METHYL 2-(3-BROMO-4-HYDROXYPHENYL)ACETATE
- Product Name
- METHYL 2-(3-BROMO-4-HYDROXYPHENYL)ACETATE
- CAS No.
- 34918-57-5
- Chemical Name
- METHYL 2-(3-BROMO-4-HYDROXYPHENYL)ACETATE
- Synonyms
- METHYL 2-(3-BROMO-4-HYDROXYPHENYL)ACETATE;Benzeneacetic acid, 3-bromo-4-hydroxy-, methyl ester
- CBNumber
- CB13561567
- Molecular Formula
- C9H9BrO3
- Formula Weight
- 245.07
- MOL File
- 34918-57-5.mol
METHYL 2-(3-BROMO-4-HYDROXYPHENYL)ACETATE Property
- Boiling point:
- 302.2±27.0 °C(Predicted)
- Density
- 1.562±0.06 g/cm3(Predicted)
- storage temp.
- 2-8°C
- pka
- 8.23±0.18(Predicted)
- Appearance
- Colorless to off-white Solid
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H315Causes skin irritation
H319Causes serious eye irritation
- Precautionary statements
-
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P332+P313IF SKIN irritation occurs: Get medical advice/attention.
P337+P313IF eye irritation persists: Get medical advice/attention.
N-Bromosuccinimide Price
- Product number
- A213006
- Product name
- Methyl2-(3-bromo-4-hydroxyphenyl)acetate
- Purity
- 95%
- Packaging
- 100mg
- Price
- $30
- Updated
- 2021/12/16
- Product number
- A213006
- Product name
- Methyl2-(3-bromo-4-hydroxyphenyl)acetate
- Purity
- 95%
- Packaging
- 250mg
- Price
- $40
- Updated
- 2021/12/16
- Product number
- A213006
- Product name
- Methyl2-(3-bromo-4-hydroxyphenyl)acetate
- Purity
- 95%
- Packaging
- 1g
- Price
- $98
- Updated
- 2021/12/16
- Product number
- A213006
- Product name
- Methyl2-(3-bromo-4-hydroxyphenyl)acetate
- Purity
- 95%
- Packaging
- 5g
- Price
- $327
- Updated
- 2021/12/16
- Product number
- CM252396
- Product name
- Methyl2-(3-bromo-4-hydroxyphenyl)acetate
- Purity
- 95%
- Packaging
- 1g
- Price
- $385
- Updated
- 2021/12/16
METHYL 2-(3-BROMO-4-HYDROXYPHENYL)ACETATE Chemical Properties,Usage,Production
Synthesis
67-56-1
38692-80-7
34918-57-5
Step 1: Synthesis of methyl 2-(3-bromo-4-hydroxyphenyl)acetate 3-Bromo-4-hydroxyphenylacetic acid (0.3 g, 1.3 mmol, 1.0 equiv) and concentrated H2SO4 (2.77 μL, 0.05 mmol, 0.04 equiv) were dissolved in methanol (10 mL). The reaction mixture was stirred for 1 h at room temperature. Upon completion of the reaction, the reaction was quenched with NaOH solution and subsequently extracted with ethyl acetate (EtOAc). The organic layers were combined, dried with anhydrous Na2SO4 and concentrated under reduced pressure. The crude product was purified by silica gel column chromatography (eluent: hexane/EtOAc = 5:1) to afford the target compound methyl 2-(3-bromo-4-hydroxyphenyl)acetate (0.2 g, 63% yield).LCMS m/z 245.0 [M + 1]+.
References
[1] Patent: WO2004/62661, 2004, A1. Location in patent: Page/Page column 28
[2] Patent: WO2010/138901, 2010, A1. Location in patent: Page/Page column 155
[3] Yakugaku Zasshi, 1933, vol. 53, p. 557,563; dtsch. Ref. S. 92
[4] Chem.Abstr., 1933, p. 4223
[5] Patent: WO2004/50637, 2004, A2. Location in patent: Page 74
METHYL 2-(3-BROMO-4-HYDROXYPHENYL)ACETATE Preparation Products And Raw materials
Raw materials
Preparation Products
METHYL 2-(3-BROMO-4-HYDROXYPHENYL)ACETATE Suppliers
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