ChemicalBook > CAS DataBase List > 1-(4-(Aminomethyl)benzyl)-2-butyl-1H-imidazo[4,5-c]quinolin-4-amine dihydrochloride
1-(4-(Aminomethyl)benzyl)-2-butyl-1H-imidazo[4,5-c]quinolin-4-amine dihydrochloride
- Product Name
- 1-(4-(Aminomethyl)benzyl)-2-butyl-1H-imidazo[4,5-c]quinolin-4-amine dihydrochloride
- CAS No.
- 1620278-72-9
- Chemical Name
- 1-(4-(Aminomethyl)benzyl)-2-butyl-1H-imidazo[4,5-c]quinolin-4-amine dihydrochloride
- Synonyms
- TLR7/8 agonist-5d;TLR7/8 agonist 1 2HCl;8 agonist 1 dihydrochloride;TLR7/8 Agonist 1 (hydrochloride);TLR7/8 Agonist 5d (hydrochloride);TLR7/8 agonist 1 (dihydrochloride);1-(4-(Aminomethyl)benzyl)-2-butyl-1H-imidazo[4,5-c]quinolin-4-amine dihydrochloride;Toll-like Receptor (TLR),TLR7/8 agonist 1,TLR7/8 agonist 1 dihydrochloride,TLR-7/8 agonist 1 dihydrochloride,Inhibitor,inhibit
- CBNumber
- CB03374339
- Molecular Formula
- C22H26ClN5
- Formula Weight
- 395.94
- MOL File
- 1620278-72-9.mol
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1-(4-(Aminomethyl)benzyl)-2-butyl-1H-imidazo[4,5-c]quinolin-4-amine dihydrochloride Property
- storage temp.
- Store at -20°C
- solubility
- DMSO:83.33(Max Conc. mg/mL);192.72(Max Conc. mM)
- form
- A solid
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N-Bromosuccinimide Price
Cayman Chemical
- Product number
- 28451
- Product name
- TLR7/8 Agonist 1 (hydrochloride)
- Packaging
- 500μg
- Price
- $73
- Updated
- 2024/03/01
Cayman Chemical
- Product number
- 28451
- Product name
- TLR7/8 Agonist 1 (hydrochloride)
- Packaging
- 5mg
- Price
- $468
- Updated
- 2024/03/01
Cayman Chemical
- Product number
- 28451
- Product name
- TLR7/8 Agonist 1 (hydrochloride)
- Packaging
- 1mg
- Price
- $131
- Updated
- 2024/03/01
AK Scientific
- Product number
- 3353EB
- Product name
- TLR7/8agonist1(dihydrochloride)
- Packaging
- 1mg
- Price
- $243
- Updated
- 2021/12/16
ChemScene
- Product number
- CS-0032947
- Product name
- TLR7/8agonist1(dihydrochloride)
- Purity
- 98.47%
- Packaging
- 10mg
- Price
- $550
- Updated
- 2021/12/16
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1-(4-(Aminomethyl)benzyl)-2-butyl-1H-imidazo[4,5-c]quinolin-4-amine dihydrochloride Chemical Properties,Usage,Production
Biological Activity
TLR7/8 agonist 1 dihydrochloride is a dual agonist of the toll-like receptor TLR7/TLR8.
in vitro
TLR7/8 agonist 1 (Compound 5d) shows prominent immunostimulatory activities. TLR7/8 agonist 1 serves as a convenient precursor for the covalent attachment of fluorophores without significant loss of activity.It retains TLR7- agonistic activity with an EC 50 of 20 nM. TLR7/8 agonist 1 (Compound 1) shows substantially different agonistic potencies in human TLR7 (50 nM) and TLR8 (55 nM) primary screens.
target
TLR7/TLR8
1-(4-(Aminomethyl)benzyl)-2-butyl-1H-imidazo[4,5-c]quinolin-4-amine dihydrochloride Preparation Products And Raw materials
Raw materials
Preparation Products
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