(3R)-4-[dimethyl(trideuteriomethyl)azaniumyl]-3-tetradecanoyloxybutanoate:hydrochloride

(3R)-4-[dimethyl(trideuteriomethyl)azaniumyl]-3-tetradecanoyloxybutanoate:hydrochloride Property

storage temp. 

Store at -20°C

solubility 

DMF: 20 mg/ml,DMSO: 14 mg/ml,Ethanol: 20 mg/ml

form 

A solid

color 

White to off-white

Stability:

Hygroscopic

CAS Number Unlabeled

173686-73-2

Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P312Call a POISON CENTER or doctor/physician if you feel unwell.

P321Specific treatment (see … on this label).

P332+P313IF SKIN irritation occurs: Get medical advice/attention.

P337+P313IF eye irritation persists: Get medical advice/attention.

P403+P233Store in a well-ventilated place. Keep container tightly closed.

P405Store locked up.

P501Dispose of contents/container to..…

(3R)-4-[dimethyl(trideuteriomethyl)azaniumyl]-3-tetradecanoyloxybutanoate:hydrochloride Chemical Properties,Usage,Production

Description

Myristoyl-L-carnitine-d₃ is intended for use as an internal standard for the quantification of myristoyl-L-carnitine by GC- or LC-MS. Myristoyl-L-carnitine is a naturally occurring long-chain acylcarnitine. Plasma levels of myristoyl-L-carnitine are decreased in patients with chronic fatigue syndrome and increased in patients with end-stage renal disease.

Uses

Myristoyl-L-carnitine-d3 Hydrochloride is labelled Myristoyl-L-carnitine Hydrochloride (M884745), a long-chain fatty ester of carnitine which is accumulated and released into the circulation, in fatty-acid oxidation defects. Pattern of Lauroyl-L-carnitine can be diagnostic for a number of ?-oxidation defects.

References

[1] STEPHANIE E REUTER. Impact of haemodialysis on individual endogenous plasma acylcarnitine concentrations in end-stage renal disease.[J]. Annals of Clinical Biochemistry, 2005, 42 Pt 5: 387-393. DOI: 10.1258/0004563054889954
[2] S. E. REUTER  A. M E. Long-chain acylcarnitine deficiency in patients with chronic fatigue syndrome. Potential involvement of altered carnitine palmitoyltransferase-I activity[J]. Journal of Internal Medicine, 2010, 270 1: 76-84. DOI: 10.1111/j.1365-2796.2010.02341.x