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DMA

Product Name
DMA
CAS No.
188860-26-6
Chemical Name
DMA
Synonyms
DMA, 10 mM in DMSO;2,5'-Bi-1H-benzimidazole, 2'-(3,4-dimethoxyphenyl)-5-(4-methyl-1-piperazinyl)-;2'-(3,4-Dimethoxyphenyl)-5-(4-methylpiperazin-1-yl)-1H,1'H-2,5'-bibenzo[d]imidazole
CBNumber
CB02666620
Molecular Formula
C27H28N6O2
Formula Weight
468.55
MOL File
188860-26-6.mol
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DMA Property

Melting point:
220 °C
Boiling point:
737.3±70.0 °C(Predicted)
Density 
1.292±0.06 g/cm3(Predicted)
storage temp. 
2-8°C
solubility 
DMSO : ≥ 54 mg/mL (115.25 mM);
form 
Powder
pka
10.78±0.10(Predicted)
color 
Light brown to brown
Appearance
Solid Powder
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

American Custom Chemicals Corporation
Product number
INB0004947
Product name
DMA
Purity
95.00%
Packaging
5MG
Price
$457.19
Updated
2021/12/16
Crysdot
Product number
CD47000060
Product name
DMA
Purity
98+%
Packaging
50mg
Price
$168
Updated
2021/12/16
Crysdot
Product number
CD47000060
Product name
DMA
Purity
98+%
Packaging
100mg
Price
$224
Updated
2021/12/16
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DMA Chemical Properties,Usage,Production

Description

DMA is a fluorescent dye used for staining DNA.

Uses

DMA is a fluorescent compound (λex=340 nm, λem=478 nm).

Biological Activity

DMA is a fluorescent compound (λex=340 nm, λem=478 nm).

in vitro

The newly synthesized bisbenzimidazole derivatives DMA (6c) is evaluated for their cytotoxicity against human tumor cell lines, which are cervix carcinoma cell line (HeLa), breast carcinoma cell line (MCF7) and brain glioma cell line (U87 ) in comparison to Hoechst. In case of MCF7, the IC 50 is observed at 5.3 μM for DMA. The IC 50 determined in the case of HeLa is 3.4 μM for DMA .

target

IC50: 3.4 μM (HeLa cell), 5.3 μM (MCF7 cell)

References

[1] Singh M, et al. Synthesis and biological activity of novel inhibitors of topoisomerase I: 2-aryl-substituted 2-bis-1H-benzimidazoles. Eur J Med Chem. 2011 Feb;46(2):659-69. DOI:10.1016/j.ejmech.2010.11.046

DMA Preparation Products And Raw materials

Raw materials

Preparation Products

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DMA Suppliers

China 28 United States 6 Global 34
MedChemexpress LLC
Tel
021-58955995
Fax
609-228-5909
Email
sales@medchemexpress.cn
Country
United States
ProdList
4861
Advantage
58
AdooQ BioScience, LLC
Tel
+1 (866) 930-6790
Fax
+1 (866) 333-9607
Email
info@adooq.com
Country
United States
ProdList
2782
Advantage
58
Musechem
Tel
+1-800-259-7612
Fax
+1-800-259-7612
Email
info@musechem.com
Country
United States
ProdList
4660
Advantage
60
TargetMol Chemicals Inc.
Tel
+1-781-999-5354; +17819995354
Email
marketing@targetmol.com
Country
United States
ProdList
32435
Advantage
58
Aladdin Scientific
Tel
Email
tp@aladdinsci.com
Country
United States
ProdList
57505
Advantage
58
MedChemExpress
Tel
--
Fax
--
Email
sales@medchemexpress.com
Country
United States
ProdList
6398
Advantage
58

188860-26-6, DMARelated Search:


  • 2,5'-Bi-1H-benzimidazole, 2'-(3,4-dimethoxyphenyl)-5-(4-methyl-1-piperazinyl)-
  • 2'-(3,4-Dimethoxyphenyl)-5-(4-methylpiperazin-1-yl)-1H,1'H-2,5'-bibenzo[d]imidazole
  • DMA, 10 mM in DMSO
  • 188860-26-6