1-Methyl-1-[4-(4-trifluoromethoxy-phenyl)-1H-imidazol-2-yl]-ethylamine

Product Name: 1-Methyl-1-[4-(4-trifluoromethoxy-phenyl)-1H-imidazol-2-yl]-ethylamine
CAS No.: 1480833-70-2
Chemical Name: 1-Methyl-1-[4-(4-trifluoromethoxy-phenyl)-1H-imidazol-2-yl]-ethylamine
Synonyms: PF-04885614;PF-04885614, 10 mM in DMSO;2-(4-(4-(Trifluoromethoxy)phenyl)-1H-imidazol-2-yl)propan-2-amine;1-Methyl-1-[4-(4-trifluoromethoxy-phenyl)-1H-imidazol-2-yl]-ethylamine;1H-Imidazole-2-methanamine, α,α-dimethyl-5-[4-(trifluoromethoxy)phenyl]-;PF04885614,neurodevelopmental,neurological,PF-04885614,ion,Inhibitor,inhibit,Na+ channels,Sodium Channel,channel,PF 04885614,diseases,Na channels
CBNumber: CB12891553
Molecular Formula: C13H14F3N3O
Formula Weight: 285.2649696
MOL File: 1480833-70-2.mol

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1-Methyl-1-[4-(4-trifluoromethoxy-phenyl)-1H-imidazol-2-yl]-ethylamine Property

Boiling point:: 414.6±45.0 °C(Predicted)
Density: 1.293±0.06 g/cm3(Predicted)
storage temp.: room temp
solubility: <28.53mg/ml in DMSO; <28.53mg/ml in ethanol
form: Solid
pka: 13.83±0.10(Predicted)
color: Off-white to light yellow

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Safety

Hazard Codes: Xi
Risk Statements: 36/37/38
Safety Statements: 26

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P332+P313IF SKIN irritation occurs: Get medical advice/attention.

P337+P313IF eye irritation persists: Get medical advice/attention.

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N-Bromosuccinimide Price

Tocris

Product number: 4916
Product name: PF04885614
Purity: ≥98%(HPLC)
Packaging: 10
Price: $191
Updated: 2021/12/16

TRC

Product number: P294118
Product name: PF04885614
Packaging: 5mg
Price: $330
Updated: 2021/12/16

ApexBio Technology

Product number: B5765
Product name: PF04885614
Packaging: 10mg
Price: $290
Updated: 2021/12/16

ApexBio Technology

Product number: B5765
Product name: PF04885614
Packaging: 50mg
Price: $1221
Updated: 2021/12/16

Crysdot

Product number: CD11252092
Product name: 2-(4-(4-(Trifluoromethoxy)phenyl)-1H-imidazol-2-yl)propan-2-amine
Purity: 97%
Packaging: 5g
Price: $2213
Updated: 2021/12/16

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1-Methyl-1-[4-(4-trifluoromethoxy-phenyl)-1H-imidazol-2-yl]-ethylamine Chemical Properties,Usage,Production

Uses

PF-04885614 is a potent NaV1.8 inhibitor, extracted from patent US2018328915. PF-04885614 has potential for neurological and neurodevelopmental diseases treatment[1].

Biological Activity

PF-04885614 is a potent and selective Nav1.8 inhibitor.

storage

Store at +4°C

References

[1] Brady MAHER, et al. Treatment of Neurological and Neurodevelopmental Diseases and Disorders Associated with Aberrant Ion Channel Expression and Activity. US20180328915A1.

1-Methyl-1-[4-(4-trifluoromethoxy-phenyl)-1H-imidazol-2-yl]-ethylamine Preparation Products And Raw materials

Raw materials

Preparation Products

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1-Methyl-1-[4-(4-trifluoromethoxy-phenyl)-1H-imidazol-2-yl]-ethylamine Suppliers

China 23 United States 6 Global 29

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1480833-70-2, 1-Methyl-1-[4-(4-trifluoromethoxy-phenyl)-1H-imidazol-2-yl]-ethylamineRelated Search:

1-Methyl-1-[4-(4-trifluoromethoxy-phenyl)-1H-imidazol-2-yl]-ethylamine

PF-04885614

2-(4-(4-(Trifluoromethoxy)phenyl)-1H-imidazol-2-yl)propan-2-amine

PF04885614,neurodevelopmental,neurological,PF-04885614,ion,Inhibitor,inhibit,Na+ channels,Sodium Channel,channel,PF 04885614,diseases,Na channels

1H-Imidazole-2-methanamine, α,α-dimethyl-5-[4-(trifluoromethoxy)phenyl]-

PF-04885614, 10 mM in DMSO

1480833-70-2