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Bupranolol

Product Name
Bupranolol
CAS No.
14556-46-8
Chemical Name
Bupranolol
Synonyms
Bupranol;Bupranolol;Ophtorenin;BRN 2272923;Bupranololum;KL 255Ophtorenin;B 1312; BRN 2272923; BUPRANOLOLUM; KL 255OPHTORENIN;1-(tert-Butylamino)-3-[(6-chloro-m-tolyl)oxy]-2-propanol;1-(tert-Butylamino)-3-(2-chloro-5-methylphenoxy)-2-propanol;(S)-1-(tert-Butylamino)-3-(2-chloro-5-methylphenoxy)-2-propanol
CBNumber
CB11118303
Molecular Formula
C14H22ClNO2
Formula Weight
271.78
MOL File
14556-46-8.mol
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Bupranolol Property

Melting point:
71-74°C
Boiling point:
396.3±42.0 °C(Predicted)
Density 
1.098±0.06 g/cm3(Predicted)
storage temp. 
Hygroscopic, Refrigerator, Under Inert Atmosphere
solubility 
DMSO (Slightly), Methanol (Slightly)
form 
Solid
pka
13.82±0.20(Predicted)
color 
White to Off-White
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

TRC
Product number
B689650
Product name
Bupranolol
Packaging
500mg
Price
$215
Updated
2021/12/16
American Custom Chemicals Corporation
Product number
INB0000484
Product name
BUPRANOLOL
Purity
95.00%
Packaging
5MG
Price
$496.82
Updated
2021/12/16
Medical Isotopes, Inc.
Product number
44129
Product name
Bupranolol
Packaging
5G
Price
$2400
Updated
2021/12/16
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Bupranolol Chemical Properties,Usage,Production

Originator

Betadrenol,Pharma-Schwarz,W. Germany,1969

Uses

Bupranolol is an antagonist at the cardiostimulatory low-affinity state of b(1)-adrenoceptors and is known to treat hypertension and tachycardia.

Definition

ChEBI: Bupranolol is an aromatic ether.

Manufacturing Process

A mixture of 16.3 g of (2-chloro-5-methylphenyl)glycidic ether (from epichlorohydrin and 2-chloro-5-methylphenol) and 6.2 g of t-butylamine in 50 ml of ethanol is heated at reflux for 6 hours. The solvent is removed, the residue is washed with water and then extracted with benzene. The dried extract is evaporated to give 1-t-butylamino-3-(2-chloro-5-methylphenoxy)-2- propanol. Treatment of the free base in benzene solution with dry hydrogen chloride yields the hydrochloride salt.

Therapeutic Function

Antiarrhythmic

Bupranolol Preparation Products And Raw materials

Raw materials

Preparation Products

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Bupranolol Suppliers

J & K SCIENTIFIC LTD.
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010-82848833 400-666-7788
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86-10-82849933
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jkinfo@jkchemical.com
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China
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Chemsky(shanghai)International Co.,Ltd.
Tel
021-50135380
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shchemsky@sina.com
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China
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32321
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Hangzhou Sage Chemical Co., Ltd.
Tel
+86057186818502 13588463833
Fax
Pls mail us for more information!
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info@sagechem.com
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China
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AdooQ BioScience, LLC
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+1 (866) 930-6790
Fax
+1 (866) 333-9607
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info@adooq.com
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United States
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Chengdu Kamel Pharmaceutical Co., Ltd
Tel
028-67136579 15828051124
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sales@kamelpharm.com
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China
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Shanghai EFE Biological Technology Co., Ltd.
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021-65675885 18964387627
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Tianjin Kailiqi Biotechnology Co., Ltd.
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China
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Beijing OKA biological technology co., LTD
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010-010-010-62971590 18548936886
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Shenzhen Polymeri Biochemical Technology Co., Ltd.
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+86-400-002-6226 +86-13028896684;
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TargetMol Chemicals Inc.
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+1-781-999-5354 +1-00000000000
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marketing@targetmol.com
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United States
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14556-46-8, BupranololRelated Search:


  • (2S)-1-(tert-Butylamino)-3-(2-chloro-5-methylphenoxy)-2-propanol
  • (S)-1-(tert-Butylamino)-3-(2-chloro-5-methylphenoxy)-2-propanol
  • 1-(tert-Butylamino)-3-(2-chloro-5-methylphenoxy)-2-propanol
  • 1-(tert-Butylamino)-3-[(6-chloro-m-tolyl)oxy]-2-propanol
  • 1-[(2-Chloro-5-methylphenyl)oxy]-3-[(1,1-dimethylethyl)amino]propan-2-ol
  • Bupranolol
  • 2-Propanol, 1-(2-chloro-5-methylphenoxy)-3-[(1,1-dimethylethyl)amino]-
  • 2-Propanol, 1-(tert-butylamino)-3-[(6-chloro-m-tolyl)oxy]- (8CI)
  • Bupranol
  • Ophtorenin
  • B 1312; BRN 2272923; BUPRANOLOLUM; KL 255OPHTORENIN
  • BRN 2272923
  • Bupranololum
  • KL 255Ophtorenin
  • non-selective,competitive,Adrenergic Receptor,Bupranolol,Inhibitor,intrinsic,sympathomimetic,active,Beta Receptor,inhibit,orally
  • 14556-46-8