C12-Sphingosine
- Product Name
- C12-Sphingosine
- CAS No.
- 128427-86-1
- Chemical Name
- C12-Sphingosine
- Synonyms
- C12-Sphingosine;Sphingosine (d12:1);(2S,3R,E)-2-Aminododec-4-ene-1,3-diol;4-Dodecene-1,3-diol, 2-amino-, (2S,3R,4E)-
- CBNumber
- CB02708771
- Molecular Formula
- C12H25NO2
- Formula Weight
- 215.33
- MOL File
- 128427-86-1.mol
C12-Sphingosine Property
- Boiling point:
- 364.8±42.0 °C(Predicted)
- Density
- 0.980±0.06 g/cm3(Predicted)
- solubility
- DMF: 10 mg/mL; DMSO: 2 mg/ml; Ethanol: miscible
- form
- A crystalline solid
- pka
- 11.83±0.45(Predicted)
- color
- White to off-white
N-Bromosuccinimide Price
- Product number
- 26893
- Product name
- Sphingosine (d12:1)
- Packaging
- 500μg
- Price
- $63
- Updated
- 2024/03/01
- Product number
- 26893
- Product name
- Sphingosine (d12:1)
- Packaging
- 1mg
- Price
- $117
- Updated
- 2024/03/01
- Product number
- 26893
- Product name
- Sphingosine (d12:1)
- Purity
- ≥95%
- Packaging
- 5mg
- Price
- $396
- Updated
- 2024/03/01
- Product number
- S680720
- Product name
- C12-Sphingosine
- Packaging
- 100mg
- Price
- $1540
- Updated
- 2021/12/16
- Product number
- 72396
- Product name
- C12-Sphingosine
- Packaging
- 100mg
- Price
- $2400
- Updated
- 2021/12/16
C12-Sphingosine Chemical Properties,Usage,Production
Description
Sphingosine (d12:1) is a short-chain sphingolipid. It decreases serine palmitoyltransferase activity in primary cultured mouse cerebellar cells in a concentration-dependent manner. Sphingosine (d12:1) (0.5-50 μM) decreases production of sphingosine (d18:1) , lactosylceramide (Item Nos. 27197 | 16983), galactosylceramide , and a variety of gangliosides in mouse cerebellar granule cells. [Matreya, LLC. Catalog No. 1838]
Uses
(2S,3R,4E)-2-Amino-4-dodecene-1,3-diol acts as a sphingolipid base that inhibits sphingosine kinase.
References
[1] E C MANDON. Sphingolipid biosynthesis in cultured neurons. Down-regulation of serine palmitoyltransferase by sphingoid bases.[J]. European journal of biochemistry, 1991, 198 3: 667-674. DOI: 10.1111/j.1432-1033.1991.tb16065.x
[2] G. ECHTEN. Modulation of sphingolipid biosynthesis in primary cultured neurons by long chain bases.[J]. The Journal of Biological Chemistry, 1990, 120 1: 9333-9339. DOI: 10.1016/s0021-9258(19)38853-2
C12-Sphingosine Preparation Products And Raw materials
Raw materials
Preparation Products
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