CHOLIC-2,2,4,4-D4 ACID
- Product Name
- CHOLIC-2,2,4,4-D4 ACID
- CAS No.
- 116380-66-6
- Chemical Name
- CHOLIC-2,2,4,4-D4 ACID
- Synonyms
- Cholic-d4 Acid;2H4]-Cholic Acid;Cholic acid-2,2,4,4-d;Cholic Acid -[d4] (Solution);Cholic Acid-d4 MaxSpec? Standard;CHOLICACID(2,2,4,4-D4) IN METHANOL;5β-cholanic acid-3α,7α,12α-triol-2,2,4,4-d4;CHOLIC ACID (2,2,4,4-D4, 98%) 100 UG/ML IN METHANOL
- CBNumber
- CB0334837
- Molecular Formula
- C24H36D4O5
- Formula Weight
- 412.6
- MOL File
- 116380-66-6.mol
CHOLIC-2,2,4,4-D4 ACID Property
- Melting point:
- 200-201°C (lit.)
- storage temp.
- Store at -20°C
- solubility
- DMF: 30 mg/ml,DMF:PBS(pH 7.2)(1:1): 0.5 mg/ml,DMSO: 20 mg/ml,Ethanol: 20 mg/ml
- form
- Solid
- color
- White to Off-White
Safety
- WGK Germany
- 3
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Danger
- Hazard statements
-
H225Highly Flammable liquid and vapour
H370Causes damage to organs
- Precautionary statements
-
P210Keep away from heat/sparks/open flames/hot surfaces. — No smoking.
P233Keep container tightly closed.
P240Ground/bond container and receiving equipment.
P241Use explosion-proof electrical/ventilating/lighting/…/equipment.
P242Use only non-sparking tools.
P243Take precautionary measures against static discharge.
P260Do not breathe dust/fume/gas/mist/vapours/spray.
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P270Do not eat, drink or smoke when using this product.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P303+P361+P353IF ON SKIN (or hair): Remove/Take off Immediately all contaminated clothing. Rinse SKIN with water/shower.
P307+P311IF exposed: call a POISON CENTER or doctor/physician.
P321Specific treatment (see … on this label).
P370+P378In case of fire: Use … for extinction.
P403+P235Store in a well-ventilated place. Keep cool.
P405Store locked up.
P501Dispose of contents/container to..…
N-Bromosuccinimide Price
- Product number
- 614149
- Product name
- Cholic acid-2,2,4,4-d
- Purity
- 98 atom % D, 98% (CP)
- Packaging
- 500mg
- Price
- $1670
- Updated
- 2024/03/01
- Product number
- 20849
- Product name
- Cholic Acid-d4
- Purity
- ≥95%
- Packaging
- 1mg
- Price
- $81
- Updated
- 2024/03/01
- Product number
- 20849
- Product name
- Cholic Acid-d4
- Purity
- ≥95%
- Packaging
- 5mg
- Price
- $120
- Updated
- 2024/03/01
- Product number
- 20849
- Product name
- Cholic Acid-d4
- Purity
- ≥95%
- Packaging
- 10mg
- Price
- $223
- Updated
- 2024/03/01
- Product number
- C432603
- Product name
- CholicAcid-d4
- Packaging
- 50mg
- Price
- $470
- Updated
- 2021/12/16
CHOLIC-2,2,4,4-D4 ACID Chemical Properties,Usage,Production
Description
Cholic acid-d4 is intended for use as an internal standard for the quantification of cholic acid by GC- or LC-MS. Cholic acid is a primary bile acid. It is formed from cholesterol via a multistep process catalyzed by the cytochrome P450 (CYP) isoforms CYP7A1, CYP8B1, and CYP27A1. Cholic acid is conjugated to glycine or taurine by bile acid-CoA:amino acid N-acyltransferase (BAAT) to produce glycocholic acid (GCA; ) and taurocholic acid (TCA; ), respectively, in the liver, and is transformed into the secondary bile acid deoxycholic acid (DCA; ) by intestinal microbiota. It induces C. difficile colony formation in an agar dilution assay when used at a concentration of 0.1% w/v. Dietary administration of cholic acid (0.4% w/w) increases serum cholesterol levels, biliary phospholipid secretion, and fecal DCA levels in rats.
Uses
Cholic Acid-d4 is a labelled analog of Cholic acid (C432600) which is a choleretic produced by, and isolated from liver cells.
Definition
ChEBI: Cholic acid-2,2,4,4-d4 is a bile acid.
CHOLIC-2,2,4,4-D4 ACID Preparation Products And Raw materials
Raw materials
Preparation Products
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