KUC103479N-02

Product Name: KUC103479N-02
CAS No.: 1222513-26-9
Chemical Name: KUC103479N-02
Synonyms: KSC-221-15;CID44216842;KUC103479N-02;CID44216842 ，S6000;CID44216842 >=98% (HPLC);CID44216842, 10 mM in DMSO;CID44216842 (Synonyms: Cdc42-IN-1);4-[3-(4-Bromophenyl)-5-(3-methoxyphenyl)-3,4-dihydropyrazol-2-yl]benzenesulfonamide;4-(5-(4-Bromophenyl)-3-(3-methoxyphenyl)-4,5-dihydro-1H-pyrazol-1-yl)benzenesulfonamide;4-[5-(4-bromophenyl)-4,5-dihydro-3-(3-methoxyphenyl)-1H-pyrazol-1-yl]-benzenesulfonamide
CBNumber: CB02751085
Molecular Formula: C22H20BrN3O3S
Formula Weight: 486.38
MOL File: 1222513-26-9.mol

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KUC103479N-02 Property

storage temp.: 2-8°C
solubility: DMSO: soluble20mg/mL, clear
form: powder
color: white to beige

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Safety

Hazard Codes: Xi
Risk Statements: 36/37/38
Safety Statements: 26
WGK Germany: 3

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: SML0918
Product name: CID44216842
Purity: ≥98% (HPLC)
Packaging: 25mg
Price: $417
Updated: 2025/07/31

ChemScene

Product number: CS-0128857
Product name: CID44216842
Purity: 99.84%
Packaging: 5mg
Price: $100
Updated: 2021/12/16

ChemScene

Product number: CS-0128857
Product name: CID44216842
Purity: 99.84%
Packaging: 10mg
Price: $170
Updated: 2021/12/16

ChemScene

Product number: CS-0128857
Product name: CID44216842
Purity: 99.84%
Packaging: 25mg
Price: $350
Updated: 2021/12/16

ChemScene

Product number: CS-0128857
Product name: CID44216842
Purity: 99.84%
Packaging: 50mg
Price: $550
Updated: 2021/12/16

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KUC103479N-02 Chemical Properties,Usage,Production

Uses

CID44216842 (Cdc42-IN-1) is a potent Cdc42-selective guanine nucleotide binding lead inhibitor. The EC50s for Cdc42 WT and Cdc42Q61L mutant are 1.0 and 1.2 μM in GTP binding assay, respectively. The EC50s for Cdc42 WT and Cdc42Q61L mutant are 0.3 and 0.5 μM in GDP binding assay, respectively. Use as a molecular probe[1].

Biological Activity

CID44216842 is a potent and selective non-competitive allosteric inhibitor of Cdc42 GTPase th at does not inhabit Rho and Rac. CID44216842 inhibits Cdc42 dependent filopodia formation and cell migration.

References

[1] Lin Hong, et al. Characterization of a Cdc42 Protein Inhibitor and Its Use as a Molecular Probe. J Biol Chem. 2013 Mar 22;288(12):8531-43. DOI:10.1074/jbc.M112.435941

KUC103479N-02 Preparation Products And Raw materials

Raw materials

Preparation Products

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KUC103479N-02 Suppliers

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1222513-26-9, KUC103479N-02Related Search:

4-[3-(4-Bromophenyl)-5-(3-methoxyphenyl)-3,4-dihydropyrazol-2-yl]benzenesulfonamide

CID44216842

KSC-221-15

KUC103479N-02

Benzenesulfonamide, 4-[5-(4-bromophenyl)-4,5-dihydro-3-(3-methoxyphenyl)-1H-pyrazol-1-yl]-

CID44216842 >=98% (HPLC)

4-(5-(4-Bromophenyl)-3-(3-methoxyphenyl)-4,5-dihydro-1H-pyrazol-1-yl)benzenesulfonamide

diseases,neutrophils,ovarian,disorders,Cdc42,fibroblasts,breast,hepatitis C,CID 44216842,retardation,Inhibitor,CID44216842,Ras,cancer,kidney epithelia,mental,inhibit,immune,virus,neurological,CID-44216842

4-[5-(4-bromophenyl)-4,5-dihydro-3-(3-methoxyphenyl)-1H-pyrazol-1-yl]-benzenesulfonamide

CID44216842, 10 mM in DMSO

CID44216842 (Synonyms: Cdc42-IN-1)

CID44216842 ，S6000

1222513-26-9