ChemicalBook > CAS DataBase List > 5-(2-Methoxy-4-(((2-(tetrahydro-2H-pyran-4-yl)ethyl)amino)methyl)phenoxy)pyrazine-2-carboxamide

5-(2-Methoxy-4-(((2-(tetrahydro-2H-pyran-4-yl)ethyl)amino)methyl)phenoxy)pyrazine-2-carboxamide

Product Name
5-(2-Methoxy-4-(((2-(tetrahydro-2H-pyran-4-yl)ethyl)amino)methyl)phenoxy)pyrazine-2-carboxamide
CAS No.
676500-67-7
Chemical Name
5-(2-Methoxy-4-(((2-(tetrahydro-2H-pyran-4-yl)ethyl)amino)methyl)phenoxy)pyrazine-2-carboxamide
Synonyms
Bevenopran;2-PYRAZINECARBOXAMIDE, 5-[2-METHOXY-4-[[[2-(TETRAHYDRO-2H-PYRAN-4-YL)ETHYL]AMINO]METHYL]PHENOXY]-;CB-5945;ADL-5945;Bevenopran, 10 mM in DMSO;Inhibitor,CB 5945,Bevenopran,CB5945,inhibit,Opioid Receptor,ADL 5945,ADL5945;5-[2-methoxy-4-[[2-(oxan-4-yl)ethylamino]methyl]phenoxy]pyrazine-2-carboxamide;5-(2-Methoxy-4-(((2-(tetrahydro-2H-pyran-4-yl)ethyl)amino)methyl)phenoxy)pyrazine-2-carboxamide
CBNumber
CB03161690
Molecular Formula
C20H26N4O4
Formula Weight
386.44
MOL File
676500-67-7.mol
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5-(2-Methoxy-4-(((2-(tetrahydro-2H-pyran-4-yl)ethyl)amino)methyl)phenoxy)pyrazine-2-carboxamide Property

Melting point:
133 - 136 °C
Boiling point:
575.0±50.0 °C(Predicted)
Density 
1.204±0.06 g/cm3(Predicted)
storage temp. 
Refrigerator, under inert atmosphere
solubility 
Acetonitrile (Slightly), Chloroform (Slightly)
pka
14.06±0.50(Predicted)
form 
Solid
color 
White to Off-White
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

TRC
Product number
B335005
Product name
Bevenopran
Packaging
10mg
Price
$50
Updated
2021/12/16
Chemenu
Product number
CM254476
Product name
5-(2-Methoxy-4-(((2-(tetrahydro-2H-pyran-4-yl)ethyl)amino)methyl)phenoxy)pyrazine-2-carboxamide
Purity
95%+
Packaging
1g
Price
$234
Updated
2021/12/16
Crysdot
Product number
CD11074155
Product name
5-(2-Methoxy-4-(((2-(tetrahydro-2H-pyran-4-yl)ethyl)amino)methyl)phenoxy)pyrazine-2-carboxamide
Purity
95+%
Packaging
1g
Price
$248
Updated
2021/12/16
Alichem
Product number
676500677
Product name
5-(2-Methoxy-4-(((2-(tetrahydro-2H-pyran-4-yl)ethyl)amino)methyl)phenoxy)pyrazine-2-carboxamide
Packaging
1g
Price
$272.5
Updated
2021/12/16
Chemenu
Product number
CM254476
Product name
5-(2-Methoxy-4-(((2-(tetrahydro-2H-pyran-4-yl)ethyl)amino)methyl)phenoxy)pyrazine-2-carboxamide
Purity
95%+
Packaging
5g
Price
$701
Updated
2021/12/16
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5-(2-Methoxy-4-(((2-(tetrahydro-2H-pyran-4-yl)ethyl)amino)methyl)phenoxy)pyrazine-2-carboxamide Chemical Properties,Usage,Production

Uses

Bevenopran, is a peripheral μ-opioid receptor antagonist.

Definition

ChEBI: Bevenopran is an aromatic ether.

in vivo

Bevenopran is a peripheral μ-opioid receptor antagonist. Bevenopran is currently under investigation for the treatment of opioid-induced bowel dysfunction (OBD)[1]. Bevenopran tends to increase bowel movement (BM) frequency, especially for 0.1 mg twice daily and 4 mg daily, respectively[1].

IC 50

μ Opioid Receptor/MOR

5-(2-Methoxy-4-(((2-(tetrahydro-2H-pyran-4-yl)ethyl)amino)methyl)phenoxy)pyrazine-2-carboxamide Preparation Products And Raw materials

Raw materials

Preparation Products

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5-(2-Methoxy-4-(((2-(tetrahydro-2H-pyran-4-yl)ethyl)amino)methyl)phenoxy)pyrazine-2-carboxamide Suppliers

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View Lastest Price from 5-(2-Methoxy-4-(((2-(tetrahydro-2H-pyran-4-yl)ethyl)amino)methyl)phenoxy)pyrazine-2-carboxamide manufacturers

Zibo Hangyu Biotechnology Development Co., Ltd
Product
Bevenopran 676500-67-7
Price
US $65.00-650.00/kg
Min. Order
10kg
Purity
0.99
Supply Ability
20tons
Release date
2023-10-31

676500-67-7, 5-(2-Methoxy-4-(((2-(tetrahydro-2H-pyran-4-yl)ethyl)amino)methyl)phenoxy)pyrazine-2-carboxamideRelated Search:


  • 5-[2-methoxy-4-[[2-(oxan-4-yl)ethylamino]methyl]phenoxy]pyrazine-2-carboxamide
  • 2-PYRAZINECARBOXAMIDE, 5-[2-METHOXY-4-[[[2-(TETRAHYDRO-2H-PYRAN-4-YL)ETHYL]AMINO]METHYL]PHENOXY]-
  • Bevenopran
  • 5-(2-Methoxy-4-(((2-(tetrahydro-2H-pyran-4-yl)ethyl)amino)methyl)phenoxy)pyrazine-2-carboxamide
  • ADL-5945
  • CB-5945
  • Inhibitor,CB 5945,Bevenopran,CB5945,inhibit,Opioid Receptor,ADL 5945,ADL5945
  • Bevenopran, 10 mM in DMSO
  • 676500-67-7