L-Phenylalanine, N-[(2S)-2-hydroxy-1-oxopropyl]-
- Product Name
- L-Phenylalanine, N-[(2S)-2-hydroxy-1-oxopropyl]-
- CAS No.
- 183241-73-8
- Chemical Name
- L-Phenylalanine, N-[(2S)-2-hydroxy-1-oxopropyl]-
- Synonyms
- N-Lactoyl-Phenylalanine;Lac-Phe-OH;Lac-Phe New;Lac-Phe . acetate;Lactoyl Phenylalanine;N-Lactoylphenylalanine;((S)-2-Hydroxypropanoyl)-L-phe-OH;((S)-2-Hydroxypropanoyl)-L-phenylalanine;N-[(S)-2-Hydroxypropanoyl]-L-phenylalanine;N-[(2S)-2-Hydroxy-1-oxopropyl]-L-phenylalanine
- CBNumber
- CB08083292
- Molecular Formula
- C12H15NO4
- Formula Weight
- 237.25
- MOL File
- 183241-73-8.mol
L-Phenylalanine, N-[(2S)-2-hydroxy-1-oxopropyl]- Property
- Melting point:
- >120oC (dec.)
- Boiling point:
- 505.1±50.0 °C(Predicted)
- Density
- 1.268±0.06 g/cm3(Predicted)
- storage temp.
- -20°C Freezer, Under inert atmosphere
- solubility
- DMSO (Slightly), Methanol (Sparingly, Sonicated)
- form
- Solid
- pka
- 3.56±0.10(Predicted)
- color
- White to Off-White
- biological source
- synthetic
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Danger
- Hazard statements
-
H315Causes skin irritation
H318Causes serious eye damage
- Precautionary statements
-
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P310Immediately call a POISON CENTER or doctor/physician.
P321Specific treatment (see … on this label).
P332+P313IF SKIN irritation occurs: Get medical advice/attention.
N-Bromosuccinimide Price
- Product number
- SMB01375
- Product name
- <i>N</i>-Lactoylphenylalanine
- Purity
- ≥95% (HPLC)
- Packaging
- 10 mg
- Price
- $165
- Updated
- 2025/07/31
L-Phenylalanine, N-[(2S)-2-hydroxy-1-oxopropyl]- Chemical Properties,Usage,Production
Uses
N-Lactoyl-Phenylalanine is a useful intermediate in the preparation of chiral morpholinediones by aminolysis of α-hydroxy esters with α-amino acid salts.
Definition
ChEBI: N-[(S)-lactoyl]-L-phenylalanine is a L-phenylalanine derivative that is L-phenylalanine in which the amino group is replaced by a [(2S)-2-hydroxypropanoyl]amino group. It is a metabolite produced as a result of exercise in mice, racehorses, and humans which suppresses feeding and obesity. It has a role as a human metabolite, a mouse metabolite, a mammalian metabolite and an anti-obesity agent. It is a L-phenylalanine derivative and a N-acyl-L-amino acid. It is a conjugate acid of a N-[(S)-lactoyl]-L-phenylalaninate.
in vivo
N-Lactoyl-Phenylalanine (50 mg/kg, i.p.,once a day for 10 days) specifically suppresses energy intake in obese mice without affecting energy expenditure pathways, and this effect is not observed in lean mice[1].
