Adomeglivant

Product Name: Adomeglivant
CAS No.: 1488363-78-5
Chemical Name: Adomeglivant
Synonyms: LY-2409021;Adomeglivant;Adomeglivant ( LY2409021);Adomeglivant, 10 mM in DMSO;β-Alanine, N-[4-[(1S)-1-[[4'-(1,1-dimethylethyl)-2,6-dimethyl[1,1'-biphenyl]-4-yl]oxy]-4,4,4-trifluorobutyl]benzoyl]-
CBNumber: CB13134114
Molecular Formula: C32H36F3NO4
Formula Weight: 555.64
MOL File: 1488363-78-5.mol

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Adomeglivant Property

Boiling point:: 656.7±55.0 °C(Predicted)
Density: 1.173±0.06 g/cm3(Predicted)
storage temp.: Store at -20°C
solubility: DMSO:100.0(Max Conc. mg/mL);179.97(Max Conc. mM)
Ethanol:100.0(Max Conc. mg/mL);179.97(Max Conc. mM)
form: A solid
pka: 4.28±0.10(Predicted)
color: White to off-white

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Danger

Hazard statements

H315Causes skin irritation

H317May cause an allergic skin reaction

H318Causes serious eye damage

H334May cause allergy or asthma symptoms or breathing difficulties if inhaled

H335May cause respiratory irritation

H341Suspected of causing genetic defects

H361Suspected of damaging fertility or the unborn child

H370Causes damage to organs

H413May cause long lasting harmful effects to aquatic life

Precautionary statements

P201Obtain special instructions before use.

P202Do not handle until all safety precautions have been read and understood.

P260Do not breathe dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P272Contaminated work clothing should not be allowed out of the workplace.

P273Avoid release to the environment.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P284Wear respiratory protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P304+P341IF INHALED: If breathing is difficult, remove victim to fresh air and keep at rest in a position comfortable for breathing.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P308+P313IF exposed or concerned: Get medical advice/attention.

P310Immediately call a POISON CENTER or doctor/physician.

P321Specific treatment (see … on this label).

P333+P313IF SKIN irritation or rash occurs: Get medical advice/attention.

P342+P311IF experiencing respiratory symptoms: call a POISON CENTER or doctor/physician.

P363Wash contaminated clothing before reuse.

P405Store locked up.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

Cayman Chemical

Product number: 29668
Product name: Adomeglivant
Packaging: 5mg
Price: $116
Updated: 2024/03/01

Cayman Chemical

Product number: 29668
Product name: Adomeglivant
Packaging: 25mg
Price: $456
Updated: 2024/03/01

Cayman Chemical

Product number: 29668
Product name: Adomeglivant
Packaging: 1mg
Price: $32
Updated: 2024/03/01

Cayman Chemical

Product number: 29668
Product name: Adomeglivant
Packaging: 10mg
Price: $214
Updated: 2024/03/01

ChemScene

Product number: CS-5729
Product name: Adomeglivant
Purity: 99.84%
Packaging: 5mg
Price: $120
Updated: 2021/12/16

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Adomeglivant Chemical Properties,Usage,Production

Uses

Adomeglivant is a glucagon receptor antagonist used in the combined treatment of type 2 diabetes.

in vivo

Adomeglivant (5 mg/kg; i.p.) completely abolishes the hyperglycaemic action of CNO (clozapine-N-oxide) in Avp^ires-Cre+ mice. (CNO is a specific, pharmacologically inert agonist for hM3Dq-induced membrane depolarisation and increased the firing rate in hM3Dq-expressing arginine-vasopressin (AVP) neurons.)^[3]

Animal Model:	Avp^ires-Cre+ mice^[3]
Dosage:	5 mg/kg
Administration:	Intraperitoneal injection, 30 minutes prior to CNO
Result:	Completely abolished the hyperglycaemic action of CNO.

Adomeglivant Preparation Products And Raw materials

Raw materials

Preparation Products

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Adomeglivant Suppliers

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1488363-78-5, AdomeglivantRelated Search:

Adomeglivant

LY-2409021

β-Alanine, N-[4-[(1S)-1-[[4'-(1,1-dimethylethyl)-2,6-dimethyl[1,1'-biphenyl]-4-yl]oxy]-4,4,4-trifluorobutyl]benzoyl]-

Adomeglivant ( LY2409021)

Adomeglivant, 10 mM in DMSO

1488363-78-5

C32H36F3NO4