ChemicalBook > CAS DataBase List > (2S,3R,E)-2-Amino-4-heptadecene-1,3-diol

(2S,3R,E)-2-Amino-4-heptadecene-1,3-diol

Product Name: (2S,3R,E)-2-Amino-4-heptadecene-1,3-diol
CAS No.: 6918-48-5
Chemical Name: (2S,3R,E)-2-Amino-4-heptadecene-1,3-diol
Synonyms: C17-Sphingosine;Sphingosine (d17:1);C17-D-erythro-Sphingosine;D-erythro-Sphingosine C-17;D-erythro-sphingosine (C17 base);D-erythro-Heptadecasphing-4-enine;(2S,3R,E)-2-Amino-4-heptadecene-1,3-diol;(2S,3R,4E)-2-Amino-4-heptadecene-1,3-diol;4-Heptadecene-1,3-diol, 2-amino-, (2S,3R,4E)-;D-ERYTHRO-SPHINGOSINE (C17 BASE);SPHINGOSINE (D17:1)
CBNumber: CB12399291
Molecular Formula: C17H35NO2
Formula Weight: 285.47
MOL File: 6918-48-5.mol

Less

(2S,3R,E)-2-Amino-4-heptadecene-1,3-diol Property

Boiling point:: 432.9±45.0 °C(Predicted)
Density: 0.944±0.06 g/cm3(Predicted)
storage temp.: -20°C
solubility: DMF: 10 mg/ml; DMSO: 2 mg/ml; Ethanol: Miscible
form: A crystalline solid
pka: 11.80±0.45(Predicted)
color: White to off-white

Less

Hazard and Precautionary Statements (GHS)

Less

N-Bromosuccinimide Price

Cayman Chemical

Product number: 10007902
Product name: Sphingosine (d17:1)
Purity: ≥98%
Packaging: 1mg
Price: $32
Updated: 2024/03/01

Cayman Chemical

Product number: 10007902
Product name: Sphingosine (d17:1)
Purity: ≥98%
Packaging: 5mg
Price: $143
Updated: 2024/03/01

Cayman Chemical

Product number: 10007902
Product name: Sphingosine (d17:1)
Purity: ≥98%
Packaging: 10mg
Price: $190
Updated: 2024/03/01

Cayman Chemical

Product number: 10007902
Product name: Sphingosine (d17:1)
Purity: ≥98%
Packaging: 25mg
Price: $396
Updated: 2024/03/01

TRC

Product number: S681005
Product name: D-erythro-Sphingosine-C17
Packaging: 10mg
Price: $160
Updated: 2021/12/16

Less

(2S,3R,E)-2-Amino-4-heptadecene-1,3-diol Chemical Properties,Usage,Production

Description

Sphingosine is an amino alcohol most commonly characterized by an 18-carbon unsaturated hydrocarbon chain sphingosine (d18:1) . However, the hydrocarbon chain length of sphingosine, and the related dihydrosphingosine, can vary from 12-26 carbons in mammalian tissues. Sphingosine (d17:1) is a naturally-occurring but uncommon form of sphingosine, accounting for approximately 13% of the sphingosine in human skin. It can be phosphorylated by sphingosine kinases to produce C-17 sphingosine-1-phosphate. More commonly, sphingosine C-17 is used as an internal standard in the analysis of sphingoid compounds by chromatographic or spectrometric methods.

Uses

Sphingosine (d17:1) has been used as a lipid standard in the analysis of sphingolipids by liquid chromatography-mass spectrometry (LC-MS) and tandem mass spectrometry.

Uses

D-erythro-Sphingosine-C17 is a substrate for sphingosine kinase.

Definition

ChEBI: C17 sphingosine is a sphingoid that is the C17 analogue of sphingosine. It is an aminodiol and a sphingoid. It is a conjugate base of a C17 sphingosine(1+).