| Animal Model: | Diet-induced obese (DIO) mice model[1] |
| Dosage: | 50 mg/kg |
| Administration: | Intraperitoneal (i.p.), once a day for 10 days |
| Result: | Resulted in reduced cumulative food intake and reduced body weight compared with control mice. After 10?days, mice treated with N-Lactoyl-Phenylalanine also exhibited improved glucose homeostasis, and reduced adiposity without any changes in the weights of the other organs. |
storage
Room temperature
L-Phenylalanine, N-[(2S)-2-hydroxy-1-oxopropyl]- Preparation Products And Raw materials
Raw materials
Preparation Products
L-Phenylalanine, N-[(2S)-2-hydroxy-1-oxopropyl]- Suppliers
- Tel
- 0551-65326643 18156095617
- Fax
- 0551-65326641
- info@cellmano.com
- Country
- China
- ProdList
- 1010
- Advantage
- 55
- Tel
- 021-65675885 18964387627
- Fax
- 021-65675885
- info@efebio.com
- Country
- China
- ProdList
- 9803
- Advantage
- 58
- Tel
- 021-61312847; 18021002903
- Fax
- QQ:3008007432
- 3008007409@qq.com
- Country
- China
- ProdList
- 71826
- Advantage
- 60
- Tel
- 0571-87213919
- Eric@peptidego.com
- Country
- China
- ProdList
- 7408
- Advantage
- 58
- Tel
- 021-61263389 13524856427
- Fax
- WeChat630417570
- Joetang@glschina.com
- Country
- China
- ProdList
- 10000
- Advantage
- 58
- Tel
- 18501792038 18502138905
- shanpel@anpel.com.cn
- Country
- China
- ProdList
- 9611
- Advantage
- 58
- Tel
- 021-61263455 13167021076
- amy@glschina.com
- Country
- China
- ProdList
- 9737
- Advantage
- 58
- Tel
- 18051384581
- sales@chemhifuture.com
- Country
- China
- ProdList
- 2998
- Advantage
- 58
- Tel
- 400-1647117 13681763483
- product02@bidepharm.com
- Country
- China
- ProdList
- 59936
- Advantage
- 58
- Tel
- 4008200310
- marketing@tsbiochem.com
- Country
- China
- ProdList
- 24961
- Advantage
- 58
- Tel
- 0571-87213919 17306812703
- 3007955328@qq.com
- Country
- China
- ProdList
- 6979
- Advantage
- 58
- Tel
- 021-021-50706066 15221275939
- shenlinxing@macklin.cn
- Country
- China
- ProdList
- 29784
- Advantage
- 58
- Tel
- 17717235263
- cindy.yang@lgcgroup.com
- Country
- China
- ProdList
- 18003
- Advantage
- 58
- Tel
- 021-61734564 13854185395;
- info@easycdmo.com
- Country
- China
- ProdList
- 10024
- Advantage
- 58
- Tel
- 19135651983 19135651206
- 243332738@qq.com
- Country
- China
- ProdList
- 908
- Advantage
- 58
- Tel
- 18299177127
- info@richmanchem.com
- Country
- China
- ProdList
- 3000
- Advantage
- 58
- Tel
- 027-59101766 13125137661
- 2853877621@qq.com
- Country
- China
- ProdList
- 7976
- Advantage
- 58
- Tel
- 18024082417
- market@ubiochem.com
- Country
- China
- ProdList
- 9835
- Advantage
- 58
- Tel
- 15102117276 19921389125
- tech@zzbioco.com
- Country
- China
- ProdList
- 12064
- Advantage
- 58
- Tel
- 0512-56316828 4008675858
- sales1@amateksci.com
- Country
- China
- ProdList
- 6250
- Advantage
- 58
- Tel
- 020-81960175-877 18933936954
- 2853283383@qq.com
- Country
- China
- ProdList
- 11421
- Advantage
- 58
- Tel
- 18003437475
- Fax
- 1-612-656-4400
- rdname@qq.com
- Country
- China
- ProdList
- 6960
- Advantage
- 58
- Tel
- 400-821-026
- Sales@sangon.com
- Country
- China
- ProdList
- 6710
- Advantage
- 58
- Tel
- 800-364-9897
- sales@caymanchem.com
- Country
- China
- ProdList
- 6838
- Advantage
- 58
- Tel
- 21-20338288
- ordercn@merckgroup.com
- Country
- China
- ProdList
- 6394
- Advantage
- 58
- Tel
- 51288865780
- sales@biosynth.com
- Country
- China
- ProdList
- 6051
- Advantage
- 58
- Tel
- 021-58056897 15399714481
- info@zsklab.com
- Country
- China
- ProdList
- 7190
- Advantage
- 58
- Tel
- 025-57672321 13739186949
- Fax
- 025-57672123
- yuanming@huashineltd.com
- Country
- China
- ProdList
- 424
- Advantage
- 58
- Tel
- +86-571-87711850
- market18@leapchem.com
- Country
- China
- ProdList
- 43339
- Advantage
- 58
- Tel
- +undefined18051384581
- sales@chemhifuture.com
- Country
- China
- ProdList
- 3135
- Advantage
- 58
- Tel
- 17765667235
- Country
- CHINA
- ProdList
- 129
- Advantage
- 58
- Tel
- 18675945663
- Country
- CHINA
- ProdList
- 126
- Advantage
- 58
- Tel
- 13587866996
- Country
- CHINA
- ProdList
- 199
- Advantage
- 58
- Tel
- 13826205800
- Country
- CHINA
- ProdList
- 154
- Advantage
- 58
- Tel
- --
- Fax
- --
- info@neobioscience.com
- Country
- CHINA
- ProdList
- 6207
- Advantage
- 58
- Tel
- --
- Fax
- --
- chenjw@absin.cn
- Country
- CHINA
- ProdList
- 6208
- Advantage
- 58
- Tel
- --
- Fax
- --
- Proteintech-CN@ptglab.com
- Country
- CHINA
- ProdList
- 6290
- Advantage
- 58