H2N-PEG3-CH2COOtBu

Product Name: H2N-PEG3-CH2COOtBu
CAS No.: 189808-70-6
Chemical Name: H2N-PEG3-CH2COOtBu
Synonyms: NH2-PEG3-C1-Boc;H2N-PEG3-CH2COOtBu;NH2-PEG3-CH2COOtBu;Amino-PEG3-CH2COOtBu;Amino-peg3-butyl ester;Amino-PEG3-CH2COOH t-Bu Ester;Amino-PEG3-CH2CO2-t-butyl ester;tert-Butyl 2-(2-(2-(2-aminoethoxy)ethoxy)ethoxy)acetate;Acetic acid, 2-[2-[2-(2-aminoethoxy)ethoxy]ethoxy]-, 1,1-dimethylethyl ester;H2N-PEG3-CH2COOtBu/Acetic acid, 2-[2-[2-(2-aminoethoxy)ethoxy]ethoxy]-, 1,1-dimethylethyl ester
CBNumber: CB13340571
Molecular Formula: C12H25NO5
Formula Weight: 263.33
MOL File: 189808-70-6.mol

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H2N-PEG3-CH2COOtBu Property

Boiling point:: 343.4±27.0 °C(Predicted)
Density: 1.041±0.06 g/cm3(Predicted)
storage temp.: under inert gas (nitrogen or Argon) at 2–8 °C
solubility: Soluble in Water, DMSO, DCM, DMF
pka: 8.74±0.10(Predicted)
form: Liquid
color: Colorless to light yellow
InChI: InChI=1S/C12H25NO5/c1-12(2,3)18-11(14)10-17-9-8-16-7-6-15-5-4-13/h4-10,13H2,1-3H3
InChIKey: OTTHWLFOQWLZKB-UHFFFAOYSA-N
SMILES: C(OC(C)(C)C)(=O)COCCOCCOCCN

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P312Call a POISON CENTER or doctor/physician if you feel unwell.

P321Specific treatment (see … on this label).

P332+P313IF SKIN irritation occurs: Get medical advice/attention.

P337+P313IF eye irritation persists: Get medical advice/attention.

P362Take off contaminated clothing and wash before reuse.

P403+P233Store in a well-ventilated place. Keep container tightly closed.

P405Store locked up.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

BroadPharm

Product number: BP-23620
Product name: Amino-PEG3-CH2CO2-t-butylester
Purity: 98%
Packaging: 1g
Price: $215
Updated: 2021/12/16

AK Scientific

Product number: AMTGC504
Product name: tert-Butyl 2-(2-(2-(2-aminoethoxy)ethoxy)ethoxy)acetate
Purity: 97%
Packaging: 1g
Price: $215
Updated: 2021/12/16

Activate Scientific

Product number: AS104023
Product name: H2N-PEG3-CH2COOtBu
Purity: 95+%
Packaging: 1g
Price: $342
Updated: 2021/12/16

Activate Scientific

Product number: AS104023
Product name: H2N-PEG3-CH2COOtBu
Purity: 95+%
Packaging: 5G
Price: $897
Updated: 2021/12/16

purepeg

Product number: 4328203
Product name: H2N-PEG3-CH2COOtBu
Purity: min.97%
Packaging: 5G
Price: $650
Updated: 2021/12/16

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H2N-PEG3-CH2COOtBu Chemical Properties,Usage,Production

Description

Amino-PEG3-CH2CO2-t-butyl ester is a PEG molecule containing an amino group with a t-butyl protected carboxyl group. The hydrophilic PEG spacer increases solubility in aqueous media. The amino group is reactive with carboxylic acids, activated NHS esters, carbonyls (ketone, aldehyde) etc. The t-butyl protected carboxyl group (t-Boc) can be deprotected under acidic conditions.

Uses

NH2-PEG3-C1-Boc (PROTAC Linker 5) is a PEG-based PROTAC linker can be used in the synthesis of PROTACs[1].

IC 50

PEGs; Alkyl/ether

References

[1] An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562. DOI:10.1016/j.ebiom.2018.09.005

H2N-PEG3-CH2COOtBu Preparation Products And Raw materials

Raw materials

Preparation Products

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H2N-PEG3-CH2COOtBu Suppliers

Canada 1 China 69 United States 5 Global 75

R&D Scientific Inc.

Tel: +1-2266000236
Email: sales@rdscientific.com
Country: Canada
ProdList: 1902
Advantage: 58

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View Lastest Price from H2N-PEG3-CH2COOtBu manufacturers

LAURENT

Product: NH2-PEG3-CH2COOtBu 189808-70-6
Price: US $69.00/g
Min. Order: 10g
Purity: 98%
Supply Ability: 500kg
Release date: 2025-11-17

R&D Scientific Inc.

Product: Amino-PEG3-CH2CO2-t-butyl ester 189808-70-6
Price: US $1500.00/g
Min. Order: 1g
Purity: 98
Supply Ability: 5000 Kg
Release date: 2025-05-07

189808-70-6, H2N-PEG3-CH2COOtBuRelated Search:

H2N-PEG2-CH2COOtBu 1-AMinooctaethylene Glycol TERT-BUTYL 12-AMINO-4 7 10-TRIOXA-DODECA 1,14-Diazido-3,6,9,12-tetraoxatetradecane 22-Amino-5,8,11,14,17,20-hexaoxa-2-azadocosanoic acid 1,1-dimethylethyl ester 2-[2-(2-Azidoethoxy)ethoxy]ethanamine alpha, oMega-DisucciniMidyl hexaethylene glycol 2-(2-Azidoethoxy)ethanol H2N-PEG11-CH2CH2COOH N3-PEG3-tBu Acid-PEG3-mono-methyl ester Amino-PEG10-alcohol Azide-PEG4-Tos alpha-aMine-oMega-propionic acid decaethylene glycol H2N-PEG12-tBu Azido-PEG7-azide Amino-PEG9-acid H2N-PEG24-CH2CH2COOtBu

H2N-PEG3-CH2COOtBu

Amino-PEG3-CH2CO2-t-butyl ester

tert-Butyl 2-(2-(2-(2-aminoethoxy)ethoxy)ethoxy)acetate

Amino-peg3-butyl ester

NH2-PEG3-C1-Boc

Acetic acid, 2-[2-[2-(2-aminoethoxy)ethoxy]ethoxy]-, 1,1-dimethylethyl ester

NH2-PEG3-CH2COOtBu

Amino-PEG3-CH2COOtBu

Amino-PEG3-CH2COOH t-Bu Ester

H2N-PEG3-CH2COOtBu/Acetic acid, 2-[2-[2-(2-aminoethoxy)ethoxy]ethoxy]-, 1,1-dimethylethyl ester

189808-70-6

PROTAC LINKER

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