RIBOSTAMYCIN SULFATE SALT

Product Name: RIBOSTAMYCIN SULFATE SALT
CAS No.: 25546-65-0
Chemical Name: RIBOSTAMYCIN SULFATE SALT
Synonyms: sf733;ribomycin;NSC 138925;vistamycin;dekamyciniv;hetangmycin;ribostamycin;antibioticsf733;RIBOSTAMYCIN SULPHATE;RIBOSTAMYCIN DISULFATE
CBNumber: CB1165751
Molecular Formula: C17H34N4O10
Formula Weight: 454.47
MOL File: 25546-65-0.mol

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RIBOSTAMYCIN SULFATE SALT Property

Melting point:: 192-195°; mp 175-180° (dec)
alpha: D23 +42°
Boiling point:: 561.28°C (rough estimate)
Density: 1.1751 (rough estimate)
refractive index: 1.6700 (estimate)
storage temp.: 2-8°C
pka: 7.70(at 25℃)

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Safety

Hazard Codes: T
Risk Statements: 61-20/21/22
Safety Statements: 53-22-36/37/39-45
WGK Germany: 3
RTECS: WK2300000
Toxicity: mouse,LD50,intracrebral,66800ug/kg (66.8mg/kg),BEHAVIORAL: ALTERED SLEEP TIME (INCLUDING CHANGE IN RIGHTING REFLEX)BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLDLUNGS, THORAX, OR RESPIRATION: RESPIRATORY DEPRESSION,Kiso to Rinsho. Clinical Report. Vol. 4, Pg. 2489, 1970.

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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Usbiological

Product number: 257381
Product name: Ribostamycin sulphate
Packaging: 100mg
Price: $446
Updated: 2021/12/16

AvaChem

Product number: 2844
Product name: Ribostamycin
Packaging: 10g
Price: $850
Updated: 2021/12/16

AvaChem

Product number: 2844
Product name: Ribostamycin
Packaging: 25mg
Price: $45
Updated: 2021/12/16

AvaChem

Product number: 2844
Product name: Ribostamycin
Packaging: 100mg
Price: $75
Updated: 2021/12/16

AvaChem

Product number: 2844
Product name: Ribostamycin
Packaging: 1g
Price: $235
Updated: 2021/12/16

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RIBOSTAMYCIN SULFATE SALT Chemical Properties,Usage,Production

Description

Ribostamycin was found in the culture broth of Streptomyces ribosidificus by Meiji Seika Kaisha in 1970 in the course of screening aminoglycoside antibiotics. It is structurally related to neomycin but lacks the diaminoidose (glucose) moiety substituted on the ribose moiety. Ribostamycin is much less toxic than neomycin and shows strong activity against a variety of gram-positive and gram-negative bacteria, except Pseudomonas aeruginosa. It is used parenterally for therapy of urinary tract, respiratory tract, surgical, and other infections.

Definition

ChEBI: An amino cyclitol glycoside that is 4,6-diaminocyclohexane-1,2,3-triol having a 2,6-diamino-2,6-dideoxy-alpha-D-glucosyl residue attached at position 1 and a beta-D-ribosyl residue attache at position 2. It is an antibiotic produced by Streptomyces ribosidificus (formerly S. thermoflavus).

Mechanism of action

Ribostamycin (SF-733) is produced by Streptomyces ribosidificus. The free base is crystallized from methanol solution. The structure has been determined by chemical methods and total synthesis has been undertaken .

RIBOSTAMYCIN SULFATE SALT Preparation Products And Raw materials

Raw materials

Preparation Products

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RIBOSTAMYCIN SULFATE SALT Suppliers

China 13 Europe 2 Japan 1 Switzerland 1 United Kingdom 4 United States 7 Global 28

3B Pharmachem (Wuhan) International Co.,Ltd.

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25546-65-0, RIBOSTAMYCIN SULFATE SALTRelated Search:

RIBOSTAMYCIN SULFATE SALT N/,RIBOSTAMYCIN SULFATE SALT N/ NEOMYCIN C SULFATE RIBOSTAMYCIN SULFATE SALT BUTIROSIN DISULPHATE NEOMYCIN TRISULFATE SALT HYDRATE Neomycin NEOMYCIN B, SULPHATE, [3H]- Neomycin sulfate NEOMYCIN B TRISULFATE SESQUIHYDRATE PENICILLIN-STREPTOMYCIN-NEOMYCIN

RIBOSTAMYCIN DISULFATE

RIBOSTAMYCIN SULFATE SALT

RIBOSTAMYCIN SULPHATE

antibioticsf733

dekamyciniv

D-Streptamine, O-2,6-diamino-2,6-dideoxy-a-D-glucopyranosyl-(14)-O-[b-D-ribofuranosyl-(15)]-2-deoxy- (8CI, 9CI)

NSC 138925

Ribostamycin (base and/or unspecified salts)

4-O-(2,6-Diamino-2,6-dideoxy-α-D-glucopyranosyl)-5-O-(β-D-ribofuranosyl)-2-deoxy-D-streptamine

4-O-[2,6-Diamino-2,6-dideoxy-α-D-glucopyranosyl]-5-O-(β-D-ribofuranosyl)-2-deoxy-D-streptamine

d-ribofuranosyl-(1-5))-2-deoxy-

hetangmycin

ribostamycin

sf733

vistamycin

D-Streptamine, O-2,6-diamino-2,6-dideoxy-α-D-glucopyranosyl-(1→4)-O-[β-D-ribofuranosyl-(1→5)]-2-deoxy-

RIBOSTAMYCIN SULFATE SALT USP/EP/BP

ribomycin

25546-65-0

51797-35-6