3-Amino-6-cyanopyridine

Product Name: 3-Amino-6-cyanopyridine
CAS No.: 55338-73-3
Chemical Name: 3-Amino-6-cyanopyridine
Synonyms: 5-Aminopicolinonitrile;2-Cyano-5-Aminopyridine;5-AMINO-2-CYANOPYRIDINE;3-AMINO-6-CYANOPYRIDINE;5-Amino-2-pyridine nitrile;A**5-AMINO-2-CYANOPYRIDINE;5-Methyl pyridin-3-methanol;5-Aminopyridin-2-carbonitrile;3-AMino-6-pyridinecarbonitrile;2-carbonitrile-5-aminopyridine
CBNumber: CB1451232
Molecular Formula: C6H5N3
Formula Weight: 119.12
MOL File: 55338-73-3.mol

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3-Amino-6-cyanopyridine Property

Melting point:: 148-152 °C(lit.)
Boiling point:: 368.2±27.0 °C(Predicted)
Density: 1.23±0.1 g/cm3(Predicted)
storage temp.: Keep in dark place,Inert atmosphere,Room temperature
pka: 0.61±0.10(Predicted)
Appearance: Light yellow to brown Solid
InChI: InChI=1S/C6H5N3/c7-3-6-2-1-5(8)4-9-6/h1-2,4H,8H2
InChIKey: IFOXWHQFTSCNQB-UHFFFAOYSA-N
SMILES: C1(C#N)=NC=C(N)C=C1
CAS DataBase Reference: 55338-73-3(CAS DataBase Reference)

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Safety

Hazard Codes: Xn,Xi
Risk Statements: 20/21/22-36/37/38
Safety Statements: 26-36
RIDADR: 3439
WGK Germany: 3
HazardClass: 6.1
PackingGroup: III
HS Code: 2933399990

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: 538906
Product name: 5-Amino-2-pyridinecarbonitrile
Purity: 96%
Packaging: 25g
Price: $172.5
Updated: 2025/07/31

Sigma-Aldrich

Product number: 538906
Product name: 5-Amino-2-pyridinecarbonitrile
Purity: 96%
Packaging: 100g
Price: $284.5
Updated: 2025/07/31

TCI Chemical

Product number: A3358
Product name: 5-Aminopicolinonitrile
Purity: min. 98.0 %
Packaging: 1G
Price: $87
Updated: 2025/07/31

TCI Chemical

Product number: A3358
Product name: 5-Aminopicolinonitrile
Purity: min. 98.0 %
Packaging: 5G
Price: $262
Updated: 2025/07/31

TRC

Product number: A615410
Product name: 5-Aminopicolinonitrile
Packaging: 1g
Price: $55
Updated: 2021/12/16

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3-Amino-6-cyanopyridine Chemical Properties,Usage,Production

Chemical Properties

Brown powder

Uses

5-Amino-2-pyridinecarbonitrile (5-Amino-2-cyanopyridine) may be used to synthesize 5-amino-2-pyridine.

Synthesis

100367-55-3

55338-73-3

The general procedure for the synthesis of 3-amino-6-cyanopyridine from 2-cyano-5-nitropyridine was as follows: to a solution of 5-nitropyridine-2-carbonitrile (7.0 g, 46.9 mmol) in methanol (150 mL) was added 10% palladium carbon catalyst (2.0 g) and ammonium carbamate (7.0 g, 115 mmol). The reaction mixture was heated under reflux conditions for 16 hours. Upon completion of the reaction, the mixture was filtered to remove the catalyst and the filtrate was concentrated under reduced pressure. The concentrated residue was dissolved in water (150 mL) and subsequently extracted with ethyl acetate (150 mL × 3). The organic layers were combined, dried over anhydrous sodium sulfate, and then concentrated under reduced pressure to give 5.1 g of 5-aminopyridine-2-carbonitrile in 91.3% yield.

References

[1] Patent: WO2015/22301, 2015, A1. Location in patent: Page/Page column 28
[2] Journal of Medicinal Chemistry, 1994, vol. 37, # 1, p. 18 - 25
[3] Organic Process Research and Development, 2004, vol. 8, # 1, p. 62 - 71
[4] Patent: CN106810494, 2017, A. Location in patent: Paragraph 0030; 0031
[5] Patent: WO2017/184547, 2017, A1. Location in patent: Paragraph 00384

3-Amino-6-cyanopyridine Preparation Products And Raw materials

Raw materials

Preparation Products

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3-Amino-6-cyanopyridine Suppliers

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View Lastest Price from 3-Amino-6-cyanopyridine manufacturers

Shaanxi Dideu New Materials Co. Ltd

Product: 3-Amino-6-cyanopyridine 55338-73-3
Price: US $0.00-0.00/kg/Drum
Min. Order: 25kg/Drum
Purity: 98.0%
Supply Ability: 1000KG
Release date: 2025-04-29

Shaanxi Dideu Medichem Co. Ltd

Product: 3-Amino-6-cyanopyridine 55338-73-3
Price: US $1.10/g
Min. Order: 1g
Purity: 99.0% min
Supply Ability: 100 tons min
Release date: 2021-05-12

Henan Aochuang Chemical Co.,Ltd.

Product: 3-Amino-6-cyanopyridine 55338-73-3
Price: US $0.00-0.00/kg
Min. Order: 1kg
Purity: 98%
Supply Ability: 1Ton
Release date: 2022-10-14

55338-73-3, 3-Amino-6-cyanopyridineRelated Search:

2-Cyano-5-hydroxypyridine 4-Cyanopyridine 3-CYANO-5-METHYLPYRIDINE 4-Dimethylaminopyridine 3-Cyanopyridine ALTRENOGEST 3-Aminophenol 2-Chloro-3-cyanopyridine 2-Cyano-5-fluoropyridine 2-Cyanopyridine 2-Aminopyridine Glycine 3-Aminopyridine 6-Aminocaproic acid Tris(hydroxymethyl)aminomethane 2-Cyano-5-nitropyridine 5-Amino-3-methylpyridine-2-carbonitrile 3-AMINO-4-CYANOPYRIDINE

3-AMINO-6-CYANOPYRIDINE

5-AMINO-2-CYANOPYRIDINE

5-AMINO-PYRIDINE-2-CARBONITRILE

5-Aminopicolinonitrile

2-Cyano-5-Aminopyridine

5-Amino-2-pyridinecarbonitrile, 96%

5-Amino-2-pyridine nitrile

2-carbonitrile-5-aminopyridine

3-AMino-6-pyridinecarbonitrile

5-amino-2-cyanopyrdine（UNDER RD)

2-Pyridinecarbonitrile, 5-amino-

5-AMino-2-pyridinecarbonitrile 96%

3-Amino-6-cyanopyridine≥ 97% (HPLC)

3-Amino-6-cyanopyridine ISO 9001：2015 REACH

5-Methyl pyridin-3-methanol

2-Cyano-5-amino pyridine (or) 3-Amino-6-cyanopyridine

A**5-AMINO-2-CYANOPYRIDINE

5-Amino-2-pyridinecarbonitrile

5-Aminopyridin-2-carbonitrile

55338-73-3

55338-73-2

55338-73-7

Building Blocks

Pyridines

Heterocyclic Building Blocks

C6

Heterocycle-Pyridine series

Building Blocks

Chemical Synthesis

Heterocyclic Building Blocks

Pyridines

Pyridine

C6