CGP 42112

Product Name: CGP 42112
CAS No.: 127060-75-7
Chemical Name: CGP 42112
Synonyms: CGP 42112;CGP-42112A;CGP 42112 TFA;CGP42112A, CGP42112;CGP-42112 (CGP42112;ANGIOTENSIN II ANTAGONIST;ANGIOTENSIN II RECEPTOR LIGAND;NIC-TYR-LYS(Z-ARG)-HIS-PRO-ILE;CGP 42112, AT2 receptor ligand;CGP-42112A >=95%, synthetic, solid
CBNumber: CB0334084
Molecular Formula: C52H69N13O11
Formula Weight: 1052.18
MOL File: 127060-75-7.mol

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CGP 42112 Property

Density: 1.39±0.1 g/cm3(Predicted)
storage temp.: -20°C
solubility: DMSO:350.0(Max Conc. mg/mL);332.64(Max Conc. mM)
pka: 3.72±0.22(Predicted)
form: solid
color: white
biological source: synthetic
Water Solubility: Soluble to 1 mg/ml in water
BRN: 8184948

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Safety

Safety Statements: 22-24/25
WGK Germany: 3
F: 10

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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: C160
Product name: CGP-42112A
Purity: ≥95%, synthetic, solid
Packaging: 1mg
Price: $164.4
Updated: 2024/03/01

Sigma-Aldrich

Product number: C160
Product name: CGP-42112A
Purity: ≥95%, synthetic, solid
Packaging: 5mg
Price: $978
Updated: 2024/03/01

Tocris

Product number: 2569
Product name: CGP42112
Packaging: 1
Price: $193
Updated: 2021/12/16

Usbiological

Product number: 254938
Product name: CGP 42112
Packaging: 1mg
Price: $446
Updated: 2021/12/16

ChemScene

Product number: CS-3414
Product name: CGP-42112
Purity: 99.02%
Packaging: 5mg
Price: $535
Updated: 2021/12/16

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CGP 42112 Chemical Properties,Usage,Production

Uses

CGP-42112A has been used:

in the isolation of RNA from fibroblast-like synoviocytes from rheumatoid arthritis patients (RA-FLS)
to study its effects on the ERK2 phosphorylation in the cardiomyoblast cell line
as a stimulator of angiotensin II type 2 (AT2) receptor to study its effects on human regional hemodynamic responses mediated by AT2 receptors

Definition

ChEBI: CGP-42112A is a hexapeptide consisting of L-tyrosine, L-lysine, L-histidine, L-proline and L-isoleucine amino acid residues coupled in sequence and in which the amino group of the L-tyrosyl residue is substituted by a (pyridin-3-ylcarbonyl)nitrilo group and in which the L-lysyl side chain amino group is substituted by a {N(2)-[(benzyloxy)carbonyl]-L-arginyl}nitrilo group. It is a potent angiotensin II receptor type 2 (AT2 receptor) agonist. It has a role as an angiotensin receptor agonist, a vasodilator agent, an antineoplastic agent, an anti-inflammatory agent and a neuroprotective agent. It is an oligopeptide, a benzyl ester and a pyridinecarboxamide.

Biochem/physiol Actions

Potent AT2 angiotensin II receptor agonist.

storage

Store at -20°C

CGP 42112 Preparation Products And Raw materials

Raw materials

Preparation Products

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CGP 42112 Suppliers

China 71 France 1 Germany 1 Japan 1 Switzerland 1 United Kingdom 2 United States 14 Global 91

3B Pharmachem (Wuhan) International Co.,Ltd.

Tel: 821-50328103-801 18930552037
Fax: 86-21-50328109
Email: 3bsc@sina.com
Country: China
ProdList: 15839
Advantage: 69

GL Biochem (Shanghai) Ltd

Tel: 21-61263452 13641803416
Fax: 86-21-61263399
Email: ymbetter@glbiochem.com
Country: China
ProdList: 9981
Advantage: 64

Shanghai Hanhong Scientific Co.,Ltd.

Tel: 021-54306202 13764082696
Email: info@hanhongsci.com
Country: China
ProdList: 42958
Advantage: 64

Chemsky（shanghai）International Co.,Ltd.

Tel: 021-50135380
Email: shchemsky@sina.com
Country: China
ProdList: 32321
Advantage: 50

Haoyuan Chemexpress Co., Ltd.

Tel: 021-58950125
Fax: (86) 21-58955996
Email: info@chemexpress.com
Country: China
ProdList: 7552
Advantage: 61

Wuxi Zhongkun Biochemical Technology Co., Ltd.

