Synthesis
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2-Fluoropyridine

Synthesis
Product Name
2-Fluoropyridine
CAS No.
372-48-5
Chemical Name
2-Fluoropyridine
Synonyms
2-CYANOPHENYLBORONIC ACID;2-Fluoropyride;2-Fluorpyridin;2-FLUOROPYRIDINE;2-fluoro-pyridin;o-fluoropyridine;2-Fluoroypyridine;2-Fluorpyridin CAS;2-fluoride pyridine;Pyridine, 2-fluoro-
CBNumber
CB1461659
Molecular Formula
C5H4FN
Formula Weight
97.09
MOL File
372-48-5.mol
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2-Fluoropyridine Property

Boiling point:
126 °C/753 mmHg (lit.)
Density 
1.128 g/mL at 25 °C (lit.)
refractive index 
n20/D 1.466(lit.)
Flash point:
83 °F
storage temp. 
Inert atmosphere,2-8°C
form 
Liquid
pka
-0.44(at 25℃)
color 
Clear colorless to light yellow
Specific Gravity
1.13
Water Solubility 
Soluble in water.
BRN 
1515
Dielectric constant
37.289999999999999
InChI
InChI=1S/C5H4FN/c6-5-3-1-2-4-7-5/h1-4H
InChIKey
MTAODLNXWYIKSO-UHFFFAOYSA-N
SMILES
C1(F)=NC=CC=C1
CAS DataBase Reference
372-48-5(CAS DataBase Reference)
NIST Chemistry Reference
2-Fluoropyridine(372-48-5)
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Safety

Hazard Codes 
Xi,F,Xn
Risk Statements 
10-36/37/38-20/21/22
Safety Statements 
26-36-36/37/39-16
RIDADR 
UN 1993 3/PG 3
WGK Germany 
3
RTECS 
UT3900000
Hazard Note 
Flammable/Irritant
HazardClass 
3
PackingGroup 
III
HS Code 
29333999
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H226Flammable liquid and vapour

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P210Keep away from heat/sparks/open flames/hot surfaces. — No smoking.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
F15250
Product name
2-Fluoropyridine
Purity
98%
Packaging
10g
Price
$38.2
Updated
2025/07/31
Sigma-Aldrich
Product number
F15250
Product name
2-Fluoropyridine
Purity
98%
Packaging
100g
Price
$235
Updated
2025/07/31
TCI Chemical
Product number
F0217
Product name
2-Fluoropyridine
Purity
>98.0%(GC)
Packaging
25g
Price
$62
Updated
2025/07/31
TCI Chemical
Product number
F0217
Product name
2-Fluoropyridine
Purity
>98.0%(GC)
Packaging
100g
Price
$183
Updated
2025/07/31
TRC
Product number
F596295
Product name
2-Fluoropyridine
Packaging
1g
Price
$55
Updated
2021/12/16
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2-Fluoropyridine Chemical Properties,Usage,Production

Synthesis

A rare example of fluorodenitration of a heterocyclic system was provided by 2- nitropyridine, which was converted to 2-fluoropyridine.

Chemical Properties

CLEAR COLOURLESS TO LIGHT YELLOW LIQUID

Uses

2-Fluoropyridine is a useful precursor of 2,3-disubstituted pyridines which is made by the possibility of metallation at C-3, together with the ready nucleophilic displacement of the activated fluorine. It can also react with thiophene to get 2-thiophen-2-yl-pyridine. It is used in the synthesis of aminopyridines.

2-Fluoropyridine Preparation Products And Raw materials

Raw materials

Preparation Products

2-Fluoro-3-pyridylboronic acid 2-(5-BROMO-2-THIENYL)PYRIDINE
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2-Fluoropyridine Suppliers

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View Lastest Price from 2-Fluoropyridine manufacturers

Shaanxi Dideu Medichem Co. Ltd
Product
2-Fluoropyridine 372-48-5
Price
US $1.10/g
Min. Order
1g
Purity
99.0% min
Supply Ability
100 tons min
Release date
2021-05-26
Hebei Chuanghai Biotechnology Co., Ltd
Product
2-Fluoropyridine 372-48-5
Price
US $30.00-10.00/KG
Min. Order
50KG
Purity
99%
Supply Ability
500000kg
Release date
2024-11-05
Henan Aochuang Chemical Co.,Ltd.
Product
2-Fluoropyridine 372-48-5
Price
US $0.00-0.00/KG
Min. Order
1KG
Purity
98%
Supply Ability
1ton
Release date
2022-10-12

372-48-5, 2-FluoropyridineRelated Search:

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  • 2-FLUOROPYRIDINE
  • 2-Fluorpyridin
  • 2-fluoro-pyridin
  • Pyridine, 2-fluoro-
  • 2-Fluoropyride
  • 2-Fluoroypyridine
  • 2-Fluoropyridine,99%
  • 2-CYANOPHENYLBORONIC ACID
  • 2-Fluoropyridine,98%
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  • 2-fluoride pyridine
  • o-fluoropyridine
  • 2-Fluoropyridine&gt
  • 2-Fluoropyridine, 98%, for synthesis
  • 3-Iodo-3-nitropyridine
  • 2-Fluoropyridine ISO 9001：2015 REACH
  • 2-Fluorpyridin CAS
  • 372-48-5
  • 372-48-2
  • 72-48-5
  • C5H4NF
  • Halopyridines
  • Fluoropyridines
  • Heterocyclic Building Blocks
  • Pyridines
  • Building Blocks
  • C5
  • Building Blocks
  • Chemical Synthesis
  • Fluorinated Building Blocks
  • Heterocyclic Building Blocks
  • Heterocyclic Fluorinated Building Blocks
  • Other Fluorinated Heterocycles
  • Fluorine series
  • alkyl Fluorine
  • Pyridine
  • pyridine derivative
  • Pyridines
  • Fluoropyridines
  • Halopyridines
  • C5
  • Heterocyclic Building Blocks
  • Fluorin-contained pyridine series
  • bc0001