ChemicalBook > CAS DataBase List > CHOLIC-2,2,4,4-D4 ACID

CHOLIC-2,2,4,4-D4 ACID

Product Name
CHOLIC-2,2,4,4-D4 ACID
CAS No.
116380-66-6
Chemical Name
CHOLIC-2,2,4,4-D4 ACID
Synonyms
Cholic-d4 Acid;2H4]-Cholic Acid;Cholic acid-2,2,4,4-d;Cholic Acid -[d4] (Solution);Cholic Acid-d4 MaxSpec? Standard;CHOLICACID(2,2,4,4-D4) IN METHANOL;5β-cholanic acid-3α,7α,12α-triol-2,2,4,4-d4;CHOLIC ACID (2,2,4,4-D4, 98%) 100 UG/ML IN METHANOL
CBNumber
CB0334837
Molecular Formula
C24H36D4O5
Formula Weight
412.6
MOL File
116380-66-6.mol
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CHOLIC-2,2,4,4-D4 ACID Property

Melting point:
200-201°C (lit.)
storage temp. 
Store at -20°C
solubility 
DMF: 30 mg/ml,DMF:PBS(pH 7.2)(1:1): 0.5 mg/ml,DMSO: 20 mg/ml,Ethanol: 20 mg/ml
form 
Solid
color 
White to Off-White
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Safety

WGK Germany 
3
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Danger
Hazard statements

H225Highly Flammable liquid and vapour

H370Causes damage to organs

Precautionary statements

P210Keep away from heat/sparks/open flames/hot surfaces. — No smoking.

P233Keep container tightly closed.

P240Ground/bond container and receiving equipment.

P241Use explosion-proof electrical/ventilating/lighting/…/equipment.

P242Use only non-sparking tools.

P243Take precautionary measures against static discharge.

P260Do not breathe dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P303+P361+P353IF ON SKIN (or hair): Remove/Take off Immediately all contaminated clothing. Rinse SKIN with water/shower.

P307+P311IF exposed: call a POISON CENTER or doctor/physician.

P321Specific treatment (see … on this label).

P370+P378In case of fire: Use … for extinction.

P403+P235Store in a well-ventilated place. Keep cool.

P405Store locked up.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
614149
Product name
Cholic acid-2,2,4,4-d
Purity
98 atom % D, 98% (CP)
Packaging
500mg
Price
$1670
Updated
2024/03/01
Cayman Chemical
Product number
20849
Product name
Cholic Acid-d4
Purity
≥95%
Packaging
1mg
Price
$81
Updated
2024/03/01
Cayman Chemical
Product number
20849
Product name
Cholic Acid-d4
Purity
≥95%
Packaging
5mg
Price
$120
Updated
2024/03/01
Cayman Chemical
Product number
20849
Product name
Cholic Acid-d4
Purity
≥95%
Packaging
10mg
Price
$223
Updated
2024/03/01
TRC
Product number
C432603
Product name
CholicAcid-d4
Packaging
50mg
Price
$470
Updated
2021/12/16
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CHOLIC-2,2,4,4-D4 ACID Chemical Properties,Usage,Production

Description

Cholic acid-d4 is intended for use as an internal standard for the quantification of cholic acid by GC- or LC-MS. Cholic acid is a primary bile acid. It is formed from cholesterol via a multistep process catalyzed by the cytochrome P450 (CYP) isoforms CYP7A1, CYP8B1, and CYP27A1. Cholic acid is conjugated to glycine or taurine by bile acid-CoA:amino acid N-acyltransferase (BAAT) to produce glycocholic acid (GCA; ) and taurocholic acid (TCA; ), respectively, in the liver, and is transformed into the secondary bile acid deoxycholic acid (DCA; ) by intestinal microbiota. It induces C. difficile colony formation in an agar dilution assay when used at a concentration of 0.1% w/v. Dietary administration of cholic acid (0.4% w/w) increases serum cholesterol levels, biliary phospholipid secretion, and fecal DCA levels in rats.

Uses

Cholic Acid-d4 is a labelled analog of Cholic acid (C432600) which is a choleretic produced by, and isolated from liver cells.

Definition

ChEBI: Cholic acid-2,2,4,4-d4 is a bile acid.

CHOLIC-2,2,4,4-D4 ACID Preparation Products And Raw materials

Raw materials

Preparation Products

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CHOLIC-2,2,4,4-D4 ACID Suppliers

ChemeGen(Shanghai) Biotechnology Co.,Ltd.
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021-67187366 19901745723
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021-58000709 15900491054
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TianJin Alta Scientific Co., Ltd.
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116380-66-6, CHOLIC-2,2,4,4-D4 ACIDRelated Search:


  • Cholic-d4 Acid
  • Cholic acid-2,2,4,4-d
  • 5β-cholanic acid-3α,7α,12α-triol-2,2,4,4-d4
  • CHOLIC ACID (2,2,4,4-D4, 98%) 100 UG/ML IN METHANOL
  • Cholic Acid -[d4] (Solution)
  • Cholic Acid-d4 MaxSpec? Standard
  • 2H4]-Cholic Acid
  • CHOLICACID(2,2,4,4-D4) IN METHANOL
  • 116380-66-6
  • C24H36D4O5
  • Steroids & Hormones - 13C & 2H