General Description

Sphingosine (d17:1) or D-erythro-sphingosine is a 17-carbon sphingolipid, found in human skin. It has one carbon less than naturally occurring C18-sphingosine.

Biochem/physiol Actions

Sphingosine acts a precursor for sphingosine-1-phosphate (S1P). Sphingosine C-17 is used as an internal standard in the analysis of sphingolipids by spectrometric methods.

References

[1] MARY ELLEN STEWART Donald T D. Free Sphingosines of Human Skin Include 6-Hydroxysphingosine and Unusually Long-Chain Dihydrosphingosines[J]. Journal of Investigative Dermatology, 1995, 105 4: Pages 613-618. DOI: 10.1111/1523-1747.ep12323736
[2] JEONG HEE HONG . K6PC-5, a Direct Activator of Sphingosine Kinase 1, Promotes Epidermal Differentiation Through Intracellular Ca2+ Signaling[J]. Journal of Investigative Dermatology, 2008, 128 9: Pages 2166-2178. DOI: 10.1038/jid.2008.66
[3] CHANG-HWAN CHOI. Sphingosine 1-Phosphate and Sphingosine Kinase Activity during Chicken Embryonic Development[J]. Archives of Pharmacal Research, 2007, 30 4: 502-506. DOI: 10.1007/bf02980226
[4] STEVEN W PAUGH. A selective sphingosine kinase 1 inhibitor integrates multiple molecular therapeutic targets in human leukemia.[J]. Blood, 2008: 1382-1391. DOI: 10.1182/blood-2008-02-138958
[5] KAZUAKI TAKABE. Estradiol induces export of sphingosine 1-phosphate from breast cancer cells via ABCC1 and ABCG2.[J]. The Journal of Biological Chemistry, 2010: 10477-10486. DOI: 10.1074/jbc.m109.064162

(2S,3R,E)-2-Amino-4-heptadecene-1,3-diol Preparation Products And Raw materials

Raw materials

Preparation Products

Less

(2S,3R,E)-2-Amino-4-heptadecene-1,3-diol Suppliers

CHINA 54 India 1 United States 6 Global 61

Shanghai Aladdin Bio-Chem Technology Co.,LTD

Tel: 400-6206333 13167063860
Fax: 021-50323701
Email: anhua.mao@aladdin-e.com
Country: China
ProdList: 25003
Advantage: 65

Yichang Zhongyitai Trading Co., Ltd.

Tel: 0717-6449896 13886658719
Fax: 0717-6558598
Email: root@zhongyitai.com
Country: China
ProdList: 1978
Advantage: 58

Sigma-Aldrich

Tel: 021-61415566 800-8193336
Email: orderCN@merckgroup.com
Country: China
ProdList: 51395
Advantage: 80

Codow Chemical Co.,Ltd.

Tel: 18620099427
Fax: +86-20-62619665
Email: amy@howeipharm.com
Country: China
ProdList: 6687
Advantage: 55

Chengdu Huachun Technology Co., Ltd

Tel: 400-1166-196 15982826727
Fax: QQ：800101999
Email: cdhxsj@163.com
Country: China
ProdList: 14603
Advantage: 60

Shanghai Zhen Li Biological Technology Co., Ltd

Tel: 021-16621358918; 18516310516
Fax: 13045646768
Email: zhenlipharma888@163.com
Country: China
ProdList: 19035
Advantage: 58

Shanghai Jizhi Biochemical Technology Co. Ltd.

Tel: 4009004166/18616739031 18616739031
Email: 3007523370@qq.com
Country: China
ProdList: 52687
Advantage: 58

Shanghai Hongye Biotechnology Co. Ltd

Tel: 400-9205774
Email: sales@glpbio.cn
Country: China
ProdList: 6777
Advantage: 58

ChemeGen(Shanghai) Biotechnology Co.,Ltd.

