L-Phenylalanine, N-[(2S)-2-hydroxy-1-oxopropyl]-
- Product Name
- L-Phenylalanine, N-[(2S)-2-hydroxy-1-oxopropyl]-
- CAS No.
- 183241-73-8
- Chemical Name
- L-Phenylalanine, N-[(2S)-2-hydroxy-1-oxopropyl]-
- Synonyms
- N-Lactoyl-Phenylalanine;Lac-Phe-OH;Lac-Phe New;Lac-Phe . acetate;Lactoyl Phenylalanine;N-Lactoylphenylalanine;((S)-2-Hydroxypropanoyl)-L-phe-OH;((S)-2-Hydroxypropanoyl)-L-phenylalanine;N-[(S)-2-Hydroxypropanoyl]-L-phenylalanine;N-[(2S)-2-Hydroxy-1-oxopropyl]-L-phenylalanine
- CBNumber
- CB08083292
- Molecular Formula
- C12H15NO4
- Formula Weight
- 237.25
- MOL File
- 183241-73-8.mol
L-Phenylalanine, N-[(2S)-2-hydroxy-1-oxopropyl]- Property
- Melting point:
- >120oC (dec.)
- Boiling point:
- 505.1±50.0 °C(Predicted)
- Density
- 1.268±0.06 g/cm3(Predicted)
- storage temp.
- -20°C Freezer, Under inert atmosphere
- solubility
- DMSO (Slightly), Methanol (Sparingly, Sonicated)
- form
- Solid
- pka
- 3.56±0.10(Predicted)
- color
- White to Off-White
- biological source
- synthetic
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Danger
- Hazard statements
-
H315Causes skin irritation
H318Causes serious eye damage
- Precautionary statements
-
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P310Immediately call a POISON CENTER or doctor/physician.
P321Specific treatment (see … on this label).
P332+P313IF SKIN irritation occurs: Get medical advice/attention.
N-Bromosuccinimide Price
- Product number
- SMB01375
- Product name
- <i>N</i>-Lactoylphenylalanine
- Purity
- ≥95% (HPLC)
- Packaging
- 10 mg
- Price
- $165
- Updated
- 2025/07/31
L-Phenylalanine, N-[(2S)-2-hydroxy-1-oxopropyl]- Chemical Properties,Usage,Production
Uses
N-Lactoyl-Phenylalanine is a useful intermediate in the preparation of chiral morpholinediones by aminolysis of α-hydroxy esters with α-amino acid salts.
Definition
ChEBI: N-[(S)-lactoyl]-L-phenylalanine is a L-phenylalanine derivative that is L-phenylalanine in which the amino group is replaced by a [(2S)-2-hydroxypropanoyl]amino group. It is a metabolite produced as a result of exercise in mice, racehorses, and humans which suppresses feeding and obesity. It has a role as a human metabolite, a mouse metabolite, a mammalian metabolite and an anti-obesity agent. It is a L-phenylalanine derivative and a N-acyl-L-amino acid. It is a conjugate acid of a N-[(S)-lactoyl]-L-phenylalaninate.
in vivo
N-Lactoyl-Phenylalanine (50 mg/kg, i.p.,once a day for 10 days) specifically suppresses energy intake in obese mice without affecting energy expenditure pathways, and this effect is not observed in lean mice[1].
| Animal Model: | Diet-induced obese (DIO) mice model[1] |
| Dosage: | 50 mg/kg |
| Administration: | Intraperitoneal (i.p.), once a day for 10 days |
| Result: | Resulted in reduced cumulative food intake and reduced body weight compared with control mice. After 10?days, mice treated with N-Lactoyl-Phenylalanine also exhibited improved glucose homeostasis, and reduced adiposity without any changes in the weights of the other organs. |
storage
Room temperature
L-Phenylalanine, N-[(2S)-2-hydroxy-1-oxopropyl]- Preparation Products And Raw materials
Raw materials
Preparation Products
L-Phenylalanine, N-[(2S)-2-hydroxy-1-oxopropyl]- Suppliers
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