ChemicalBook > CAS DataBase List > 2H-Purin-2-one,1,3,6,9-tetrahydro-1,3-dimethyl-8-[[2-(4-morpholinyl)ethyl]thio]-6-thioxo-
2H-Purin-2-one,1,3,6,9-tetrahydro-1,3-dimethyl-8-[[2-(4-morpholinyl)ethyl]thio]-6-thioxo-
- Product Name
- 2H-Purin-2-one,1,3,6,9-tetrahydro-1,3-dimethyl-8-[[2-(4-morpholinyl)ethyl]thio]-6-thioxo-
- CAS No.
- 6505-99-3
- Chemical Name
- 2H-Purin-2-one,1,3,6,9-tetrahydro-1,3-dimethyl-8-[[2-(4-morpholinyl)ethyl]thio]-6-thioxo-
- Synonyms
- JA2131;JA2131(NSC98003);1,3-dimethyl-8-(2-morpholin-4-ylethylsulfanyl)-6-sulfanylidene-7H-purin-2-one;2H-Purin-2-one,1,3,6,9-tetrahydro-1,3-dimethyl-8-[[2-(4-morpholinyl)ethyl]thio]-6-thioxo-
- CBNumber
- CB13230100
- Molecular Formula
- C13H19N5O2S2
- Formula Weight
- 341.45226
- MOL File
- 6505-99-3.mol
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2H-Purin-2-one,1,3,6,9-tetrahydro-1,3-dimethyl-8-[[2-(4-morpholinyl)ethyl]thio]-6-thioxo- Property
- storage temp.
- 2-8°C
- solubility
- DMSO: 2mg/mL, clear
- form
- Solid
- color
- White to off-white
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N-Bromosuccinimide Price
DC Chemicals
- Product number
- DC26170
- Product name
- JA2131
- Packaging
- 5mg
- Price
- $750
- Updated
- 2021/12/16
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2H-Purin-2-one,1,3,6,9-tetrahydro-1,3-dimethyl-8-[[2-(4-morpholinyl)ethyl]thio]-6-thioxo- Chemical Properties,Usage,Production
Biological Activity
JA2131 is a cell penetrant, potent and selective poly(ADP-ribose) glycohydrolase (PARG) inhibitor th at selectively kills cancer cells. JA2131 induces PARP1 hyper-PARylation and sensitizes cancer cells to radiation-induced DNA damage. JA2131 induces replication fork defects.
2H-Purin-2-one,1,3,6,9-tetrahydro-1,3-dimethyl-8-[[2-(4-morpholinyl)ethyl]thio]-6-thioxo- Preparation Products And Raw materials
Raw materials
Preparation Products
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2H-Purin-2-one,1,3,6,9-tetrahydro-1,3-dimethyl-8-[[2-(4-morpholinyl)ethyl]thio]-6-thioxo- Suppliers
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- +8613564774135
- zijue.cai@tsbiochem.com
- Country
- United States
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- 19881
- Advantage
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- tp@aladdinsci.com
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- United States
- ProdList
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