ChemicalBook > CAS DataBase List > 2-AMino-4-chloro-pyriMidine-5-carbonitrile

2-AMino-4-chloro-pyriMidine-5-carbonitrile

Product Name
2-AMino-4-chloro-pyriMidine-5-carbonitrile
CAS No.
1393179-35-5
Chemical Name
2-AMino-4-chloro-pyriMidine-5-carbonitrile
Synonyms
EOS-60723;2-Amino-4-chloro-5-cyanopyrimidine;2-Amino-4-chloro-5-pyrimidinecarbonitrile;2-AMino-4-chloro-pyriMidine-5-carbonitrile;5-Pyrimidinecarbonitrile, 2-amino-4-chloro-
CBNumber
CB12653799
Molecular Formula
C5H3ClN4
Formula Weight
154.56
MOL File
1393179-35-5.mol
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2-AMino-4-chloro-pyriMidine-5-carbonitrile Property

storage temp. 
-20°C, sealed storage, away from moisture and light
Appearance
White to off-white Solid
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H332Harmful if inhaled

H335May cause respiratory irritation

Precautionary statements

P280Wear protective gloves/protective clothing/eye protection/face protection.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P310Immediately call a POISON CENTER or doctor/physician.

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N-Bromosuccinimide Price

AK Scientific
Product number
2433AQ
Product name
2-Amino-4-chloro-pyrimidine-5-carbonitrile
Packaging
500mg
Price
$424.4
Updated
2021/12/16
Crysdot
Product number
CD11266452
Product name
2-Amino-4-chloropyrimidine-5-carbonitrile
Purity
95+%
Packaging
1g
Price
$380
Updated
2021/12/16
Chemenu
Product number
CM122331
Product name
2-amino-4-chloropyrimidine-5-carbonitrile
Purity
95%
Packaging
1g
Price
$664
Updated
2021/12/16
Crysdot
Product number
CD11266452
Product name
2-Amino-4-chloropyrimidine-5-carbonitrile
Purity
95+%
Packaging
5g
Price
$1140
Updated
2021/12/16
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2-AMino-4-chloro-pyriMidine-5-carbonitrile Chemical Properties,Usage,Production

Synthesis

3177-24-0

1393179-35-5

General procedure for the synthesis of 2-amino-4-chloro-5-cyanopyrimidine from 2,4-dichloropyrimidine-5-carbonitrile: To a solution of 2,4-dichloropyrimidine-5-carbonitrile (600 mg, 3.45 mmol) in dioxane (20 mL) was added a dioxane solution of 0.5 M ammonia (20 mL, 10 mmol). The reaction mixture was stirred at room temperature for 4 hours. Upon completion of the reaction, two isomers were isolated by column chromatography using a hexane/ethyl acetate solvent mixture (ethyl acetate ratio increased from 0% to 45%). Among them, 2-amino-4-chloro-5-cyanopyrimidine (304 mg, 56% yield) was isolated as the less polar isomer. Low resolution mass spectrometry (LRMS) showed m/z of 153 (M-1).

References

[1] Patent: WO2012/146666, 2012, A1. Location in patent: Page/Page column 166

2-AMino-4-chloro-pyriMidine-5-carbonitrile Preparation Products And Raw materials

Raw materials

Preparation Products

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2-AMino-4-chloro-pyriMidine-5-carbonitrile Suppliers

China 34 United States 1 Global 35
Matrix Scientific
Tel
--
Fax
--
Email
sales@matrixscientific.com
Country
United States
ProdList
6632
Advantage
80

1393179-35-5, 2-AMino-4-chloro-pyriMidine-5-carbonitrileRelated Search:


  • 2-AMino-4-chloro-pyriMidine-5-carbonitrile
  • 2-Amino-4-chloro-5-cyanopyrimidine
  • EOS-60723
  • 5-Pyrimidinecarbonitrile, 2-amino-4-chloro-
  • 2-Amino-4-chloro-5-pyrimidinecarbonitrile
  • 1393179-35-5