4-[3-(4-Chlorophenyl)-2,1-benzisoxazol-5-yl]-2-pyrimidinamine

Product Name: 4-[3-(4-Chlorophenyl)-2,1-benzisoxazol-5-yl]-2-pyrimidinamine
CAS No.: 477845-12-8
Chemical Name: 4-[3-(4-Chlorophenyl)-2,1-benzisoxazol-5-yl]-2-pyrimidinamine
Synonyms: PIM-1 Inhibitor 2;PIM1 Kinase Inhibitor IV;PIM1 Inhibitor 2,PIM 1 Inhibitor 2;4-(3-(4-chlorophenyl)benzo[c]isoxazol-5-yl)pyrimidin-2-amine;4-[3-(4-Chlorophenyl)-2,1-benzisoxazol-5-yl]-2-pyrimidinamine;2-Pyrimidinamine, 4-[3-(4-chlorophenyl)-2,1-benzisoxazol-5-yl]-
CBNumber: CB02518918
Molecular Formula: C17H11ClN4O
Formula Weight: 322.75
MOL File: 477845-12-8.mol

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4-[3-(4-Chlorophenyl)-2,1-benzisoxazol-5-yl]-2-pyrimidinamine Property

Boiling point:: 627.1±65.0 °C(Predicted)
Density: 1.398±0.06 g/cm3(Predicted)
storage temp.: Store at +4°C
solubility: Soluble to 75 mM in DMSO
form: Yellow solid
pka: 2.98±0.10(Predicted)
color: Light yellow to yellow

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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Cayman Chemical

Product number: 17809
Product name: Pim-1 Inhibitor 2
Purity: ≥98%
Packaging: 1mg
Price: $32
Updated: 2024/03/01

Cayman Chemical

Product number: 17809
Product name: Pim-1 Inhibitor 2
Purity: ≥98%
Packaging: 5mg
Price: $109
Updated: 2024/03/01

Cayman Chemical

Product number: 17809
Product name: Pim-1 Inhibitor 2
Purity: ≥98%
Packaging: 10mg
Price: $153
Updated: 2024/03/01

Tocris

Product number: 3589
Product name: PIM-1Inhibitor2
Purity: ≥98%(HPLC)
Packaging: 50
Price: $488
Updated: 2021/12/16

Tocris

Product number: 3589
Product name: PIM-1Inhibitor2
Purity: ≥98%(HPLC)
Packaging: 10
Price: $120
Updated: 2021/12/16

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4-[3-(4-Chlorophenyl)-2,1-benzisoxazol-5-yl]-2-pyrimidinamine Chemical Properties,Usage,Production

Uses

Pim-1 is a serine/threonine kinase that targets proteins involved in cell survival and proliferation and has roles in tumorigenesis. Pim-1 inhibitor 2 is a potent Pim-1 inhibitor (Ki = 91 nM) that targets the ATP-binding kinase hinge region.[Cayman Chemical]

Uses

Pim-1 Inhibitor 2 acts as a serione/threonine kinase targeting proteins involved in cell proliferation and survical. Potential anti-tumor agent.

IC 50

PIM1: 91 nM (Ki)

4-[3-(4-Chlorophenyl)-2,1-benzisoxazol-5-yl]-2-pyrimidinamine Preparation Products And Raw materials

Raw materials

Preparation Products

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4-[3-(4-Chlorophenyl)-2,1-benzisoxazol-5-yl]-2-pyrimidinamine Suppliers

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477845-12-8, 4-[3-(4-Chlorophenyl)-2,1-benzisoxazol-5-yl]-2-pyrimidinamineRelated Search:

PIM1 Kinase Inhibitor IV

4-(3-(4-chlorophenyl)benzo[c]isoxazol-5-yl)pyrimidin-2-amine

4-[3-(4-Chlorophenyl)-2,1-benzisoxazol-5-yl]-2-pyrimidinamine

PIM-1 Inhibitor 2

PIM1 Inhibitor 2,PIM 1 Inhibitor 2

2-Pyrimidinamine, 4-[3-(4-chlorophenyl)-2,1-benzisoxazol-5-yl]-

477845-12-8

C17H11CIN4O