
- CAS No.
- 189060-98-8
- Chemical Name
- N-[4-[4-(2,3-DICHLOROPHENYL)-1-PIPERAZINYL]BUTYL]-9H-FLUORENE-2-CARBOXAMIDE HYDROCHLORIDE
- Synonyms
- N B2904;Ngb-2904;Ngb 2904;NGB2904 HCl;NGB 2904 HYDROCHLORIDE;NGB 2904, 10 mM in DMSO;N-(4-(4-(2,3-Dichlorophenyl)-1-piperazinyl)butyl)-3-fluorenylcarboxamide;N-[4-[4-(2,3-Dichlorophenyl)-1-piperazinyl]butyl]-9H-fluorene-2-carboxamide;N-[4-[4-(2,3-dichlorophenyl)piperazin-1-yl]butyl]-9H-fluorene-2-carboxamide;9H-Fluorene-2-carboxamide, N-(4-(4-(2,3-dichlorophenyl)-1-piperazinyl)butyl)-
- CBNumber
- CB02453431
- Molecular Formula
- C28H29Cl2N3O
- Formula Weight
- 494.46
- MOL File
- 189060-98-8.mol
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N-[4-[4-(2,3-DICHLOROPHENYL)-1-PIPERAZINYL]BUTYL]-9H-FLUORENE-2-CARBOXAMIDE HYDROCHLORIDE Property
- Boiling point:
- 691.0±55.0 °C(Predicted)
- Density
- 1.264±0.06 g/cm3(Predicted)
- storage temp.
- Desiccate at +4°C
- solubility
- DMSO: 25 mM,Ethanol: 5 mM
- pka
- 14.70±0.20(Predicted)
- form
- Solid
- color
- White to off-white
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N-Bromosuccinimide Price
Tocris
- Product number
- 2635
- Product name
- NGB2904
- Purity
- ≥98%(HPLC)
- Packaging
- 10
- Price
- $217
- Updated
- 2021/12/16
Tocris
- Product number
- 2635
- Product name
- NGB2904
- Purity
- ≥98%(HPLC)
- Packaging
- 50
- Price
- $872
- Updated
- 2021/12/16
TRC
- Product number
- N393505
- Product name
- NGB2904
- Packaging
- 10mg
- Price
- $160
- Updated
- 2021/12/16
Usbiological
- Product number
- 255979
- Product name
- NGB 2904
- Packaging
- 10mg
- Price
- $466
- Updated
- 2021/12/16
American Custom Chemicals Corporation
- Product number
- HCH0360490
- Product name
- N-[4-[4-(2,3-DICHLOROPHENYL)-1-PIPERAZINYL]BUTYL]-9H-FLUORENE-2-CARBOXAMIDE HYDROCHLORIDE
- Purity
- 95.00%
- Packaging
- 5MG
- Price
- $501.96
- Updated
- 2021/12/16
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N-[4-[4-(2,3-DICHLOROPHENYL)-1-PIPERAZINYL]BUTYL]-9H-FLUORENE-2-CARBOXAMIDE HYDROCHLORIDE Chemical Properties,Usage,Production
Uses
NGB 2904 is a highly-selective D3DR antagonist.
Biological Activity
Potent and selective dopamine D 3 receptor antagonist (K i values are 1.4, 217, 223, 642, > 5000, > 10000 and > 10000 nM for D 3 , D 2 , 5-HT 2 , α 1 , D 4 , D 1 and D 5 receptors respectively). Potently antagonizes quinpirole-stimulated mitogenesis (IC 50 = 6.8 nM). Attenuates cocaine's rewarding effects and inhibits relapse to drug-seeking behavior.
in vivo
NGB 2904 (26 μg/kg; a single s.c.) enhances amphetamine (26 mg/kg)-stimulated locomotion in wild-type mice[3].
NGB 2904 (0.026 μg-1 mg/kg; a single s.c. or once daily for 7 d) stimulates spontaneous locomotion in wild-type mice[3].
IC 50
D3 Receptor: 1.4 nM (Ki)
N-[4-[4-(2,3-DICHLOROPHENYL)-1-PIPERAZINYL]BUTYL]-9H-FLUORENE-2-CARBOXAMIDE HYDROCHLORIDE Preparation Products And Raw materials
Raw materials
Preparation Products
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N-[4-[4-(2,3-DICHLOROPHENYL)-1-PIPERAZINYL]BUTYL]-9H-FLUORENE-2-CARBOXAMIDE HYDROCHLORIDE Suppliers
- Tel
- 888-539-0666
- Fax
- 888-539-0666
- info@emmx.com
- Country
- United States
- ProdList
- 8447
- Advantage
- 60
- Tel
- +1-781-999-5354; +17819995354
- marketing@targetmol.com
- Country
- United States
- ProdList
- 32435
- Advantage
- 58
- Tel
- --
- Fax
- --
- chemicals@usbio.net
- Country
- United States
- ProdList
- 6214
- Advantage
- 80
189060-98-8, N-[4-[4-(2,3-DICHLOROPHENYL)-1-PIPERAZINYL]BUTYL]-9H-FLUORENE-2-CARBOXAMIDE HYDROCHLORIDERelated Search:
2-FLUORENECARBOXALDEHYDE
1-(2,3-Dichlorophenyl)piperazine hydrochloride
N-[4-[4-(2,3-DICHLOROPHENYL)-1-PIPERAZINYL]BUTYL]-9H-FLUORENE-2-CARBOXAMIDE HYDROCHLORIDE