(+)-XESTOSPONGIN B

Product Name: (+)-XESTOSPONGIN B
CAS No.: 123000-02-2
Chemical Name: (+)-XESTOSPONGIN B
Synonyms: Araguspongin B;ARAGUSPONGINE B;(+)-XESTOSPONGIN B;PQYOPBRFUUEHRC-BRAZDTPBSA-N;5H,17H-1,23:11,13-Diethano-2H,14H-[1,11]dioxacycloeicosino[2,3-b:12,13-b']dipyridine, eicosahydro-, (1R,4aR,11S,12aR,13R,16aR,23S,24aR)- (9CI);[1R-(1R*,4AR*,11S*,12AR*,13R*,16AR*,23S*,24AR*)]-EICOSAHYDRO-5H,17H-1,23:11,13-DIETHANO-2H,14H-[1,11]DIOXACYCLOEICOSINO[2,3-B:12,13-B'] DIPYRIDINE
CBNumber: CB0268244
Molecular Formula: C28H50N2O2
Formula Weight: 446.71
MOL File: 123000-02-2.mol

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(+)-XESTOSPONGIN B Property

Boiling point:: 564.7±35.0 °C(Predicted)
Density: 1.05±0.1 g/cm3(Predicted)
solubility: See Below: See Notes Below
form: A clear film
pka: 7.73±0.20(Predicted)

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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Cayman Chemical

Product number: 10006797
Product name: Araguspongin B
Purity: ≥90%
Packaging: 100μg
Price: $398
Updated: 2024/03/01

Cayman Chemical

Product number: 10006797
Product name: Araguspongin B
Purity: ≥90%
Packaging: 250μg
Price: $943
Updated: 2024/03/01

AHH

Product number: MT-22552
Product name: (+)-Xestospongin B
Purity: 90%
Packaging: 0.25g
Price: $230
Updated: 2021/12/16

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(+)-XESTOSPONGIN B Chemical Properties,Usage,Production

Uses

Xestospongins and araguspongins are marine natural products first isolated from Pacific basin sponges, and noted to have vasodilatory properties.1 Inositol phosphates (IP) are important signal transduction messengers acting via IP3 receptors to promote the mobilization of Ca2+ from intracellular stores.2 Araguspongin B antagonizes the calcium-releasing action of inositol 1,4,5-trisphosphate at the receptor level in cerebral microsomes, with an IC50 of 0.6 μM. It is nearly as potent as xestospongin C as an antagonist of the IP3 receptor.

References

[1] Majerus, et al. Inositol phosphate biochemistry. Annu. Rev. Biochem. 61, 225-250 (1992).

(+)-XESTOSPONGIN B Preparation Products And Raw materials

Raw materials

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123000-02-2, (+)-XESTOSPONGIN BRelated Search:

(+)-XESTOSPONGIN A Xestospongin D, Xestospongia sp. XESTOSPONGIN,XESTOSPONGIN C Xestospongin C**Do not take new orders, alternative 682162** XESTOSPONGIN D, XESTOSPONGIA SPECIES,XESTOSPONGIN D (+)-XESTOSPONGIN B

(+)-XESTOSPONGIN B

Araguspongin B

ARAGUSPONGINE B

[1R-(1R*,4AR*,11S*,12AR*,13R*,16AR*,23S*,24AR*)]-EICOSAHYDRO-5H,17H-1,23:11,13-DIETHANO-2H,14H-[1,11]DIOXACYCLOEICOSINO[2,3-B:12,13-B'] DIPYRIDINE

PQYOPBRFUUEHRC-BRAZDTPBSA-N

5H,17H-1,23:11,13-Diethano-2H,14H-[1,11]dioxacycloeicosino[2,3-b:12,13-b']dipyridine, eicosahydro-, (1R,4aR,11S,12aR,13R,16aR,23S,24aR)- (9CI)

123000-02-2

C29H52N2O3