ChemicalBook > CAS DataBase List > DSP-2230

DSP-2230

Product Name
DSP-2230
CAS No.
1233231-30-5
Chemical Name
DSP-2230
Synonyms
DSP-2230;DSP-2230, 10 mM in DMSO;DSP2230; DSP 2230; DSP-2230;Inhibitor,inhibit,Na+ channels,Sodium Channel,DSP 2230,Na channels,DSP2230,DSP-2230;(2S)-2-({[3-cyclobutyl-5-(3,4,5-trifluorophenoxy)-3H-imidazo[4,5-b]pyridin-2-yl]methyl}amino)propanamide;Propanamide, 2-[[[3-cyclobutyl-5-(3,4,5-trifluorophenoxy)-3H-imidazo[4,5-b]pyridin-2-yl]methyl]amino]-, (2S)-
CBNumber
CB05417694
Molecular Formula
C20H20F3N5O2
Formula Weight
419.4
MOL File
1233231-30-5.mol
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DSP-2230 Property

Boiling point:
607.8±55.0 °C(Predicted)
Density 
1.53±0.1 g/cm3(Predicted)
storage temp. 
Store at -20°C
solubility 
DMSO:125.0(Max Conc. mg/mL);298.04(Max Conc. mM)
form 
Solid
pka
15.94±0.50(Predicted)
color 
White to off-white
InChIKey
HHXCJIMPEJSJTG-JTQLQIEISA-N
SMILES
C(N)(=O)[C@@H](NCC1=NC2=CC=C(OC3=CC(F)=C(F)C(F)=C3)N=C2N1C1CCC1)C
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

ChemScene
Product number
CS-0089255
Product name
DSP-2230
Purity
98.33%
Packaging
5mg
Price
$120
Updated
2021/12/16
ChemScene
Product number
CS-0089255
Product name
DSP-2230
Purity
98.33%
Packaging
10mg
Price
$200
Updated
2021/12/16
ChemScene
Product number
CS-0089255
Product name
DSP-2230
Purity
98.33%
Packaging
25mg
Price
$400
Updated
2021/12/16
ChemScene
Product number
CS-0089255
Product name
DSP-2230
Purity
98.33%
Packaging
50mg
Price
$650
Updated
2021/12/16
ChemScene
Product number
CS-0089255
Product name
DSP-2230
Purity
98.33%
Packaging
100mg
Price
$1050
Updated
2021/12/16
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DSP-2230 Chemical Properties,Usage,Production

Uses

DSP-2230 is a selective Nav1.7/Nav1.8 blocker, can be used to improve neuropathic pain[1][2][3].

IC 50

Nav1.7; Nav1.8

References

[1] Bagal SK, et al. Voltage gated sodium channels as drug discovery targets. Channels (Austin). 2015;9(6):360-6. DOI:10.1080/19336950.2015.1079674
[2] Sara Sabina Hadida-Ruah, et al. Sulfonamides as modulators of sodium channels.
[3] Matthew Alsaloum, et al. Status of peripheral sodium channel blockers for non-addictive pain treatment. Nat Rev Neurol. 2020 Dec;16(12):689-705. DOI:10.1038/s41582-020-00415-2

DSP-2230 Preparation Products And Raw materials

Raw materials

Preparation Products

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DSP-2230 Suppliers

TargetMol Chemicals Inc.
Tel
+1-781-999-5354; +17819995354
Email
marketing@targetmol.com
Country
United States
ProdList
32435
Advantage
58
InvivoChem
Tel
+1-708-310-1919 +1-13798911105
Fax
708-557-7486
Email
sales@invivochem.cn
Country
United States
ProdList
6391
Advantage
58
Aladdin Scientific
Tel
Email
tp@aladdinsci.com
Country
United States
ProdList
52923
Advantage
58

1233231-30-5, DSP-2230Related Search:


  • DSP-2230
  • DSP2230; DSP 2230; DSP-2230
  • Inhibitor,inhibit,Na+ channels,Sodium Channel,DSP 2230,Na channels,DSP2230,DSP-2230
  • Propanamide, 2-[[[3-cyclobutyl-5-(3,4,5-trifluorophenoxy)-3H-imidazo[4,5-b]pyridin-2-yl]methyl]amino]-, (2S)-
  • (2S)-2-({[3-cyclobutyl-5-(3,4,5-trifluorophenoxy)-3H-imidazo[4,5-b]pyridin-2-yl]methyl}amino)propanamide
  • DSP-2230, 10 mM in DMSO
  • 1233231-30-5