KUC103479N-02
- Product Name
- KUC103479N-02
- CAS No.
- 1222513-26-9
- Chemical Name
- KUC103479N-02
- Synonyms
- KSC-221-15;CID44216842;KUC103479N-02;CID44216842 ，S6000;CID44216842 >=98% (HPLC);CID44216842, 10 mM in DMSO;CID44216842 (Synonyms: Cdc42-IN-1);4-[3-(4-Bromophenyl)-5-(3-methoxyphenyl)-3,4-dihydropyrazol-2-yl]benzenesulfonamide;4-(5-(4-Bromophenyl)-3-(3-methoxyphenyl)-4,5-dihydro-1H-pyrazol-1-yl)benzenesulfonamide;4-[5-(4-bromophenyl)-4,5-dihydro-3-(3-methoxyphenyl)-1H-pyrazol-1-yl]-benzenesulfonamide
- CBNumber
- CB02751085
- Molecular Formula
- C22H20BrN3O3S
- Formula Weight
- 486.38
- MOL File
- 1222513-26-9.mol
KUC103479N-02 Property
- storage temp.
- 2-8°C
- solubility
- DMSO: soluble20mg/mL, clear
- form
- powder
- color
- white to beige
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P271Use only outdoors or in a well-ventilated area.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- SML0918
- Product name
- CID44216842
- Purity
- ≥98% (HPLC)
- Packaging
- 25mg
- Price
- $417
- Updated
- 2025/07/31
- Product number
- CS-0128857
- Product name
- CID44216842
- Purity
- 99.84%
- Packaging
- 5mg
- Price
- $100
- Updated
- 2021/12/16
- Product number
- CS-0128857
- Product name
- CID44216842
- Purity
- 99.84%
- Packaging
- 10mg
- Price
- $170
- Updated
- 2021/12/16
- Product number
- CS-0128857
- Product name
- CID44216842
- Purity
- 99.84%
- Packaging
- 25mg
- Price
- $350
- Updated
- 2021/12/16
- Product number
- CS-0128857
- Product name
- CID44216842
- Purity
- 99.84%
- Packaging
- 50mg
- Price
- $550
- Updated
- 2021/12/16
KUC103479N-02 Chemical Properties,Usage,Production
Uses
CID44216842 (Cdc42-IN-1) is a potent Cdc42-selective guanine nucleotide binding lead inhibitor. The EC50s for Cdc42 WT and Cdc42Q61L mutant are 1.0 and 1.2 μM in GTP binding assay, respectively. The EC50s for Cdc42 WT and Cdc42Q61L mutant are 0.3 and 0.5 μM in GDP binding assay, respectively. Use as a molecular probe[1].
Biological Activity
CID44216842 is a potent and selective non-competitive allosteric inhibitor of Cdc42 GTPase th at does not inhabit Rho and Rac. CID44216842 inhibits Cdc42 dependent filopodia formation and cell migration.
References
[1] Lin Hong, et al. Characterization of a Cdc42 Protein Inhibitor and Its Use as a Molecular Probe. J Biol Chem. 2013 Mar 22;288(12):8531-43. DOI:10.1074/jbc.M112.435941
KUC103479N-02 Preparation Products And Raw materials
Raw materials
Preparation Products
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