ChemicalBook > CAS DataBase List > N-(3R)-1-Azabicyclo[2.2.2]oct-3-yl-5,6,7,8-tetrahydro-1-naphthalenecarboxamide

N-(3R)-1-Azabicyclo[2.2.2]oct-3-yl-5,6,7,8-tetrahydro-1-naphthalenecarboxamide

Product Name
N-(3R)-1-Azabicyclo[2.2.2]oct-3-yl-5,6,7,8-tetrahydro-1-naphthalenecarboxamide
CAS No.
1374226-74-0
Chemical Name
N-(3R)-1-Azabicyclo[2.2.2]oct-3-yl-5,6,7,8-tetrahydro-1-naphthalenecarboxamide
Synonyms
Palonosetron Impurity 21;(R)-N-(quinuclidin-3-yl)-5,6,7,8-tetrahydronaphthalene-1-carboxamide;N-(3R)-1-Azabicyclo[2.2.2]oct-3-yl-5,6,7,8-tetrahydro-1-naphthalenecarboxamide;1-Naphthalenecarboxamide, N-(3R)-1-azabicyclo[2.2.2]oct-3-yl-5,6,7,8-tetrahydro-;N-[(2R)-4-azabicyclo[2.2.2]octan-2-yl]-5,6,7,8-tetrahydronaphthalene-1-carboxamide
CBNumber
CB03480595
Molecular Formula
C18H24N2O
Formula Weight
284.4
MOL File
1374226-74-0.mol
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N-(3R)-1-Azabicyclo[2.2.2]oct-3-yl-5,6,7,8-tetrahydro-1-naphthalenecarboxamide Property

Melting point:
157-159oC
storage temp. 
Refrigerator
solubility 
Chloroform (Slightly), DMSO (Slightly), Methanol (Slightly)
form 
Solid
color 
Pale Beige
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

TRC
Product number
A795315
Product name
N-(3R)-1-Azabicyclo[2.2.2]oct-3-yl-5,6,7,8-tetrahydro-1-naphthalenecarboxamide
Packaging
25mg
Price
$150
Updated
2021/12/16
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N-(3R)-1-Azabicyclo[2.2.2]oct-3-yl-5,6,7,8-tetrahydro-1-naphthalenecarboxamide Chemical Properties,Usage,Production

Uses

N-(3R)-1-Azabicyclo[2.2.2]oct-3-yl-5,6,7,8-tetrahydro-1-naphthalenecarboxamide is an intermediate in the synthesis of Palonosteron (P165805), an serotonin 5-HT3 receptor antagonist used in the prevention and treatment of chemotherapy-induced nausea and vomiting.

N-(3R)-1-Azabicyclo[2.2.2]oct-3-yl-5,6,7,8-tetrahydro-1-naphthalenecarboxamide Preparation Products And Raw materials

Raw materials

Preparation Products

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N-(3R)-1-Azabicyclo[2.2.2]oct-3-yl-5,6,7,8-tetrahydro-1-naphthalenecarboxamide Suppliers

Shanghai Kewel Chemical Co., Ltd.
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Nanjing wangzhixing Pharmaceutical Technology Co., Ltd
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Molcoo Chemicals Inc.
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Hubei Moco Chemical Co., Ltd.
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Moxin Chemicals
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1374226-74-0, N-(3R)-1-Azabicyclo[2.2.2]oct-3-yl-5,6,7,8-tetrahydro-1-naphthalenecarboxamideRelated Search:


  • N-(3R)-1-Azabicyclo[2.2.2]oct-3-yl-5,6,7,8-tetrahydro-1-naphthalenecarboxamide
  • Palonosetron Impurity 21
  • 1-Naphthalenecarboxamide, N-(3R)-1-azabicyclo[2.2.2]oct-3-yl-5,6,7,8-tetrahydro-
  • N-[(2R)-4-azabicyclo[2.2.2]octan-2-yl]-5,6,7,8-tetrahydronaphthalene-1-carboxamide
  • (R)-N-(quinuclidin-3-yl)-5,6,7,8-tetrahydronaphthalene-1-carboxamide
  • 1374226-74-0