DSP-2230

Product Name: DSP-2230
CAS No.: 1233231-30-5
Chemical Name: DSP-2230
Synonyms: DSP-2230;DSP-2230, 10 mM in DMSO;DSP2230; DSP 2230; DSP-2230;Inhibitor,inhibit,Na+ channels,Sodium Channel,DSP 2230,Na channels,DSP2230,DSP-2230;(2S)-2-({[3-cyclobutyl-5-(3,4,5-trifluorophenoxy)-3H-imidazo[4,5-b]pyridin-2-yl]methyl}amino)propanamide;Propanamide, 2-[[[3-cyclobutyl-5-(3,4,5-trifluorophenoxy)-3H-imidazo[4,5-b]pyridin-2-yl]methyl]amino]-, (2S)-
CBNumber: CB05417694
Molecular Formula: C20H20F3N5O2
Formula Weight: 419.4
MOL File: 1233231-30-5.mol

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DSP-2230 Property

Boiling point:: 607.8±55.0 °C(Predicted)
Density: 1.53±0.1 g/cm3(Predicted)
storage temp.: Store at -20°C
solubility: DMSO:125.0(Max Conc. mg/mL);298.04(Max Conc. mM)
form: Solid
pka: 15.94±0.50(Predicted)
color: White to off-white
InChIKey: HHXCJIMPEJSJTG-JTQLQIEISA-N
SMILES: C(N)(=O)[C@@H](NCC1=NC2=CC=C(OC3=CC(F)=C(F)C(F)=C3)N=C2N1C1CCC1)C

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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

ChemScene

Product number: CS-0089255
Product name: DSP-2230
Purity: 98.33%
Packaging: 5mg
Price: $120
Updated: 2021/12/16

ChemScene

Product number: CS-0089255
Product name: DSP-2230
Purity: 98.33%
Packaging: 10mg
Price: $200
Updated: 2021/12/16

ChemScene

Product number: CS-0089255
Product name: DSP-2230
Purity: 98.33%
Packaging: 25mg
Price: $400
Updated: 2021/12/16

ChemScene

Product number: CS-0089255
Product name: DSP-2230
Purity: 98.33%
Packaging: 50mg
Price: $650
Updated: 2021/12/16

ChemScene

Product number: CS-0089255
Product name: DSP-2230
Purity: 98.33%
Packaging: 100mg
Price: $1050
Updated: 2021/12/16

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DSP-2230 Chemical Properties,Usage,Production

Uses

DSP-2230 is a selective Nav1.7/Nav1.8 blocker, can be used to improve neuropathic pain[1][2][3].

IC 50

Nav1.7; Nav1.8

References

[1] Bagal SK, et al. Voltage gated sodium channels as drug discovery targets. Channels (Austin). 2015;9(6):360-6. DOI:10.1080/19336950.2015.1079674
[2] Sara Sabina Hadida-Ruah, et al. Sulfonamides as modulators of sodium channels.
[3] Matthew Alsaloum, et al. Status of peripheral sodium channel blockers for non-addictive pain treatment. Nat Rev Neurol. 2020 Dec;16(12):689-705. DOI:10.1038/s41582-020-00415-2

DSP-2230 Preparation Products And Raw materials

Raw materials

Preparation Products

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DSP-2230 Suppliers

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1233231-30-5, DSP-2230Related Search:

DSP-2230

DSP2230; DSP 2230; DSP-2230

Inhibitor,inhibit,Na+ channels,Sodium Channel,DSP 2230,Na channels,DSP2230,DSP-2230

Propanamide, 2-[[[3-cyclobutyl-5-(3,4,5-trifluorophenoxy)-3H-imidazo[4,5-b]pyridin-2-yl]methyl]amino]-, (2S)-

(2S)-2-({[3-cyclobutyl-5-(3,4,5-trifluorophenoxy)-3H-imidazo[4,5-b]pyridin-2-yl]methyl}amino)propanamide

DSP-2230, 10 mM in DMSO

1233231-30-5