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TAK875

Product Name
TAK875
CAS No.
1374598-80-7
Chemical Name
TAK875
Synonyms
CS-1926;TAK-875（b）;TAK-875(0.5H2O);TAK875 hemihydrate;TAK-875 hymihydrate;(3S)-6-[[2',6'-Dimethyl-4'-[3-(methylsulfonyl)propoxy][1,1'-biphenyl]-3-yl]methoxy]-2,3-dihydro-3-benzofuranacetic acid hydrate (2:1);[(3S)-6-({2',6'-dimethyl-4'-[3-(methylsulfonyl)propoxy]biphe-nyl-3-yl}meth-oxy)-2,3-dihydro-1-benzofuran-3-yl]acetic acid hemi-hydrate;TAK875 (3S)-6-[[2',6'-Dimethyl-4'-[3-(methylsulfonyl)propoxy][1,1'-biphenyl]-3-yl]methoxy]-2,3-dihydro-3-benzofuranacetic acid
CBNumber
CB02660082
Molecular Formula
C58H66O15S2
Formula Weight
1067.26564
MOL File
1374598-80-7.mol
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TAK875 Property

storage temp. 
Store at -20°C
solubility 
DMSO: 100 mg/mL (187.40 mM);Ethanol: Insoluble
Water Solubility 
Water: Insoluble
InChI
InChI=1S/2C29H32O7S.H2O/c2*1-19-12-25(34-10-5-11-37(3,32)33)13-20(2)29(19)22-7-4-6-21(14-22)17-35-24-8-9-26-23(15-28(30)31)18-36-27(26)16-24;/h2*4,6-9,12-14,16,23H,5,10-11,15,17-18H2,1-3H3,(H,30,31);1H2/t2*23-;/m11./s1
InChIKey
OJXYMYYDAVXPIK-IWKNALKQSA-N
SMILES
S(C([H])([H])[H])(C([H])([H])C([H])([H])C([H])([H])OC1C([H])=C(C([H])([H])[H])C(=C(C([H])([H])[H])C=1[H])C1=C([H])C([H])=C([H])C(=C1[H])C([H])([H])OC1C([H])=C([H])C2=C(C=1[H])OC([H])([H])[C@@]2([H])C([H])([H])C(=O)O[H])(=O)=O.S(C([H])([H])[H])(C([H])([H])C([H])([H])C([H])([H])OC1C([H])=C(C([H])([H])[H])C(=C(C([H])([H])[H])C=1[H])C1=C([H])C([H])=C([H])C(=C1[H])C([H])([H])OC1C([H])=C([H])C2=C(C=1[H])OC([H])([H])[C@@]2([H])C([H])([H])C(=O)O[H])(=O)=O.O([H])[H]
CAS DataBase Reference
1374598-80-7
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Crysdot
Product number
CD31003704
Product name
Fasiglifamhemihydrate
Purity
95+%
Packaging
100mg
Price
$600
Updated
2021/12/16
Crysdot
Product number
CD31003704
Product name
Fasiglifamhemihydrate
Purity
95+%
Packaging
250mg
Price
$930
Updated
2021/12/16
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TAK875 Chemical Properties,Usage,Production

Characteristics

More potent at activating hGPR40 than oleic acid

Biological Activity

TAK-875 is a selective GPR40 agonist with EC50 of 14 nM, 400-fold more potent than oleic acid.

target

< td style="border-bottom: 1px dotted #ccc;padding: 5px;"> 14 nM(EC50)
TargetValue
GPR40
(CHO cells expressing human GPR40)

TAK875 Preparation Products And Raw materials

Raw materials

Preparation Products

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TAK875 Suppliers

China 34 United States 5 Global 39
Wuhan ariel chemical Co., LTD.
Tel
18986259541 18986259541
Fax
027-87840182
Email
sales@3stc.com
Country
China
ProdList
4001
Advantage
58
The future of Shanghai Industrial Co., Ltd.
Tel
021-61552785
Fax
021-55660885
Email
sales@shshiji.com
Country
China
ProdList
9545
Advantage
55
Wuhan Kaymke Chemical Co., Ltd.,
Tel
027-027-87342388 18086026008
Fax
027-87342388
Email
sales@kaymke.com
Country
China
ProdList
3874
Advantage
55
Shanghai HuanChuan Industry Co.,Ltd.
Tel
021-61478794
Fax
021-61478794
Email
sales@hcshhai.com
Country
China
ProdList
9793
Advantage
50
Credit Asia Chemical Co., Ltd.
Tel
+86 (21) 61124340
Fax
+86 (21) 6129-4103
Country
China
ProdList
9756
Advantage
58
Shanghai Lollane Biological Technology Co.,Ltd.
Tel
021-52996696，15000506266 15000506266
Fax
+86-21-52996696
Country
China
ProdList
4512
Advantage
55
Codow Chemical Co.,Ltd.
Tel
18620099427
Fax
+86-20-62619665
Email
amy@howeipharm.com
Country
China
ProdList
17687
Advantage
55
Target molecule Corp.
Tel
857-239-0968
Fax
857-239-8801
Email
service1@targetmol.com
Country
United States
ProdList
2559
Advantage
60
Shanghai Rechem science Co., Ltd.
Tel
21-31433387 15618786686
Fax
QQ:1369748377
Email
sales@rechemscience.com
Country
China
ProdList
2990
Advantage
58
Amadis Chemical Company Limited
Tel
571-89925085
Fax
0086-571-89925065
Email
sales@amadischem.com
Country
China
ProdList
131957
Advantage
58

1374598-80-7, TAK875Related Search:

TAK875 Y27632 (hydrochloride) Vorinostat Carfilzomib SCH772984 CHIR-99021 Olaparib

  • [(3S)-6-({2',6'-dimethyl-4'-[3-(methylsulfonyl)propoxy]biphe-nyl-3-yl}meth-oxy)-2,3-dihydro-1-benzofuran-3-yl]acetic acid hemi-hydrate
  • TAK875 (3S)-6-[[2',6'-Dimethyl-4'-[3-(methylsulfonyl)propoxy][1,1'-biphenyl]-3-yl]methoxy]-2,3-dihydro-3-benzofuranacetic acid
  • TAK-875(0.5H2O)
  • CS-1926
  • (3S)-6-[[2',6'-Dimethyl-4'-[3-(methylsulfonyl)propoxy][1,1'-biphenyl]-3-yl]methoxy]-2,3-dihydro-3-benzofuranacetic acid hydrate (2:1)
  • TAK875 hemihydrate
  • TAK-875 hymihydrate
  • TAK-875（b）
  • 1374598-80-7
  • 2C29H32O7SH2O
  • C29H32O7S12H2O
  • API
  • Inhibitors