Tel: 0510-85629785 18013409632
Fax: 051085625359
Email: sales@reading-chemicals.com
Country: China
ProdList: 15178
Advantage: 58

LETOPHARM LIMITED

Tel: +86-21-5821 5861
Fax: +86-21-5106 2861
Email: sales@letopharm.com
Country: China
ProdList: 2384
Advantage: 58

Sigma-Aldrich

Tel: 021-61415566 800-8193336
Email: orderCN@merckgroup.com
Country: China
ProdList: 51456
Advantage: 80

Creative Peptides

Tel
Email: info@creative-peptides.com
Country: United States
ProdList: 6083
Advantage: 56

Guangzhou QiYun Biotechnology Co., Ltd.

Tel: 020-61288194 61288195
Fax: 020-61288700
Email: 505721671@qq.com
Country: China
ProdList: 3866
Advantage: 58

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View Lastest Price from CGP 42112 manufacturers

Career Henan Chemical Co

Product: CGP 42112 127060-75-7
Price: US $7.00/KG
Min. Order: 1KG
Purity: 99%
Supply Ability: 100kg
Release date: 2020-02-13

127060-75-7, CGP 42112Related Search:

CGP 42112A, [125I]- SG 1842 Lys-His-Gly-NH2 Glycylglycyl-L-isoleucine CGP 42112A, [3-(125I)-TYR] Phenatine H-PRO-VAL-OH 2-PHENYL-N-(PYRIDIN-3-YLMETHYL)ETHANAMINE CHEMBRDG-BB 5402672 CGP 42112 (2S)-1-[(2S)-2-Amino-3-(3H-imidazol-4-yl)propanoyl]pyrrolidine-2-carboxamide H-PRO-ILE-OH CHEMBRDG-BB 9071485 (6-Aminohexyl)carbamic acid

[N-ALPHA-(NICOTINOYL-L-TYROSYL)-N-EPSILON-(N-ALPHA-Z-L-ARGINYL)-L-LYSYL]-L HISTIDYL-L-PROLYL-L-ISOLEUCINE

N-ALPHA-NICOTINOYL-TYR-LYS(N-ALPHA-CBZ-ARG)-HIS-PRO-ILE

N-ALPHA-NICOTINOYL-TYR-(N-ALPHA-CBZ-ARG)-LYS-HIS-PRO-ILE-OH

NICOTINOYL-TYR-LYS(CBZ-ARG)-HIS-PRO-ILE

NICOTINOYL-TYR-LYS(Z-ARG)-HIS-PRO-ILE-OH

NIC-TYR-LYS(Z-ARG)-HIS-PRO-ILE

CGP 42112

CGP-42112A

Angiotensin II Receptor Ligand Nicotinoyl-Tyr-Lys(Z-Arg)-His-Pro-Ile-OH

ANGIOTENSIN II ANTAGONIST

ANGIOTENSIN II RECEPTOR LIGAND

CGP-42112A >98% SYNTHETIC (POTENTANGIOTE NSIN II TYPE A

N-NICOTINOYL-TYR-N-EPSILON(NA-CBZ-ARG)-L YS-HIS-PRO

nα-nicotinoyl-tyr-(nα-cbz-arg)-lys-his-pro-ile

N6-[[(Phenylmethoxy)carbonyl]-L-Arg-]-N2-[[(pyridin-3-yl)carbonyl]-L-Tyr-]-L-Lys-L-His-L-Pro-L-Ile-OH

CGP 42112;NΑ-NICOTINOYL-TYR-(NΑ-CBZ-ARG)-LYS-HIS-PRO-ILE

CGP42112A, CGP42112

CGP42112;CGP 42112;CGP-42112A;CGP42112A;CGP 42112A

CGP-42112 (CGP42112

L-Isoleucine, N-(3-pyridinylcarbonyl)-L-tyrosyl-N6-[N2-[(phenylmethoxy)carbonyl]-L-arginyl]-L-lysyl-L-histidyl-L-prolyl-

CGP-42112A >=95%, synthetic, solid

(2S,3S)-2-((S)-1-((5S,12S,15S)-15-((1H-Imidazol-5-yl)methyl)-5-(3-guanidinopropyl)-12-((S)-3-(4-hydroxyphenyl)-2-(nicotinamido)propanamido)-3,6,13-trioxo-1-phenyl-2-oxa-4,7,14-triazahexadecan-16-oyl)pyrrolidine-2-carboxamido)-3-methylpentanoic acid

CGP 42112 TFA

CGP 42112, AT2 receptor ligand

127060-75-7

C52H69N13O11

Biochemicals and Reagents

Angiotensins

Amino Acids and Peptides

BioChemical

Peptides