ChemicalBook > CAS DataBase List > 1H-Benzimidazole, 2-(2-pyridinyl)-6-(trifluoromethoxy)-
1H-Benzimidazole, 2-(2-pyridinyl)-6-(trifluoromethoxy)-
- Product Name
- 1H-Benzimidazole, 2-(2-pyridinyl)-6-(trifluoromethoxy)-
- CAS No.
- 1256094-31-1
- Chemical Name
- 1H-Benzimidazole, 2-(2-pyridinyl)-6-(trifluoromethoxy)-
- Synonyms
- AI-10-47;AI-10-47, 10 mM in DMSO;1H-Benzimidazole, 2-(2-pyridinyl)-6-(trifluoromethoxy)-;2-(Pyridin-2-yl)-6-(trifluoromethoxy)-1H-benzo[d]imidazole;1H-Benzimidazole, 2-(2-pyridinyl)-6-(trifluoromethoxy)-AI-10-47;inhibit,leukemia,CBFβ,U937,AI1047,RUNX,Inhibitor,M0-91,ME-1,THP-1,TUR,AI 10 47,cell
- CBNumber
- CB18641176
- Molecular Formula
- C13H8F3N3O
- Formula Weight
- 279.22
- MOL File
- 1256094-31-1.mol
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1H-Benzimidazole, 2-(2-pyridinyl)-6-(trifluoromethoxy)- Property
- Boiling point:
- 411.7±55.0 °C(Predicted)
- Density
- 1.439±0.06 g/cm3(Predicted)
- form
- Solid
- pka
- 8.87±0.10(Predicted)
- color
- Off-white to gray
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N-Bromosuccinimide Price
Ambeed
- Product number
- A1448621
- Product name
- 2-(Pyridin-2-yl)-6-(trifluoromethoxy)-1H-benzo[d]imidazole
- Purity
- 98%
- Packaging
- 50mg
- Price
- $1130
- Updated
- 2021/12/16
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1H-Benzimidazole, 2-(2-pyridinyl)-6-(trifluoromethoxy)- Chemical Properties,Usage,Production
Description
AI-10-47 is a novel inhibitor of CBFβ-RUNX binding (IC50 of 3.2 μM).
Uses
AI-10-47 is a small molecule inhibitor of CBFβ-RUNX binding, with an IC50 of 3.2 μM[1].
References
[1] Anuradha Illendula, et al. Small Molecule Inhibitor of CBFβ-RUNX Binding for RUNX Transcription Factor Driven Cancers. EBioMedicine. 2016 Jun;8:117-131. DOI:10.1016/j.ebiom.2016.04.032
1H-Benzimidazole, 2-(2-pyridinyl)-6-(trifluoromethoxy)- Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from 1H-Benzimidazole, 2-(2-pyridinyl)-6-(trifluoromethoxy)- manufacturers
Shanghai Joiny Pharmaceutical Co.,LTD
- Product
- 1H-Benzimidazole, 2-(2-pyridinyl)-6-(trifluoromethoxy) 1256094-31-1
- Price
- US $0.00/kg
- Min. Order
- 1kg
- Purity
- 99%
- Supply Ability
- 1000kg
- Release date
- 2025-05-08