ChemicalBook > CAS DataBase List > 4-[3-(4-Chlorophenyl)-2,1-benzisoxazol-5-yl]-2-pyrimidinamine
4-[3-(4-Chlorophenyl)-2,1-benzisoxazol-5-yl]-2-pyrimidinamine
- Product Name
- 4-[3-(4-Chlorophenyl)-2,1-benzisoxazol-5-yl]-2-pyrimidinamine
- CAS No.
- 477845-12-8
- Chemical Name
- 4-[3-(4-Chlorophenyl)-2,1-benzisoxazol-5-yl]-2-pyrimidinamine
- Synonyms
- PIM-1 Inhibitor 2;PIM1 Kinase Inhibitor IV;PIM1 Inhibitor 2,PIM 1 Inhibitor 2;4-(3-(4-chlorophenyl)benzo[c]isoxazol-5-yl)pyrimidin-2-amine;4-[3-(4-Chlorophenyl)-2,1-benzisoxazol-5-yl]-2-pyrimidinamine;2-Pyrimidinamine, 4-[3-(4-chlorophenyl)-2,1-benzisoxazol-5-yl]-
- CBNumber
- CB02518918
- Molecular Formula
- C17H11ClN4O
- Formula Weight
- 322.75
- MOL File
- 477845-12-8.mol
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4-[3-(4-Chlorophenyl)-2,1-benzisoxazol-5-yl]-2-pyrimidinamine Property
- Boiling point:
- 627.1±65.0 °C(Predicted)
- Density
- 1.398±0.06 g/cm3(Predicted)
- storage temp.
- Store at +4°C
- solubility
- Soluble to 75 mM in DMSO
- form
- Yellow solid
- pka
- 2.98±0.10(Predicted)
- color
- Light yellow to yellow
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N-Bromosuccinimide Price
Cayman Chemical
- Product number
- 17809
- Product name
- Pim-1 Inhibitor 2
- Purity
- ≥98%
- Packaging
- 1mg
- Price
- $32
- Updated
- 2024/03/01
Cayman Chemical
- Product number
- 17809
- Product name
- Pim-1 Inhibitor 2
- Purity
- ≥98%
- Packaging
- 5mg
- Price
- $109
- Updated
- 2024/03/01
Cayman Chemical
- Product number
- 17809
- Product name
- Pim-1 Inhibitor 2
- Purity
- ≥98%
- Packaging
- 10mg
- Price
- $153
- Updated
- 2024/03/01
Tocris
- Product number
- 3589
- Product name
- PIM-1Inhibitor2
- Purity
- ≥98%(HPLC)
- Packaging
- 50
- Price
- $488
- Updated
- 2021/12/16
Tocris
- Product number
- 3589
- Product name
- PIM-1Inhibitor2
- Purity
- ≥98%(HPLC)
- Packaging
- 10
- Price
- $120
- Updated
- 2021/12/16
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4-[3-(4-Chlorophenyl)-2,1-benzisoxazol-5-yl]-2-pyrimidinamine Chemical Properties,Usage,Production
Uses
Pim-1 is a serine/threonine kinase that targets proteins involved in cell survival and proliferation and has roles in tumorigenesis. Pim-1 inhibitor 2 is a potent Pim-1 inhibitor (Ki = 91 nM) that targets the ATP-binding kinase hinge region.[Cayman Chemical]
Uses
Pim-1 Inhibitor 2 acts as a serione/threonine kinase targeting proteins involved in cell proliferation and survical. Potential anti-tumor agent.
IC 50
PIM1: 91 nM (Ki)
4-[3-(4-Chlorophenyl)-2,1-benzisoxazol-5-yl]-2-pyrimidinamine Preparation Products And Raw materials
Raw materials
Preparation Products
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4-[3-(4-Chlorophenyl)-2,1-benzisoxazol-5-yl]-2-pyrimidinamine Suppliers
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