FL118

Product Name: FL118
CAS No.: 151636-76-9
Chemical Name: FL118
Synonyms: FL118;CS-1718;10,11-(methylenedioxy)-(20R)-camptothecin;(R)-7-Ethyl-7-hydroxy-7H-[1,3]dioxolo[4,5-g]pyrano[3',4':6,7]indolizino[1,2-b]quinoline-8,11(10H,13H)-dione;10H-1,3-Dioxolo[4,5-g]pyrano[3',4':6,7]indolizino[1,2-b]quinoline-8,11(7H,13H)-dione, 7-ethyl-7-hydroxy-, (7R)-;(5R)-5-ethyl-5-hydroxy-7,18,20-trioxa-11,24-diazahexacyclo[11.11.0.02,11.0?,?.01?,23.01?,21]tetracosa-1(13),2,4(9),14,16,21,23-heptaene-6,10-dione
CBNumber: CB12716227
Molecular Formula: C21H16N2O6
Formula Weight: 392.36
MOL File: 151636-76-9.mol

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FL118 Property

Boiling point:: 812.1±65.0 °C(Predicted)
Density: 1?+-.0.1 g/cm3(Predicted)
storage temp.: Store at -20°C
solubility: DMSO : 2.7 mg/mL (6.88 mM; ultrasonic and warming and heat to 60°C)
form: Solid
pka: 11.18±0.20(Predicted)
color: Off-white to yellow

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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

TRC

Product number: F401290
Product name: (R)-FL-118
Packaging: 5mg
Price: $2475
Updated: 2021/12/16

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FL118 Chemical Properties,Usage,Production

Uses

(R)-FL-118 is a derivative of Camptothecin (C175150), which is antitumor alkaloid that binds to the DNA-topoisomerase I complex, inhibiting the reassociation of DNA after cleavage by topoisomerase I, trapping the enzyme in a covalent linkage with DNA.

FL118 Preparation Products And Raw materials

Raw materials

Preparation Products

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FL118 Suppliers

China 25 India 1 United States 3 Global 29

151636-76-9, FL118Related Search:

FL118

CS-1718

10,11-(methylenedioxy)-(20R)-camptothecin

10H-1,3-Dioxolo[4,5-g]pyrano[3',4':6,7]indolizino[1,2-b]quinoline-8,11(7H,13H)-dione, 7-ethyl-7-hydroxy-, (7R)-

(R)-7-Ethyl-7-hydroxy-7H-[1,3]dioxolo[4,5-g]pyrano[3',4':6,7]indolizino[1,2-b]quinoline-8,11(10H,13H)-dione

(5R)-5-ethyl-5-hydroxy-7,18,20-trioxa-11,24-diazahexacyclo[11.11.0.02,11.0?,?.01?,23.01?,21]tetracosa-1(13),2,4(9),14,16,21,23-heptaene-6,10-dione

151636-76-9