ETHYL 3-PIPERIDIN-4-YLPROPANOATE
- Product Name
- ETHYL 3-PIPERIDIN-4-YLPROPANOATE
- CAS No.
- 71879-55-5
- Chemical Name
- ETHYL 3-PIPERIDIN-4-YLPROPANOATE
- Synonyms
- Ethyl 4-piperidinepropanoate;ethyl 3-(4-piperidyl)propanoate;ETHYL 3-PIPERIDIN-4-YLPROPANOATE;4-(2-Ethoxycarbonylethyl)piperidine;4-piperidinepropanoic acid, ethyl ester;3-(4-piperidinyl)propanoic acid ethyl ester;3-Piperidin-4-yl-propionic acid ethyl ester
- CBNumber
- CB21517985
- Molecular Formula
- C10H19NO2
- Formula Weight
- 185.26
- MOL File
- 71879-55-5.mol
ETHYL 3-PIPERIDIN-4-YLPROPANOATE Property
- Boiling point:
- 252℃
- Density
- 0.959
- Flash point:
- 106℃
- pka
- 10.58±0.10(Predicted)
Safety
- HazardClass
- IRRITANT
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H302Harmful if swallowed
H315Causes skin irritation
H319Causes serious eye irritation
H332Harmful if inhaled
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- 040676
- Product name
- Ethyl 3-piperidin-4-ylpropanoate
- Packaging
- 500mg
- Price
- $315
- Updated
- 2021/12/16
- Product number
- CHM0392451
- Product name
- ETHYL-3-(PIPERIDIN-4-YL)PROPANOATE
- Purity
- 95.00%
- Packaging
- 5MG
- Price
- $499.25
- Updated
- 2021/12/16
- Product number
- 1159AC
- Product name
- Ethyl3-(piperidin-4-yl)propanoate
- Packaging
- 5g
- Price
- $1171
- Updated
- 2021/12/16
- Product number
- CD11067630
- Product name
- Ethyl3-(piperidin-4-yl)propanoate
- Purity
- 95+%
- Packaging
- 1g
- Price
- $385
- Updated
- 2021/12/16
- Product number
- 71879555
- Product name
- Ethyl3-(piperidin-4-yl)propanoate
- Packaging
- 1g
- Price
- $400
- Updated
- 2021/12/16
ETHYL 3-PIPERIDIN-4-YLPROPANOATE Chemical Properties,Usage,Production
Synthesis
123293-78-7
71879-55-5
General procedure for the synthesis of ethyl 3-piperidine-4-propanoate from ethyl (E)-3-(pyridin-4-yl)acrylate: a mixture of ethyl (E)-3-(pyridin-4-yl)acrylate (3 g, 16.95 mmol) and a palladium/carbon catalyst (0.5 g) in methanol (30 mL) was stirred at 40°C under a hydrogen atmosphere of 276 kPa (40 Psi) The reaction was carried out overnight. Upon completion of the reaction, the catalyst was removed by filtration and the filtrate was concentrated in vacuum to afford ethyl 3-piperidine-4-propionate (3 g, 95.8% yield). The product was analyzed by electrospray ionization mass spectrometry (ESI-MS), and the molecular ion peak (M+H)+ was measured to be 186, which was in accordance with the theoretically calculated molecular weight of 185.2 for C10H19NO2.
References
[1] Patent: WO2014/131855, 2014, A1. Location in patent: Page/Page column 68
[2] Journal of the Chemical Society, 1951, p. 1406,1408
[3] Journal of the Chemical Society, 1951, p. 1406,1408
[4] Chemical and Pharmaceutical Bulletin, 1993, vol. 41, # 3, p. 529 - 538
[5] Chemical and Pharmaceutical Bulletin, 1986, vol. 34, # 9, p. 3747 - 3761
ETHYL 3-PIPERIDIN-4-YLPROPANOATE Preparation Products And Raw materials
Raw materials
Preparation Products
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