Tel: 18818260767
Fax: QQ 3610331285
Email: sales@chemegen.com
Country: China
ProdList: 11218
Advantage: 58

Gill polypeptide biopharmaceutical (dalian) co., LTD

Tel: 021-61263455 13167021076
Email: amy@glschina.com
Country: China
ProdList: 9736
Advantage: 58

MedBioPharmaceutical Technology Inc

Tel: 021-69568360 18916172912
Email: order@med-bio.cn
Country: China
ProdList: 8140
Advantage: 58

Beijing PUXI Technology Co., Ltd

Tel: 400-8087372 13161114455
Email: puxi_sale@qq.com
Country: China
ProdList: 4990
Advantage: 58

TargetMol Chemicals Inc.

Tel: 4008200310
Email: marketing@tsbiochem.com
Country: China
ProdList: 24961
Advantage: 58

Shanghai Maclean Biochemical Technology Co., LTD

Tel: 021-021-50706066 15221275939
Email: shenlinxing@macklin.cn
Country: China
ProdList: 29784
Advantage: 58

Shanghai Haohong Scientific Co., Ltd.

Tel: 400-8210725 4008210725
Email: malulu@leyan.com
Country: China
ProdList: 40000
Advantage: 58

SHANGHAI ZZBIO CO., LTD.

Tel: 15102117276 19921389125
Email: tech@zzbioco.com
Country: China
ProdList: 12064
Advantage: 58

Beijing Putian Tongchuang Biotechnology Co., Ltd.

Tel: 18201332838
Email: 3032079623@qq.com
Country: China
ProdList: 6695
Advantage: 58

Sangon Biotech (Shanghai) Co.,Ltd.

Tel: 400-821-026
Email: Sales@sangon.com
Country: China
ProdList: 6710
Advantage: 58

Cayman Chemical Company

Tel: 800-364-9897
Email: sales@caymanchem.com
Country: China
ProdList: 6838
Advantage: 58

Enzo Biochem Inc

Tel: Enzo Biochem Inc. 13797054060
Email: Enzoname@qq.com
Country: China
ProdList: 6174
Advantage: 58

Merck KGaA

Tel: 21-20338288
Email: ordercn@merckgroup.com
Country: China
ProdList: 6394
Advantage: 58

Santa Cruz Biotechnology Inc

Tel: 021-60936350
Email: scbt@scbt.com
Country: China
ProdList: 6594
Advantage: 58

Guangzhou Qingyan Biotechnology Co., Ltd.

Tel: 19802084049
Country: CHINA
ProdList: 171
Advantage: 58

Shanghai Hongyu Biotechnology Co., Ltd.

Tel: 02158116080
Country: CHINA
ProdList: 147
Advantage: 58

Nanchang Bio-Tech Co., Ltd.

Tel: 13177864996
Country: CHINA
ProdList: 156
Advantage: 58

Guangzhou Lucheng Biotechnology Co., Ltd.

Tel: 16620452357
Country: CHINA
ProdList: 0
Advantage: 58

Guangzhou Qiansheng Biotechnology Co., Ltd.

Tel: 14748676110
Country: CHINA
ProdList: 112
Advantage: 58

Guangdong Zijinggang Technology Co., Ltd.

Tel: 13128698830
Country: CHINA
ProdList: 179
Advantage: 58

Guangzhou Keyuan Instrument Equipment Co., Ltd.

Tel: 13725272260
Country: CHINA
ProdList: 113
Advantage: 58

Neobioscience Co., Ltd.

Tel: --
Fax: --
Email: info@neobioscience.com
Country: CHINA
ProdList: 6207
Advantage: 58

Absin Bioscience Inc.

Tel: --
Fax: --
Email: chenjw@absin.cn
Country: CHINA
ProdList: 6208
Advantage: 58

Shanghai Weiwei Biological Technology Co., Ltd.

Tel: --
Fax: --
Email: sales@wheybio.com
Country: CHINA
ProdList: 4398
Advantage: 58

Morning Student Science and Technology (Guangzhou) Co., Ltd.

