ChemicalBook > CAS DataBase List > 3-(3-methylbutanoyloxy)-4-trimethylammonio-butanoate

3-(3-methylbutanoyloxy)-4-trimethylammonio-butanoate

Product Name
3-(3-methylbutanoyloxy)-4-trimethylammonio-butanoate
CAS No.
31023-24-2
Chemical Name
3-(3-methylbutanoyloxy)-4-trimethylammonio-butanoate
Synonyms
isoverylcarnitine.;Isovalerylcarnitine;Isovaleroyl Carnitine;O-isovalerylcarnitine;ISOVALERYL-L-CARNITINE;3-methylbutyrylcarnitine;Isovaleryl-L-carnitine >=97.0% (TLC);3-(3-methylbutanoyloxy)-4-trimethylammonio-butanoate;(3R)-3-(3-Methylbutanoyloxy)-4-(trimethylazaniumyl)butanoate;(R)-3-((3-methylbutanoyl)oxy)-4-(trimethylammonio)butanoate(WXG00321)
CBNumber
CB11236041
Molecular Formula
C12H23NO4
Formula Weight
245.32
MOL File
31023-24-2.mol
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3-(3-methylbutanoyloxy)-4-trimethylammonio-butanoate Property

storage temp. 
2-8°C
solubility 
Soluble in DMSO
form 
Solid
color 
White to off-white
optical activity
[α]/D -23±2°, c = 1 in H2O
BRN 
5946880
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
51371
Product name
Isovaleryl-L-carnitine
Purity
≥94.0% (HPLC)
Packaging
10MG
Price
$90.4
Updated
2023/06/20
Sigma-Aldrich
Product number
51371
Product name
Isovaleryl-L-carnitine
Purity
≥94.0% (HPLC)
Packaging
50MG
Price
$357
Updated
2023/06/20
Sigma-Aldrich
Product number
91403
Product name
Isovaleryl-L-carnitine
Purity
analytical standard
Packaging
10MG
Price
$106
Updated
2022/05/15
Sigma-Aldrich
Product number
91403
Product name
Isovaleryl-L-carnitine
Purity
analytical standard
Packaging
50MG
Price
$371
Updated
2022/05/15
American Custom Chemicals Corporation
Product number
CHM0094535
Product name
3-(3-METHYLBUTANOYLOXY)-4-TRIMETHYLAMMONIO-BUTANOATE
Purity
95.00%
Packaging
10MG
Price
$709.46
Updated
2021/12/16
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3-(3-methylbutanoyloxy)-4-trimethylammonio-butanoate Chemical Properties,Usage,Production

Uses

Isovaleryl-L-carnitine may be used as an analytical reference standard for the quantification of the analyte in biological samples using chromatography-based techniques.

Definition

ChEBI: O-isovalerylcarnitine is a C5-acylcarnitine having isovaleryl as the acyl substituent. It has a role as a human metabolite. It is functionally related to an isovaleric acid.

General Description

Isovaleryl-L-carnitine belongs to the acylcarnitines class of compounds. Acyl-L-carnitines are mostly produced from L-carnitine, which plays an important role in fatty acid metabolic pathways. The functions and roles of acyl-L-carnitines in various tissues like brain, heart, and muscle continue to attract much interest, since a number of diseases caused by defects of mitochondrial transport are characterized by specific metabolic dysfunctions and depend on the physiological role of the affected carrier in intermediary metabolism.

Biochem/physiol Actions

Isovalerylcarnitine is the phenotypic abnormality in iso-valeric acidemia resulting from an accumulation of isovaleric acid, which is toxic to the central nervous system. Isovaleric acidemia is an autosomal recessive inborn error of leucine metabolism caused by a deficiency of the mitochondrial enzyme isovaleryl-CoA dehydrogenase resulting in the accumulation of derivatives of isovaleryl-CoA. It was the first organic acidemia recognized in humans and can cause significant morbidity and mortality. Early diagnosis and treatment with a protein restricted diet and supplementation with carnitine and glycine are effective in promoting normal development in severely affected individuals. An alternative pathway through glycine-N-acylase allows detoxification by producing isovaleryl-glycine, which is excreted. Thus, isovalerylcarnitine and isovalerylglycine are the hallmarks of this disorder in plasma and urine, respectively, and are elevated regardless of a patient′s metabolic condition.

3-(3-methylbutanoyloxy)-4-trimethylammonio-butanoate Preparation Products And Raw materials

Raw materials

Preparation Products

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3-(3-methylbutanoyloxy)-4-trimethylammonio-butanoate Suppliers

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31023-24-2, 3-(3-methylbutanoyloxy)-4-trimethylammonio-butanoateRelated Search:


  • 3-(3-methylbutanoyloxy)-4-trimethylammonio-butanoate
  • Isovalerylcarnitine
  • 3-methylbutyrylcarnitine
  • Isovaleroyl Carnitine
  • (3R)-3-(3-Methylbutanoyloxy)-4-(trimethylazaniumyl)butanoate
  • (R)-3-Carboxy-N,N,N-trimethyl-2-(3-methyl-1-oxobutoxy)-1-propanaminium inner salt
  • ISOVALERYL-L-CARNITINE
  • O-isovalerylcarnitine
  • (R)-3-((3-methylbutanoyl)oxy)-4-(trimethylammonio)butanoate(WXG00321)
  • Isovaleryl-L-carnitine >=97.0% (TLC)
  • isoverylcarnitine.
  • 31023-24-2