MIK-8719

Product Name: MIK-8719
CAS No.: 1382799-40-7
Chemical Name: MIK-8719
Synonyms: MK-8719;MIK-8719;MK-8719 ，S8890;MK-8719, 10 mM in DMSO;MK 8719,inhibit,MK-8719,MK8719,Inhibitor;(3aR,5S,6S,7R,7aR)-5-(Difluoromethyl)-2-(ethylamino)-3a,6,7,7a-tetrahydro-5H-pyrano[3,2-d]thiazole-6,7-diol;5H-Pyrano[3,2-d]thiazole-6,7-diol, 5-(difluoromethyl)-2-(ethylamino)-3a,6,7,7a-tetrahydro-, (3aR,5S,6S,7R,7aR)-
CBNumber: CB05581733
Molecular Formula: C9H14F2N2O3S
Formula Weight: 268.28
MOL File: 1382799-40-7.mol

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MIK-8719 Property

Boiling point:: 431.4±55.0 °C(Predicted)
Density: 1.78±0.1 g/cm3(Predicted)
storage temp.: Store at -20°C
solubility: DMSO : 100 mg/mL (372.74 mM; Need ultrasonic)
pka: 12.72±0.70(Predicted)
form: Solid
color: White to yellow

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Hazard and Precautionary Statements (GHS)

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MIK-8719 Chemical Properties,Usage,Production

Uses

MK-8719 is a highly potent and selective O-GlcNAcase (OGA) inhibitor (Ki=7.9 nM for hOGA) with excellent CNS penetration[1].

in vivo

MK-8719 has excellent intrinsic potency and selectivity, improved P_app, high CNS exposure, good pharmacokinetics, favorable metabolic stability, and robust pharmacodynamic response^[1].

References

[1] Selnick HG, et al. Discovery of MK-8719, a Potent O-GlcNAcase Inhibitor as a Potential Treatment for Tauopathies. J Med Chem. 2019 Sep 29. DOI:10.1021/acs.jmedchem.9b01090

MIK-8719 Preparation Products And Raw materials

Raw materials

Preparation Products

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MIK-8719 Suppliers

China 33 United States 3 Global 36

Shanghai Lollane Biological Technology Co.,Ltd.

Tel: 021-52996696，15000506266 15000506266
Fax: +86-21-52996696
Country: China
ProdList: 4757
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ShangHai Biochempartner Co.,Ltd

Tel: 177-54423994 17754423994
Fax: QQ:2853530913
Email: 2853530910@QQ.com
Country: China
ProdList: 8000
Advantage: 62

Chuzhou KeMail Chemical Technology Co., Ltd

Tel: 0550-5196001 15000891977
Fax: 0550-5196001
Email: wj520wjxby@126.com
Country: China
ProdList: 1944
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TargetMol Chemicals Inc.

Tel: +1-781-999-5354; +17819995354
Email: marketing@targetmol.com
Country: United States
ProdList: 32435
Advantage: 58

Zhejiang J&C Biological Technology Co.,Limited

Tel: +1-2135480471
Email: sales@sarms4muscle.com
Country: China
ProdList: 10473
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ShangHai ChuanQian Chemcial Technique Centre

Tel: 15869524721
Email: 3525679403@qq.com
Country: China
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Nantong Hi-Future Biotechnology Co., Ltd

Tel: 18051384581
Email: sales@chemhifuture.com
Country: China
ProdList: 2995
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JinOu Biomedical (Nanjing) Co., Ltd.

Tel: 13000000000
Fax: jinoupharma@163
Email: jinoupharma@163.com
Country: China
ProdList: 11721
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Bide Pharmatech Ltd.

Tel: 400-1647117 13681763483
Email: product02@bidepharm.com
Country: China
ProdList: 62220
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TargetMol Chemicals Inc.

Tel: 4008200310
Email: marketing@tsbiochem.com
Country: China
ProdList: 24961
Advantage: 58

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View Lastest Price from MIK-8719 manufacturers

ZHENGZHOU JIUYI TIME NEW MATERIALS CO,.LTD

Product: MIK-8719 1382799-40-7
Price: US $2.00-5.00/kg
Min. Order: 1kg
Purity: 99%
Supply Ability: 100kg
Release date: 2025-06-18

1382799-40-7, MIK-8719Related Search:

MIK-8719

MK-8719

5H-Pyrano[3,2-d]thiazole-6,7-diol, 5-(difluoromethyl)-2-(ethylamino)-3a,6,7,7a-tetrahydro-, (3aR,5S,6S,7R,7aR)-

MK 8719,inhibit,MK-8719,MK8719,Inhibitor

(3aR,5S,6S,7R,7aR)-5-(Difluoromethyl)-2-(ethylamino)-3a,6,7,7a-tetrahydro-5H-pyrano[3,2-d]thiazole-6,7-diol

MK-8719, 10 mM in DMSO

MK-8719 ，S8890

1382799-40-7

C9H14F2N2O3S