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CAY10583

Product Name
CAY10583
CAS No.
862891-27-8
Chemical Name
CAY10583
Synonyms
CAY10583;CAY10583 Exclusive;IUJTVDNJFPZYBL-UHFFFAOYSA-N;4'-((N-phenylpentanamido)methyl)-[1,1'-biphenyl]-2-carboxylic acid;4'-[[(1-Oxopentyl)phenylamino]methyl]-[1,1'-biphenyl]-2-carboxylic acid;[1,1'-Biphenyl]-2-carboxylic acid, 4'-[[(1-oxopentyl)phenylamino]methyl]-;4′-[[(1-oxopentyl)phenylamino]methyl]-[1,1′-biphenyl]-2-carboxylic acid, CAS 862891-27-8
CBNumber
CB02590431
Molecular Formula
C25H25NO3
Formula Weight
387.4709
MOL File
862891-27-8.mol
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CAY10583 Property

Boiling point:
562.0±43.0 °C(Predicted)
Density 
1.177±0.06 g/cm3(Predicted)
storage temp. 
Store at -20°C
solubility 
DMF: 10 mg/ml; DMF:PBS (pH 7.2) (1:9): 0.1 mg/ml; DMSO: 10 mg/ml; Ethanol: 0.25 mg/ml
form 
A crystalline solid
pka
3.84±0.36(Predicted)
color 
white to beige
InChI
InChI=1S/C25H25NO3/c1-2-3-13-24(27)26(21-9-5-4-6-10-21)18-19-14-16-20(17-15-19)22-11-7-8-12-23(22)25(28)29/h4-12,14-17H,2-3,13,18H2,1H3,(H,28,29)
InChIKey
IUJTVDNJFPZYBL-UHFFFAOYSA-N
SMILES
C(O)(=O)C1=CC=CC=C1C1=CC=C(CN(C(=O)CCCC)C2=CC=CC=C2)C=C1
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Cayman Chemical
Product number
10012424
Product name
CAY10583
Purity
≥98%
Packaging
5mg
Price
$61
Updated
2024/03/01
Cayman Chemical
Product number
10012424
Product name
CAY10583
Purity
≥98%
Packaging
10mg
Price
$112
Updated
2024/03/01
Cayman Chemical
Product number
10012424
Product name
CAY10583
Purity
≥98%
Packaging
25mg
Price
$264
Updated
2024/03/01
Cayman Chemical
Product number
10012424
Product name
CAY10583
Purity
≥98%
Packaging
50mg
Price
$468
Updated
2024/03/01
TRC
Product number
E588613
Product name
4''-[[(1-oxopentyl)phenylamino]methyl]-[1,1''-biphenyl]-2-carboxylicAcid
Packaging
10mg
Price
$90
Updated
2021/12/16
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CAY10583 Chemical Properties,Usage,Production

Uses

4''-[[(1-oxopentyl)phenylamino]methyl]-[1,1''-biphenyl]-2-carboxylic acid is a BLT2 agonist.

Definition

ChEBI: [1,1'-biphenyl]-2-carboxylic acid, 4'-[[(1-oxopentyl)phenylamino]methyl]- is a member of biphenyls.

Biological Activity

CAY10583 is a potent and selective full agonist for Leukotriene B4 receptor type 2 (BLT2). CAY10583 promotes wound healing and cell proliferation in cultured intestinal epithelial cells.

in vivo

CAY10583 (administered topically to full-thickness wounds; 10 μM; 14 days) significantly results in a greater wound closure than the control group. The difference in wound closure between the CAY-treated group and the control group is pronounced over time until day 10. And the difference is approximately 6% at day 4 and reaches almost 20% at day 8. Notably, 100% closure was observed in the CAY-treated group at day 14[1].

Animal Model:Lewis rats (6-9 weeks of age, 180-220 g)[1]
Dosage:10 μM; 14 days
Administration:Administered topically to full-thickness wounds; 10 μM; 14 days
Result:Accelerated in vivo wound healing by topical application.

IC 50

BLT2

CAY10583 Preparation Products And Raw materials

Raw materials

Preparation Products

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862891-27-8, CAY10583Related Search:


  • CAY10583
  • 4'-[[(1-Oxopentyl)phenylamino]methyl]-[1,1'-biphenyl]-2-carboxylic acid
  • CAY10583 Exclusive
  • IUJTVDNJFPZYBL-UHFFFAOYSA-N
  • 4'-((N-phenylpentanamido)methyl)-[1,1'-biphenyl]-2-carboxylic acid
  • [1,1'-Biphenyl]-2-carboxylic acid, 4'-[[(1-oxopentyl)phenylamino]methyl]-
  • 4′-[[(1-oxopentyl)phenylamino]methyl]-[1,1′-biphenyl]-2-carboxylic acid, CAS 862891-27-8
  • 862891-27-8