InterleukinF
Description Source Background- Product Name
- InterleukinF
- Chemical Name
- InterleukinF
- Synonyms
- IL17F;IL17 A/F;InterleukinF;IL-17F human;IL-17A/F human;Interleukin-17 AF;Interleukin-17 A/F
- CBNumber
- CB02915322
- Formula Weight
- 0
- MOL File
- Mol file
InterleukinF Property
- storage temp.
- -20°C
N-Bromosuccinimide Price
- Product number
- 396425
- Product name
- IL-17 F
- Packaging
- 48Tests
- Price
- $588
- Updated
- 2021/12/16
- Product number
- 352926
- Product name
- IL-17F
- Packaging
- 96Tests
- Price
- $719
- Updated
- 2021/12/16
- Product number
- 472342
- Product name
- IL-17AF
- Packaging
- 96Tests
- Price
- $731
- Updated
- 2021/12/16
- Product number
- 472349
- Product name
- IL-17F
- Packaging
- 96Tests
- Price
- $731
- Updated
- 2021/12/16
- Product number
- 472341
- Product name
- IL-17AF
- Packaging
- 96Tests
- Price
- $731
- Updated
- 2021/12/16
InterleukinF Chemical Properties,Usage,Production
Description
IL-17A/F Human Recombinant produced in E.Coli is a heterodimeric, non-glycosylated polypeptide chain containing 1 monomeric subunit of each IL-17A & IL-17F. The active dimer contains 271 amino acids and having a total molecular mass of 30.7 kDa.
The IL-17A/F Human is purified by proprietary chromatographic techniques.
Source
Escherichia Coli
Background
IL-17F having an accession number of Q96PD4 is a cytokine that shares sequence similarity with IL17. IL-17F is expressed by activated T cells, and has been shown to stimulate the production of several other cytokines, including IL6, IL8, and CSF2/GM_CSF. IL-17F inhibits the angiogenesis of endothelial cells and induce endothelial cells to produce IL2, TGFB1/TGFB, and monocyte chemoattractant protein-1. IL-17F induces stromal cells to produce proinflammatory and hematopoietic cytokines. Intestinal IL17F gene expression is increased in active CD.
IL-17A & IL-17F alleles influence the susceptibility to and pathophysiological features of ulcerative colitis independently. IL-17F and MIF gene polymorphisms are significantly associated with the development of functional dyspepsia.
The initiation of IL-17F/IL-17R signaling pathway requires the receptor ubiquitination by TRAF6. IL-17F induces expression of IFN-gamma-inducible protein 10 (IP-10) by activating Raf1-mitogen-activated protein kinase 1/2-extracellular-regulated kinase 1/2-p90 ribosomal S6 kinase-cyclic AMP response element-binding protein signaling pathway.
InterleukinF Preparation Products And Raw materials
Raw materials
Preparation Products
InterleukinF Suppliers
- Tel
- --
- Fax
- --
- sales@advtechind.com
- Country
- United States
- ProdList
- 6075
- Advantage
- 58
- Tel
- --
- Fax
- --
- Country
- United States
- ProdList
- 6773
- Advantage
- 87