ChemicalBook > CAS DataBase List > FL118

FL118

Product Name
FL118
CAS No.
151636-76-9
Chemical Name
FL118
Synonyms
FL118;CS-1718;10,11-(methylenedioxy)-(20R)-camptothecin;(R)-7-Ethyl-7-hydroxy-7H-[1,3]dioxolo[4,5-g]pyrano[3',4':6,7]indolizino[1,2-b]quinoline-8,11(10H,13H)-dione;10H-1,3-Dioxolo[4,5-g]pyrano[3',4':6,7]indolizino[1,2-b]quinoline-8,11(7H,13H)-dione, 7-ethyl-7-hydroxy-, (7R)-;(5R)-5-ethyl-5-hydroxy-7,18,20-trioxa-11,24-diazahexacyclo[11.11.0.02,11.0?,?.01?,23.01?,21]tetracosa-1(13),2,4(9),14,16,21,23-heptaene-6,10-dione
CBNumber
CB12716227
Molecular Formula
C21H16N2O6
Formula Weight
392.36
MOL File
151636-76-9.mol
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FL118 Property

Boiling point:
812.1±65.0 °C(Predicted)
Density 
1?+-.0.1 g/cm3(Predicted)
storage temp. 
Store at -20°C
solubility 
DMSO : 2.7 mg/mL (6.88 mM; ultrasonic and warming and heat to 60°C)
form 
Solid
pka
11.18±0.20(Predicted)
color 
Off-white to yellow
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

TRC
Product number
F401290
Product name
(R)-FL-118
Packaging
5mg
Price
$2475
Updated
2021/12/16
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FL118 Chemical Properties,Usage,Production

Uses

(R)-FL-118 is a derivative of Camptothecin (C175150), which is antitumor alkaloid that binds to the DNA-topoisomerase I complex, inhibiting the reassociation of DNA after cleavage by topoisomerase I, trapping the enzyme in a covalent linkage with DNA.

FL118 Preparation Products And Raw materials

Raw materials

Preparation Products

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FL118 Suppliers

Sichuan Wei Keqi Biological Technology Co., Ltd.
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151636-76-9, FL118Related Search:


  • FL118
  • CS-1718
  • 10,11-(methylenedioxy)-(20R)-camptothecin
  • 10H-1,3-Dioxolo[4,5-g]pyrano[3',4':6,7]indolizino[1,2-b]quinoline-8,11(7H,13H)-dione, 7-ethyl-7-hydroxy-, (7R)-
  • (R)-7-Ethyl-7-hydroxy-7H-[1,3]dioxolo[4,5-g]pyrano[3',4':6,7]indolizino[1,2-b]quinoline-8,11(10H,13H)-dione
  • (5R)-5-ethyl-5-hydroxy-7,18,20-trioxa-11,24-diazahexacyclo[11.11.0.02,11.0?,?.01?,23.01?,21]tetracosa-1(13),2,4(9),14,16,21,23-heptaene-6,10-dione
  • 151636-76-9