Pyridazin-3-amine
- Product Name
- Pyridazin-3-amine
- CAS No.
- 5469-70-5
- Chemical Name
- Pyridazin-3-amine
- Synonyms
- 3-AMINOPYRIDAZINE;Pyridazin-3-ylamine;aminopyridazine;3-PYRIDAZINAMINE;PYRIDAZIN-3-AMINE;Pyridazin-2-amine;2-AMINOPYRIDAZINE;3-Amino pyradizine;Pyridazine-3-amine;3-amino-1,2-diazine
- CBNumber
- CB1406489
- Molecular Formula
- C4H5N3
- Formula Weight
- 95.1
- MOL File
- 5469-70-5.mol
Pyridazin-3-amine Property
- Melting point:
- 171 °C
- Boiling point:
- 326.2±15.0 °C(Predicted)
- Density
- 1.216±0.06 g/cm3(Predicted)
- storage temp.
- Keep in dark place,Sealed in dry,Room Temperature
- solubility
- soluble in Methanol
- pka
- 4.88±0.10(Predicted)
- form
- Solid
- color
- White to pale yellow
- InChI
- InChI=1S/C4H5N3/c5-4-2-1-3-6-7-4/h1-3H,(H2,5,7)
- InChIKey
- LETVJWLLIMJADE-UHFFFAOYSA-N
- SMILES
- C1(N)=NN=CC=C1
- CAS DataBase Reference
- 5469-70-5(CAS DataBase Reference)
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H302Harmful if swallowed
H319Causes serious eye irritation
- Precautionary statements
-
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P270Do not eat, drink or smoke when using this product.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P337+P313IF eye irritation persists: Get medical advice/attention.
N-Bromosuccinimide Price
- Product number
- 725048
- Product name
- 3-Aminopyridazine
- Purity
- 97%
- Packaging
- 500mg
- Price
- $166
- Updated
- 2023/06/20
- Product number
- A2048
- Product name
- 3-Aminopyridazine
- Purity
- >98.0%(GC)(T)
- Packaging
- 1g
- Price
- $25
- Updated
- 2025/07/31
- Product number
- A2048
- Product name
- 3-Aminopyridazine
- Purity
- >98.0%(GC)(T)
- Packaging
- 5g
- Price
- $71
- Updated
- 2025/07/31
- Product number
- A629058
- Product name
- 3-Aminopyridazine
- Packaging
- 100mg
- Price
- $75
- Updated
- 2021/12/16
- Product number
- 064947
- Product name
- Pyridazin-3-amine
- Purity
- 97%
- Packaging
- 1g
- Price
- $10
- Updated
- 2021/12/16
Pyridazin-3-amine Chemical Properties,Usage,Production
Chemical Properties
White to yellow to light brown powder or crystal
Uses
It is an important raw material and intermediate used in organic synthesis, pharmaceuticals, agrochemicals and dyestuffs.
Synthesis
5469-69-2
5469-70-5
General procedure for the synthesis of pyridazin-3-amine from 3-amino-6-chloropyridazine: (1) 6-chloropyridazin-3-amine (5.00 g, 38.6 mmol), tetrahydrofuran (240 mL), sodium hydroxide (8.00 g, 200 mmol), water (32 mL), and 10% palladium-carbon catalyst (500 mg) were mixed, and the reaction was stirred at room temperature in a hydrogen atmosphere for 2 days. After completion of the reaction, the insoluble material was removed by filtration and the filtrate was concentrated. The residue was dissolved in methanol (100 mL), filtered again to remove insoluble matter, and the filtrate was concentrated to quantitatively obtain the target product pyridazin-3-amine as a solid. 1H-NMR (DMSO-d6) δ: 2.51 (2H, broad peak), 6.46-6.49 (1H, multiple peaks), 6.93-6.97 (1H, multiple peaks), 8.06-8.08 (1H, multiple peaks).
References
[1] Patent: EP1813606, 2007, A1. Location in patent: Page/Page column 82
[2] European Journal of Medicinal Chemistry, 2015, vol. 105, p. 80 - 105
[3] Patent: US2011/9405, 2011, A1. Location in patent: Page/Page column 48
[4] Tetrahedron, 1993, vol. 49, # 3, p. 599 - 606
[5] Patent: US2008/261941, 2008, A1. Location in patent: Page/Page column 29
Pyridazin-3-amine Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from Pyridazin-3-amine manufacturers
- Product
- Pyridazin-3-amine 5469-70-5
- Price
- US $0.00-0.00/KG
- Min. Order
- 1KG
- Purity
- 98%
- Supply Ability
- 1ton
- Release date
- 2022-10-10
- Product
- aminopyridazine 5469-70-5
- Price
- US $200.00-1.00/KG
- Min. Order
- 1KG
- Purity
- 99%
- Supply Ability
- g-kg-tons, free sample is available
- Release date
- 2024-01-02
- Product
- Pyridazin-3-amine 3-AMinopyridazine 5469-70-5
- Price
- US $0.00-0.00/KG
- Min. Order
- 1g
- Purity
- 98%minHPLC
- Supply Ability
- 50kgs/month
- Release date
- 2021-11-13