1-Methyl-1-[4-(4-trifluoromethoxy-phenyl)-1H-imidazol-2-yl]-ethylamine
- Product Name
- 1-Methyl-1-[4-(4-trifluoromethoxy-phenyl)-1H-imidazol-2-yl]-ethylamine
- CAS No.
- 1480833-70-2
- Chemical Name
- 1-Methyl-1-[4-(4-trifluoromethoxy-phenyl)-1H-imidazol-2-yl]-ethylamine
- Synonyms
- PF-04885614;PF-04885614, 10 mM in DMSO;2-(4-(4-(Trifluoromethoxy)phenyl)-1H-imidazol-2-yl)propan-2-amine;1-Methyl-1-[4-(4-trifluoromethoxy-phenyl)-1H-imidazol-2-yl]-ethylamine;1H-Imidazole-2-methanamine, α,α-dimethyl-5-[4-(trifluoromethoxy)phenyl]-;PF04885614,neurodevelopmental,neurological,PF-04885614,ion,Inhibitor,inhibit,Na+ channels,Sodium Channel,channel,PF 04885614,diseases,Na channels
- CBNumber
- CB12891553
- Molecular Formula
- C13H14F3N3O
- Formula Weight
- 285.2649696
- MOL File
- 1480833-70-2.mol
1-Methyl-1-[4-(4-trifluoromethoxy-phenyl)-1H-imidazol-2-yl]-ethylamine Property
- Boiling point:
- 414.6±45.0 °C(Predicted)
- Density
- 1.293±0.06 g/cm3(Predicted)
- storage temp.
- room temp
- solubility
- <28.53mg/ml in DMSO; <28.53mg/ml in ethanol
- form
- Solid
- pka
- 13.83±0.10(Predicted)
- color
- Off-white to light yellow
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H315Causes skin irritation
H319Causes serious eye irritation
- Precautionary statements
-
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P332+P313IF SKIN irritation occurs: Get medical advice/attention.
P337+P313IF eye irritation persists: Get medical advice/attention.
N-Bromosuccinimide Price
- Product number
- 4916
- Product name
- PF04885614
- Purity
- ≥98%(HPLC)
- Packaging
- 10
- Price
- $191
- Updated
- 2021/12/16
- Product number
- P294118
- Product name
- PF04885614
- Packaging
- 5mg
- Price
- $330
- Updated
- 2021/12/16
- Product number
- B5765
- Product name
- PF04885614
- Packaging
- 10mg
- Price
- $290
- Updated
- 2021/12/16
- Product number
- B5765
- Product name
- PF04885614
- Packaging
- 50mg
- Price
- $1221
- Updated
- 2021/12/16
- Product number
- CD11252092
- Product name
- 2-(4-(4-(Trifluoromethoxy)phenyl)-1H-imidazol-2-yl)propan-2-amine
- Purity
- 97%
- Packaging
- 1g
- Price
- $837
- Updated
- 2021/12/16
1-Methyl-1-[4-(4-trifluoromethoxy-phenyl)-1H-imidazol-2-yl]-ethylamine Chemical Properties,Usage,Production
Uses
PF-04885614 is a potent NaV1.8 inhibitor, extracted from patent US2018328915. PF-04885614 has potential for neurological and neurodevelopmental diseases treatment[1].
Biological Activity
PF-04885614 is a potent and selective Nav1.8 inhibitor.
storage
Store at +4°C
References
[1] Brady MAHER, et al. Treatment of Neurological and Neurodevelopmental Diseases and Disorders Associated with Aberrant Ion Channel Expression and Activity. US20180328915A1.
1-Methyl-1-[4-(4-trifluoromethoxy-phenyl)-1H-imidazol-2-yl]-ethylamine Preparation Products And Raw materials
Raw materials
Preparation Products
1-Methyl-1-[4-(4-trifluoromethoxy-phenyl)-1H-imidazol-2-yl]-ethylamine Suppliers
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