ChemicalBook > CAS DataBase List > 5-(2-Methoxy-4-(((2-(tetrahydro-2H-pyran-4-yl)ethyl)amino)methyl)phenoxy)pyrazine-2-carboxamide
5-(2-Methoxy-4-(((2-(tetrahydro-2H-pyran-4-yl)ethyl)amino)methyl)phenoxy)pyrazine-2-carboxamide
- Product Name
- 5-(2-Methoxy-4-(((2-(tetrahydro-2H-pyran-4-yl)ethyl)amino)methyl)phenoxy)pyrazine-2-carboxamide
- CAS No.
- 676500-67-7
- Chemical Name
- 5-(2-Methoxy-4-(((2-(tetrahydro-2H-pyran-4-yl)ethyl)amino)methyl)phenoxy)pyrazine-2-carboxamide
- Synonyms
- Bevenopran;2-PYRAZINECARBOXAMIDE, 5-[2-METHOXY-4-[[[2-(TETRAHYDRO-2H-PYRAN-4-YL)ETHYL]AMINO]METHYL]PHENOXY]-;CB-5945;ADL-5945;Bevenopran, 10 mM in DMSO;Inhibitor,CB 5945,Bevenopran,CB5945,inhibit,Opioid Receptor,ADL 5945,ADL5945;5-[2-methoxy-4-[[2-(oxan-4-yl)ethylamino]methyl]phenoxy]pyrazine-2-carboxamide;5-(2-Methoxy-4-(((2-(tetrahydro-2H-pyran-4-yl)ethyl)amino)methyl)phenoxy)pyrazine-2-carboxamide
- CBNumber
- CB03161690
- Molecular Formula
- C20H26N4O4
- Formula Weight
- 386.44
- MOL File
- 676500-67-7.mol
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5-(2-Methoxy-4-(((2-(tetrahydro-2H-pyran-4-yl)ethyl)amino)methyl)phenoxy)pyrazine-2-carboxamide Property
- Melting point:
- 133 - 136 °C
- Boiling point:
- 575.0±50.0 °C(Predicted)
- Density
- 1.204±0.06 g/cm3(Predicted)
- storage temp.
- Refrigerator, under inert atmosphere
- solubility
- Acetonitrile (Slightly), Chloroform (Slightly)
- pka
- 14.06±0.50(Predicted)
- form
- Solid
- color
- White to Off-White
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N-Bromosuccinimide Price
TRC
- Product number
- B335005
- Product name
- Bevenopran
- Packaging
- 10mg
- Price
- $50
- Updated
- 2021/12/16
Chemenu
- Product number
- CM254476
- Product name
- 5-(2-Methoxy-4-(((2-(tetrahydro-2H-pyran-4-yl)ethyl)amino)methyl)phenoxy)pyrazine-2-carboxamide
- Purity
- 95%+
- Packaging
- 1g
- Price
- $234
- Updated
- 2021/12/16
Crysdot
- Product number
- CD11074155
- Product name
- 5-(2-Methoxy-4-(((2-(tetrahydro-2H-pyran-4-yl)ethyl)amino)methyl)phenoxy)pyrazine-2-carboxamide
- Purity
- 95+%
- Packaging
- 1g
- Price
- $248
- Updated
- 2021/12/16
Alichem
- Product number
- 676500677
- Product name
- 5-(2-Methoxy-4-(((2-(tetrahydro-2H-pyran-4-yl)ethyl)amino)methyl)phenoxy)pyrazine-2-carboxamide
- Packaging
- 1g
- Price
- $272.5
- Updated
- 2021/12/16
Chemenu
- Product number
- CM254476
- Product name
- 5-(2-Methoxy-4-(((2-(tetrahydro-2H-pyran-4-yl)ethyl)amino)methyl)phenoxy)pyrazine-2-carboxamide
- Purity
- 95%+
- Packaging
- 5g
- Price
- $701
- Updated
- 2021/12/16
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5-(2-Methoxy-4-(((2-(tetrahydro-2H-pyran-4-yl)ethyl)amino)methyl)phenoxy)pyrazine-2-carboxamide Chemical Properties,Usage,Production
Uses
Bevenopran, is a peripheral μ-opioid receptor antagonist.
Definition
ChEBI: Bevenopran is an aromatic ether.
in vivo
Bevenopran is a peripheral μ-opioid receptor antagonist. Bevenopran is currently under investigation for the treatment of opioid-induced bowel dysfunction (OBD)[1]. Bevenopran tends to increase bowel movement (BM) frequency, especially for 0.1 mg twice daily and 4 mg daily, respectively[1].
IC 50
μ Opioid Receptor/MOR
5-(2-Methoxy-4-(((2-(tetrahydro-2H-pyran-4-yl)ethyl)amino)methyl)phenoxy)pyrazine-2-carboxamide Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from 5-(2-Methoxy-4-(((2-(tetrahydro-2H-pyran-4-yl)ethyl)amino)methyl)phenoxy)pyrazine-2-carboxamide manufacturers
Zibo Hangyu Biotechnology Development Co., Ltd
- Product
- Bevenopran 676500-67-7
- Price
- US $65.00-650.00/kg
- Min. Order
- 10kg
- Purity
- 0.99
- Supply Ability
- 20tons
- Release date
- 2023-10-31