Ranibizumab

ChemicalBook > CAS DataBase List > Ranibizumab

Product Name: Ranibizumab
CAS No.: 347396-82-1
Chemical Name: Ranibizumab
Synonyms: Lucentis;Ranibizumab;Unii-zl1R02vt79;Ranibizumab USP/EP/BP;Ranibizumab (anti-VEGF);Ranibizumab (anti-VEGFA);Research Grade Ranibizumab(DHD12601);Ranibizumab - 25mg/ml solution in PBS;Ranibizumab - Wet Macular Degeneration;RanibizumabQ: What is Ranibizumab Q: What is the CAS Number of Ranibizumab Q: What is the storage condition of Ranibizumab
CBNumber: CB12495883
Molecular Formula: C11H12N2O2
Formula Weight: 204.22518
MOL File: 347396-82-1.mol

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Ranibizumab Property

form: Liquid
color: Colorless to light yellow
CAS DataBase Reference: 347396-82-1

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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Biosynth Carbosynth

Product number: FR139132
Product name: Ranibizumab - 25mg/ml solution in PBS
Packaging: 1mg
Price: $125
Updated: 2021/12/16

Biosynth Carbosynth

Product number: FR139132
Product name: Ranibizumab - 25mg/ml solution in PBS
Packaging: 2mg
Price: $200
Updated: 2021/12/16

Biosynth Carbosynth

Product number: BR171775
Product name: Ranibizumab - 20mg/ml solution in PBS
Packaging: 1mg
Price: $250
Updated: 2021/12/16

Biosynth Carbosynth

Product number: BR171775
Product name: Ranibizumab - 20mg/ml solution in PBS
Packaging: 2mg
Price: $350
Updated: 2021/12/16

Biosynth Carbosynth

Product number: FR139132
Product name: Ranibizumab - 25mg/ml solution in PBS
Packaging: 5mg
Price: $400
Updated: 2021/12/16

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Ranibizumab Chemical Properties,Usage,Production

Description

Ranibizumab is a recombinant, humanized, IgG1 monoclonal antibody fragment (Fab) that neutralizes all active forms of vascular endothelial growth factor A (VEGF-A), and it is indicated for the treatment of neovascular age-related macular degeneration (AMD). It consists of a nonbinding human sequence and a high-affinity binding epitope (Fab fragment) derived from the mouse. The full-length RhuMab VEGF (bevacizumab) was launched previously by Genentech for the treatment of colorectal cancer. Both the antibody fragment and the full-length antibody bind to and inhibit all active forms of VEGF-A and are derived from the same mouse monoclonal antibody. However, ranibizumab has been genetically engineered through a process of selective mutation to increase its affinity for binding and inhibiting the growth factor.

Originator

Genentech (US)

Uses

antiangiogenic monoclonal antibody macular degeneration therapy

Uses

Ranibizumab, a humanized antigen binding portion of a murine anti- VEGF monoclonal antibody with a mature high affinity for all VEGF isoforms, has been approved as an intravitreal treatment for neovascular AMD and is the first such treatment to improve visual acuity (VA) in neovascular AMD.
CRUISE is multicenter, randomized, double-masked, sham injectioncontrolled Phase III study of 392 participants designed to assess the efficiency and safety profile of ranimizumab for macular edema associated to CRVO. The month 6 result showed that 46.2% (61/132) of patients received 0.3 mg of ranimizumab and 47.7% (62/130) received 0.5 mg of ranimizumab had their vision improved by 15 letters or more compared to 16.9% (22/130) of patients receiving sham injections and mean gain was observed beginning at day seven with an 8.8 and 9.3 letter gain in the 0.3 mg and 0.5 mg study arms of ranimizumab, respectively, compared with 1.1 letters in the sham injection arm.

brand name

Lucentis

Ranibizumab Preparation Products And Raw materials

Raw materials

Preparation Products

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Ranibizumab Suppliers

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View Lastest Price from Ranibizumab manufacturers

Shaanxi TNJONE Pharmaceutical Co., Ltd

Product: Ranibizumab 347396-82-1
Price: US $0.00/kg
Min. Order: 1kg
Purity: 99%
Supply Ability: 10000kg
Release date: 2024-05-24

Hangzhou Huarong Pharm Co., Ltd.

Product: Ranibizumab 347396-82-1
Price: US $0.00-0.00/mg
Min. Order: 5mg
Purity: 99%
Supply Ability: 100KG
Release date: 2021-09-15

Wuhan Monad Medicine Tech Co.,LTD

Product: Ranibizumab 347396-82-1
Price: US $10.00/KG
Min. Order: 1KG
Purity: 99.99%
Supply Ability: 20 tons/month
Release date: 2021-04-19

347396-82-1, RanibizumabRelated Search:

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Lucentis

Ranibizumab

Unii-zl1R02vt79

Ranibizumab - 25mg/ml solution in PBS

Ranibizumab USP/EP/BP

RanibizumabQ: What is Ranibizumab Q: What is the CAS Number of Ranibizumab Q: What is the storage condition of Ranibizumab

Research Grade Ranibizumab(DHD12601)

Ranibizumab (anti-VEGF)

Ranibizumab (anti-VEGFA)

Ranibizumab - Wet Macular Degeneration

347396-82-1