ChemicalBook > CAS DataBase List > CNGRCGGKLAKLAKKLAKLAK-NH2 (DISULFIDE BRIDGE: 1-5)
CNGRCGGKLAKLAKKLAKLAK-NH2 (DISULFIDE BRIDGE: 1-5)
- Product Name
- CNGRCGGKLAKLAKKLAKLAK-NH2 (DISULFIDE BRIDGE: 1-5)
- CAS No.
- 1926163-30-5
- Chemical Name
- CNGRCGGKLAKLAKKLAKLAK-NH2 (DISULFIDE BRIDGE: 1-5)
- Synonyms
- NGR PEPTIDE 1;NGR Peptide 1 - 1 mg;CNGRCGGKLAKLAKKLAKLAK-NH2;TUMOR TARGETED PRO-APOPTOTIC PEPTIDE;CNGRC-GG-(KLAKLAK)2-NH2 (DISULFIDE BOND);CNGRCGGKLAKLAKKLAKLAK-NH2 (DISULFIDE BOND);CNGRCGGKLAKLAKKLAKLAK-NH2 (DISULFIDE BRIDGE: 1-5);Tumor Targeted Pro-Apoptotic Peptide、NGR Peptide 1;CNGRCGGklaklakklaklak-NH2 (Disulfide bond), CNGRC-GG-(klaklak)2-NH2 (Disulfide bond);CYS-ASN-GLY-ARG-CYS-GLY-GLY-DLYS-DLEU-DALA-DLYS-DLEU-DALA-DLYS-DLYS-DLEU-DALA-DLYS-DLEU-DALA-DLYS
- CBNumber
- CB0314341
- Molecular Formula
- C94H174N32O22S2
- Formula Weight
- 2168.72
- MOL File
- Mol file
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CNGRCGGKLAKLAKKLAKLAK-NH2 (DISULFIDE BRIDGE: 1-5) Property
- Density
- 1.42±0.1 g/cm3(Predicted)
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N-Bromosuccinimide Price
American Custom Chemicals Corporation
- Product number
- PEP0002667
- Product name
- NGR PEPTIDE 1
- Purity
- 95.00%
- Packaging
- 1MG
- Price
- $806.48
- Updated
- 2021/12/16
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CNGRCGGKLAKLAKKLAKLAK-NH2 (DISULFIDE BRIDGE: 1-5) Chemical Properties,Usage,Production
Uses
Tumor targeted pro-apoptotic peptide (CNGRC-GG-D(KLAKLAK)2) is an anti-tumor peptide. Tumor targeted pro-apoptotic peptide disrupts mitochondrial membranes and promotes apoptosis, showing anticancer activity in mice[1].
in vivo
Tumor targeted pro-apoptotic peptide inhibits both primary tumor growth and metastasis in mice[1].
| Animal Model: | Tumor targeted pro-apoptotic peptide (250 μg/mice; tail vein injection; 250 μg a week for 17 weeks) inhibits both primary tumor growth and metastasis in mice[1]. |
| Dosage: | 250 μg/mice |
| Administration: | Tail vein injection; 250 μg a week for 17 weeks |
| Result: | Exhibited antitumor activity in vivo. |
References
[1] Ellerby HM, et al. Anti-cancer activity of targeted pro-apoptotic peptides. Nat Med. 1999 Sep;5(9):1032-8. DOI:10.1038/12469
CNGRCGGKLAKLAKKLAKLAK-NH2 (DISULFIDE BRIDGE: 1-5) Preparation Products And Raw materials
Raw materials
Preparation Products
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CNGRCGGKLAKLAKKLAKLAK-NH2 (DISULFIDE BRIDGE: 1-5) Suppliers
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