Tel: --
Fax: --
Email: chenxue_gz@163.com
Country: CHINA
ProdList: 6600
Advantage: 58

Shanghai Yaoyun Biological Technology Co., Ltd.

Tel: --
Fax: --
Email: 912529879@qq.com
Country: CHINA
ProdList: 6448
Advantage: 58

Shenzhen Xinbosheng Biological Technology Co., Ltd.

Tel: --
Fax: --
Email: service@neobioscience.com
Country: CHINA
ProdList: 6151
Advantage: 58

Shanghai Chaoyan Biotechnology Co., Ltd.

Tel: --
Fax: --
Email: 471161314@qq.com
Country: CHINA
ProdList: 6210
Advantage: 58

Resenbio

Tel: --
Fax: --
Email: sales@xarxbio.com
Country: China
ProdList: 1774
Advantage: 50

Shanghai Hao Biological Technology Co., Ltd.

Tel: --
Fax: --
Email: market@xlswkj.com
Country: CHINA
ProdList: 6793
Advantage: 58

Shanghai Hao Zhun Biological Technology Co., Ltd.

Tel: --
Fax: --
Email: info@zzsrm.com
Country: CHINA
ProdList: 6650
Advantage: 58

Rhenbo (Shanghai) Biochemical Technology Co., Ltd.

Tel: --
Fax: --
Country: CHINA
ProdList: 6333
Advantage: 58

Beijing Taize Jiaye Technology Development Co., Ltd.

Tel: --
Fax: --
Country: CHINA
ProdList: 6050
Advantage: 58

Shanghai Haoran Biotechnology Co., Ltd.

Tel: --
Fax: --
Email: 470003480@QQ.COM
Country: CHINA
ProdList: 6955
Advantage: 58

Shanghai Qincheng Biological Technology Co., Ltd.

Tel: --
Fax: --
Email: shqcsw01@163.com
Country: CHINA
ProdList: 6821
Advantage: 58

Beijing Luyuan Bird Biotechnology Co., Ltd.

Tel: --
Fax: --
Email: 15810802415@139.com
Country: CHINA
ProdList: 6750
Advantage: 58

Shanghai Jingke Chemical Technology Co., Ltd.

Tel: --
Fax: --
Email: jingkehuaxue@163.com
Country: CHINA
ProdList: 6141
Advantage: 58

Shanghai Zhenyu Biological Technology Co., Ltd.

Tel: --
Fax: --
Email: 2836767067@qq.com
Country: CHINA
ProdList: 6970
Advantage: 58

Shanghai Yuda Industrial Co., Ltd.

Tel: --
Fax: --
Email: lucy@runwelltac.com
Country: CHINA
ProdList: 6448
Advantage: 58

Shanghai Lianshuobao is Biotechnology Co., Ltd.

Tel: --
Fax: --
Email: lianshuobio@163.com
Country: CHINA
ProdList: 6984
Advantage: 58

Shanghai Benrui Biotechnology Co., Ltd.

Tel: --
Fax: --
Email: john.st@163.com
Country: CHINA
ProdList: 2160
Advantage: 58

Xiamen Huijia Biological Technology Co., Ltd.

Tel: --
Fax: --
Country: CHINA
ProdList: 6973
Advantage: 58

6918-48-5, (2S,3R,E)-2-Amino-4-heptadecene-1,3-diolRelated Search:

(2S,3R,E)-2-Amino-4-heptadecene-1,3-diol

C17-Sphingosine

D-erythro-Heptadecasphing-4-enine

D-erythro-Sphingosine C-17

D-erythro-sphingosine (C17 base)

D-ERYTHRO-SPHINGOSINE (C17 BASE);SPHINGOSINE (D17:1)

Sphingosine (d17:1)

C17-D-erythro-Sphingosine

4-Heptadecene-1,3-diol, 2-amino-, (2S,3R,4E)-

(2S,3R,4E)-2-Amino-4-heptadecene-1,3-diol

6918-48-5